5,730 research outputs found

    Coupling Artificial Intelligence Capability and Strategic Agility for Enhanced Product and Service Creativity

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    Creativity is key for organizations’ ability to remain relevant in today's disruptive world. In this paper, we identify new ways in which organizations can use artificial intelligence (AI) more effectively for creativity. Drawing on the resource‐based view as a background mechanism, we developed and empirically tested a new integrative model. We collected the research data via a large survey of managers distributed to 600 organizations in China. Our findings show that coupling AI capability with strategic agility can directly support creativity. It also mediates the effects of ambidexterity, customer orientation and competitor orientation on organizations’ creativity and performance when developing new products and services. In addition, our findings show that coupling AI capability and strategic agility can significantly improve firms’ new product creativity and new service development performance when there is a high level of government institutional support. Our findings provide theoretical and practical implications for academics and practitioners interested in managing AI for organizational creativity

    Nexus between agriculture and photovoltaics (agrivoltaics, agriphotovoltaics) for sustainable development goal: A review

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    This is the final version. Available on open access from Elsevier via the DOI in this recordThe coexistence of agricultural land and solar photovoltaics (PV) can be named Agriphotovoltaics (APV). APV concept was developed two decades ago however its actual implementation is happening nowadays. APV directly solves SDGs 7, and 11 by generating benevolent renewable energy without damaging the land and keep producing food for people. In this work, a comprehensive review of the APV system is documented. Currently available software tools, field experiment results, and PV for APV are described in this work which identified that for forecasting APV, a more robust tool is required. Vertically placed Bifacial PV, transparent, and semitransparent tilted PVs can be suitable for shade-intolerant crops whereas opaque PVs are appropriate for shade-tolerant crops. The knowledge gap between various stakeholders such as solar PV researchers, agricultural researchers, and land users needs to be more rigorous. Economic and policymakers should share dialogue to improve the growth of APV which not only solves SDG 7, and 11 but also meets the target for SDG 5, 8, 9,12, and 15

    The fallacies of non-agility: Approaching organizational agility through a dialectical practice perspective

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    Complexity, paradox, tension, and contradiction are increasingly seen as permeating all aspects of organizational life. Yet despite ongoing advancement, both our understanding of the nature of complexity as well as how to use this increased appreciation of it in practice are still developing. In this spirit, this paper considers organizational agility and how to achieve it. Here, current discussions of organizational agility have failed to sufficiently address the fundamental tensions inherent in learning stemming from conflicting goals and incentives, evident in an ongoing discussion of theory-informed approaches for bringing about organizational agility. In this paper, we claim that incorporating a dialectical perspective of learning would provide a means of understanding the successes and failures of practices aimed at bringing about agility. We consider the maligned dialectic, four fallacious ways of thinking that hinder agility, and the extent to which these can be overcome. As evidence, we present a case of Agile implementation in which one of the authors acted as a consultant and involving a large-scale social change. Considering this from a dialectical perspective, we discuss ways that dysfunction in achieving agility might be reduced through disruptive interventions like Agile

    The fallacies of non-agility: Approaching organizational agility through a dialectical practice perspective

    Full text link
    Complexity, paradox, tension, and contradiction are increasingly seen as permeating all aspects of organizational life. Yet despite ongoing advancement, both our understanding of the nature of complexity as well as how to use this increased appreciation of it in practice are still developing. In this spirit, this paper considers organizational agility and how to achieve it. Here, current discussions of organizational agility have failed to sufficiently address the fundamental tensions inherent in learning stemming from conflicting goals and incentives, evident in an ongoing discussion of theory-informed approaches for bringing about organizational agility. In this paper, we claim that incorporating a dialectical perspective of learning would provide a means of understanding the successes and failures of practices aimed at bringing about agility. We consider the maligned dialectic, four fallacious ways of thinking that hinder agility, and the extent to which these can be overcome. As evidence, we present a case of Agile implementation in which one of the authors acted as a consultant and involving a large-scale social change. Considering this from a dialectical perspective, we discuss ways that dysfunction in achieving agility might be reduced through disruptive interventions like Agile

