MDNet: A Semantically and Visually Interpretable Medical Image Diagnosis Network

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal mapping between medical images and diagnostic reports that can read images, generate diagnostic reports, retrieve images by symptom descriptions, and visualize attention, to provide justifications of the network diagnosis process. MDNet includes an image model and a language model. The image model is proposed to enhance multi-scale feature ensembles and utilization efficiency. The language model, integrated with our improved attention mechanism, aims to read and explore discriminative image feature descriptions from reports to learn a direct mapping from sentence words to image pixels. The overall network is trained end-to-end by using our developed optimization strategy. Based on a pathology bladder cancer images and its diagnostic reports (BCIDR) dataset, we conduct sufficient experiments to demonstrate that MDNet outperforms comparative baselines. The proposed image model obtains state-of-the-art performance on two CIFAR datasets as well.Comment: CVPR2017 Ora

A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Deep Lesion Graphs in the Wild: Relationship Learning and Organization of Significant Radiology Image Findings in a Diverse Large-scale Lesion Database

Radiologists in their daily work routinely find and annotate significant abnormalities on a large number of radiology images. Such abnormalities, or lesions, have collected over years and stored in hospitals' picture archiving and communication systems. However, they are basically unsorted and lack semantic annotations like type and location. In this paper, we aim to organize and explore them by learning a deep feature representation for each lesion. A large-scale and comprehensive dataset, DeepLesion, is introduced for this task. DeepLesion contains bounding boxes and size measurements of over 32K lesions. To model their similarity relationship, we leverage multiple supervision information including types, self-supervised location coordinates and sizes. They require little manual annotation effort but describe useful attributes of the lesions. Then, a triplet network is utilized to learn lesion embeddings with a sequential sampling strategy to depict their hierarchical similarity structure. Experiments show promising qualitative and quantitative results on lesion retrieval, clustering, and classification. The learned embeddings can be further employed to build a lesion graph for various clinically useful applications. We propose algorithms for intra-patient lesion matching and missing annotation mining. Experimental results validate their effectiveness.Comment: Accepted by CVPR2018. DeepLesion url adde

Video Stream Retrieval of Unseen Queries using Semantic Memory

Retrieval of live, user-broadcast video streams is an under-addressed and increasingly relevant challenge. The on-line nature of the problem requires temporal evaluation and the unforeseeable scope of potential queries motivates an approach which can accommodate arbitrary search queries. To account for the breadth of possible queries, we adopt a no-example approach to query retrieval, which uses a query's semantic relatedness to pre-trained concept classifiers. To adapt to shifting video content, we propose memory pooling and memory welling methods that favor recent information over long past content. We identify two stream retrieval tasks, instantaneous retrieval at any particular time and continuous retrieval over a prolonged duration, and propose means for evaluating them. Three large scale video datasets are adapted to the challenge of stream retrieval. We report results for our search methods on the new stream retrieval tasks, as well as demonstrate their efficacy in a traditional, non-streaming video task.Comment: Presented at BMVC 2016, British Machine Vision Conference, 201

A Meta-Analysis of Evolution of Deep Learning Research in Medical Image Analysis

With a text mining and bibliometrics approach, we review the literature on the evolution of deep learning in medical image literature from 2012 – 2020 in order to understand the current state of the research and to identify the major research themes in image analysis to answer our research questions: RQ1: What are the learning modes that are evident in the literature? RQ2: What are the emerging learning modes in the literature? RQ3: What are the major themes in medical imaging literature? The analysis of 8704 resulting from a data collection process from peer-reviewed databases, our analysis discovered the six major themes of image segmentation studies, studies with image classification, evaluation procedures such as sensitivity and specificity, optical coherence tomography studies, MRI imaging studies, and Chest imaging studies. Additionally, we assessed the number of articles published each year, the frequent keywords, the author networks, the trending topics, and connections to other topics. We discovered that segmenting and classifying the images are the most common tasks. Transfer learning is the most researched area and cancer is the highly targeted disease and Covid-19 is the most recent research tren

Hi, how can I help you?: Automating enterprise IT support help desks

Question answering is one of the primary challenges of natural language understanding. In realizing such a system, providing complex long answers to questions is a challenging task as opposed to factoid answering as the former needs context disambiguation. The different methods explored in the literature can be broadly classified into three categories namely: 1) classification based, 2) knowledge graph based and 3) retrieval based. Individually, none of them address the need of an enterprise wide assistance system for an IT support and maintenance domain. In this domain the variance of answers is large ranging from factoid to structured operating procedures; the knowledge is present across heterogeneous data sources like application specific documentation, ticket management systems and any single technique for a general purpose assistance is unable to scale for such a landscape. To address this, we have built a cognitive platform with capabilities adopted for this domain. Further, we have built a general purpose question answering system leveraging the platform that can be instantiated for multiple products, technologies in the support domain. The system uses a novel hybrid answering model that orchestrates across a deep learning classifier, a knowledge graph based context disambiguation module and a sophisticated bag-of-words search system. This orchestration performs context switching for a provided question and also does a smooth hand-off of the question to a human expert if none of the automated techniques can provide a confident answer. This system has been deployed across 675 internal enterprise IT support and maintenance projects.Comment: To appear in IAAI 201