Automated detection of brain abnormalities in neonatal hypoxia ischemic injury from MR images.

We compared the efficacy of three automated brain injury detection methods, namely symmetry-integrated region growing (SIRG), hierarchical region splitting (HRS) and modified watershed segmentation (MWS) in human and animal magnetic resonance imaging (MRI) datasets for the detection of hypoxic ischemic injuries (HIIs). Diffusion weighted imaging (DWI, 1.5T) data from neonatal arterial ischemic stroke (AIS) patients, as well as T2-weighted imaging (T2WI, 11.7T, 4.7T) at seven different time-points (1, 4, 7, 10, 17, 24 and 31 days post HII) in rat-pup model of hypoxic ischemic injury were used to assess the temporal efficacy of our computational approaches. Sensitivity, specificity, and similarity were used as performance metrics based on manual ('gold standard') injury detection to quantify comparisons. When compared to the manual gold standard, automated injury location results from SIRG performed the best in 62% of the data, while 29% for HRS and 9% for MWS. Injury severity detection revealed that SIRG performed the best in 67% cases while 33% for HRS. Prior information is required by HRS and MWS, but not by SIRG. However, SIRG is sensitive to parameter-tuning, while HRS and MWS are not. Among these methods, SIRG performs the best in detecting lesion volumes; HRS is the most robust, while MWS lags behind in both respects

Advanced content-based semantic scene analysis and information retrieval: the SCHEMA project

The aim of the SCHEMA Network of Excellence is to bring together a critical mass of universities, research centers, industrial partners and end users, in order to design a reference system for content-based semantic scene analysis, interpretation and understanding. Relevant research areas include: content-based multimedia analysis and automatic annotation of semantic multimedia content, combined textual and multimedia information retrieval, semantic -web, MPEG-7 and MPEG-21 standards, user interfaces and human factors. In this paper, recent advances in content-based analysis, indexing and retrieval of digital media within the SCHEMA Network are presented. These advances will be integrated in the SCHEMA module-based, expandable reference system

Region-based segmentation of images using syntactic visual features

This paper presents a robust and efficient method for segmentation of images into large regions that reflect the real world objects present in the scene. We propose an extension to the well known Recursive Shortest Spanning Tree (RSST) algorithm based on a new color model and so-called syntactic features [1]. We introduce practical solutions, integrated within the RSST framework, to structure analysis based on the shape and spatial configuration of image regions. We demonstrate that syntactic features provide a reliable basis for region merging criteria which prevent formation of regions spanning more than one semantic object, thereby significantly improving the perceptual quality of the output segmentation. Experiments indicate that the proposed features are generic in nature and allow satisfactory segmentation of real world images from various sources without adjustment to algorithm parameters

Multi-feature Bottom-up Processing and Top-down Selection for an Object-based Visual Attention Model

Artificial vision systems can not process all the information that they receive from the world in real time because it is highly expensive and inefficient in terms of computational cost. However, inspired by biological perception systems, it is possible to develop an artificial attention model able to select only the relevant part of the scene, as human vision does. This paper presents an attention model which draws attention over perceptual units of visual information, called proto-objects, and which uses a linear combination of multiple low-level features (such as colour, symmetry or shape) in order to calculate the saliency of each of them. But not only bottom-up processing is addressed, the proposed model also deals with the top-down component of attention. It is shown how a high-level task can modulate the global saliency computation, modifying the weights involved in the basic features linear combination.Ministerio de Economía y Competitividad (MINECO), proyectos: TIN2008-06196 y TIN2012-38079-C03-03. Campus de Excelencia Internacional Andalucía Tech

Automated tracking of colloidal clusters with sub-pixel accuracy and precision

Quantitative tracking of features from video images is a basic technique employed in many areas of science. Here, we present a method for the tracking of features that partially overlap, in order to be able to track so-called colloidal molecules. Our approach implements two improvements into existing particle tracking algorithms. Firstly, we use the history of previously identified feature locations to successfully find their positions in consecutive frames. Secondly, we present a framework for non-linear least-squares fitting to summed radial model functions and analyze the accuracy (bias) and precision (random error) of the method on artificial data. We find that our tracking algorithm correctly identifies overlapping features with an accuracy below 0.2% of the feature radius and a precision of 0.1 to 0.01 pixels for a typical image of a colloidal cluster. Finally, we use our method to extract the three-dimensional diffusion tensor from the Brownian motion of colloidal dimers.Comment: 20 pages, 8 figures. Non-revised preprint version, please refer to http://dx.doi.org/10.1088/1361-648X/29/4/04400

Accurate and reliable segmentation of the optic disc in digital fundus images

We describe a complete pipeline for the detection and accurate automatic segmentation of the optic disc in digital fundus images. This procedure provides separation of vascular information and accurate inpainting of vessel-removed images, symmetry-based optic disc localization, and fitting of incrementally complex contour models at increasing resolutions using information related to inpainted images and vessel masks. Validation experiments, performed on a large dataset of images of healthy and pathological eyes, annotated by experts and partially graded with a quality label, demonstrate the good performances of the proposed approach. The method is able to detect the optic disc and trace its contours better than the other systems presented in the literature and tested on the same data. The average error in the obtained contour masks is reasonably close to the interoperator errors and suitable for practical applications. The optic disc segmentation pipeline is currently integrated in a complete software suite for the semiautomatic quantification of retinal vessel properties from fundus camera images (VAMPIRE)

A stochastic-variational model for soft Mumford-Shah segmentation

In contemporary image and vision analysis, stochastic approaches demonstrate great flexibility in representing and modeling complex phenomena, while variational-PDE methods gain enormous computational advantages over Monte-Carlo or other stochastic algorithms. In combination, the two can lead to much more powerful novel models and efficient algorithms. In the current work, we propose a stochastic-variational model for soft (or fuzzy) Mumford-Shah segmentation of mixture image patterns. Unlike the classical hard Mumford-Shah segmentation, the new model allows each pixel to belong to each image pattern with some probability. We show that soft segmentation leads to hard segmentation, and hence is more general. The modeling procedure, mathematical analysis, and computational implementation of the new model are explored in detail, and numerical examples of synthetic and natural images are presented.Comment: 22 page