    A field experiment on gamification of physical activity – effects on motivation and steps

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    Gamification is finding growing application in the field of physical activity, promising engaging and motivating experiences that foster behavioural change. Yet, rigorous empirical work substantiating favourable claims is limited. Our study sought to find evidence for the effects resulting from gamification of physical activity on the users’ motivation, perceived usefulness, and the behavioural change in terms of step counts. We employed a four-week randomised controlled field experiment to investigate how the choice of different gamification designs affects outcomes. Participants were provided with a wearable physical activity tracker and randomly assigned to either a: 1) competitive gamified group; 2) cooperative gamified group; 3) hybrid gamified group; or 4) control group. Data gathered includes a panel dataset of step counts and self-reported data on the users’ intrinsic motivation and perceived usefulness. We found that at the end of the intervention, gamification made no difference to self-assessed intrinsic motivation or perceived usefulness compared to a non-gamified self-tracking experience. Yet, despite the lack of psychological effects, the use of gamification did result in stronger behavioural outcomes relative to the control group - in the form of increased step counts. Indeed, all groups treated with gamification recorded an increase in step counts during the intervention period. Furthermore, among the gamified treatments, it was the hybrid design that generated the largest difference in step counts (relative to the control group). The finding that gamification can stimulate a stronger behavioural outcome without stimulating a stronger psychological one merits further investigation as to the mechanisms at play.peer-reviewe

    Leveraging social media, big data, and smart technologies for intercultural communication and effective leadership: Empirical study at the Ministry of Digital Economy and Entrepreneurship

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    The objective of this study was to evaluate the impact of social media, big data, and smart technology on intercultural communication and effective leadership inside the Ministry of digital & entrepreneurship. The main objective was to investigate the influence of these technical elements on organizational behavior and the efficacy of leadership within the particular setting of a government ministry dedicated to digital economy and entrepreneurship. In order to accomplish this goal, a thorough empirical inquiry was done, which included gathering data from important individuals involved in the Ministry. The study intentionally selected a sample size of 379 individuals, who represented various responsibilities within the Ministry. The process of data gathering entailed the distribution of surveys and the conduction of interviews to acquire valuable insights and viewpoints from the participants. The utilization of this approach yielded a resilient dataset that is well-suited for thorough investigation. The study explored the complex connection between the use of social media platforms, the implementation of big data analytics, and the incorporation of smart technologies in influencing the dynamics of intercultural communication and leadership inside the Ministry. The results emphasized the substantial influence of social media in promoting intercultural communication and cooperation among personnel within the Ministry. Moreover, the implementation of big data analytics has become a crucial element in improving decision-making processes, impacting several facets of leadership efficacy, strategic planning, and employee involvement. Smart technologies were recognized as crucial elements in establishing efficient communication channels and facilitating effective leadership practices. The study's findings emphasized the beneficial impacts of utilizing social media, big data, and smart technology in the Ministry of digital & entrepreneurship. The research highlighted the significance of government organizations incorporating these technologies in a proactive manner to foster a work environment characterized by improved multicultural communication, well-informed decision-making and efficient leadership. This study makes a substantial contribution to the comprehension of how technological improvements might influence organizational behavior and leadership practices in a government setting. It provides essential insights for policymakers, leaders, and researchers. The findings have broader significance beyond the Ministry, serving as a basis for additional investigation into the use of technology in intercultural communication and leadership effectiveness inside government institutions

    Organizing sustainable development

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    The role and meaning of sustainable development have been recognized in the scientific literature for decades. However, there has recently been a dynamic increase in interest in the subject, which results in numerous, in-depth scientific research and publications with an interdisciplinary dimension. This edited volume is a compendium of theoretical knowledge on sustainable development. The context analysed in the publication includes a multi-level and multi-aspect analysis starting from the historical and legal conditions, through elements of the macro level and the micro level, inside the organization. Organizing Sustainable Development offers a systematic and comprehensive theoretical analysis of sustainable development supplemented with practical examples, which will allow obtaining comprehensive knowledge about the meaning and its multi-context application in practice. It shows the latest state of knowledge on the topic and will be of interest to students at an advanced level, academics and reflective practitioners in the fields of sustainable development, management studies, organizational studies and corporate social responsibility

    The Human Phenotype Ontology in 2024: phenotypes around the world.

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    The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in addition to English. Since our last report, a total of 2239 new HPO terms and 49235 new HPO annotations were developed, many in collaboration with external groups in the fields of psychiatry, arthrogryposis, immunology and cardiology. The Medical Action Ontology (MAxO) is a new effort to model treatments and other measures taken for clinical management. Finally, the HPO consortium is contributing to efforts to integrate the HPO and the GA4GH Phenopacket Schema into electronic health records (EHRs) with the goal of more standardized and computable integration of rare disease data in EHRs

    Pathophysiological role and therapeutic potential of extracellular vesicles in cancer

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    Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are endogenously generated through various biogenesis pathways within most cellular entities. Subsequently, they are released into the extracellular milieu to facilitate intercellular communication. They are composed of diverse bioactive molecules with important roles in physiological and pathological states. Over the past few decades, the therapeutic potential of EVs has garnered significant interest in the drug delivery field. However, deepened understanding of EV biology and further technological advances are needed to bridge the gap between research and clinical translation. In this thesis, we address these challenges and investigate EVs as novel biomedical agents. EVs are crucial components of physiological processes and disease development. Sensitive visualisation techniques are needed to better understand their function as therapeutic agents. In paper I, a bioluminescent labelling system was developed to track EVs in vitro and in vivo. The system uses genetic modifications to enable the encapsulation of sensitive luciferase-variants in EVs. The system was used in vivo to enable highly sensitive detection of EV distribution pattern. Exogenously administered EVs were found to rapidly distribute within different organs, with a preference for the spleen, lung, and liver. In addition to endogenously engineered EVs for in vivo tracking, exogenously engineered EVs can be utilised as promising drug delivery platforms. However, cargo loading is often insufficient, requiring improved EV loading approaches. In paper II, we developed an optimised cargo loading method using electroporation. An optimised protocol was designed to load EVs with doxorubicin, which increased cargo loading, EV recovery, and drug potency by 190-fold over free doxorubicin. Owing to their potential to cross biological barriers, transport bioactive cargo, and targetability, EVs can be exploited as delivery vehicles for targeting of therapeutics. EVs were used as delivery vectors in paper III by coating their surfaces with an Fc domain-specific antibodybinding moiety. These Fc-EVs were then decorated with various IgG antibodies and targeted to cells of interest. In vitro and in vivo antibody targeting studies showed the broad potential of this technology for cancer therapy. The platform efficiently targeted EVs to cancer cells, including HER2 and PD-L1 positive cells. As proof of concept, Fc-EVs with PD-L1 antibody accumulate in tumour tissue and, when loaded with doxorubicin, reduce tumour burden, and increase survival in melanoma-bearing mice. Despite significant EV engineering advances, we have a limited understanding of the biology of tumour-derived extracellular vesicles (tEVs). In paper IV, we investigated the role of in vitrogenerated melanoma-derived EVs as indirect communicators in tumour-induced haematopoiesis dysregulation. The tEVs, which contain high levels of angiogenic factors like VEGF, osteopontin, and tissue factor, were found to cause splenomegaly, extramedullary haematopoiesis, expansion of splenic immature erythroid progenitors, reduced bone marrow cellularity, medullary expansion of granulocytic myeloid suppressor cells, and anaemia in syngeneic mice. These findings suggest that tEVs dysregulate haematopoiesis during the immune escape phase of cancer immunoediting, making them potential targets for overcoming immune evasion and restoring normal haematopoiesis. To summarise, the tools generated in this thesis, including the ability to detect EVs in vivo, effective cargo loading, display antibody binding moieties on EV surfaces for targeting, and understanding the pathophysiological role of tEVs, contribute to the advancement of EVs for biomedical purposes, and clinical translation down the line

    Southern Adventist University Undergraduate Catalog 2023-2024

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    Southern Adventist University\u27s undergraduate catalog for the academic year 2023-2024.https://knowledge.e.southern.edu/undergrad_catalog/1123/thumbnail.jp
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