Surrogate Spike Train Generation Through Dithering in Operational Time

Detecting the excess of spike synchrony and testing its significance can not be done analytically for many types of spike trains and relies on adequate surrogate methods. The main challenge for these methods is to conserve certain features of the spike trains, the two most important being the firing rate and the inter-spike interval statistics. In this study we make use of operational time to introduce generalizations to spike dithering and propose two novel surrogate methods which conserve both features with high accuracy. Compared to earlier approaches, the methods show an improved robustness in detecting excess synchrony between spike trains

State-Space Analysis of Time-Varying Higher-Order Spike Correlation for Multiple Neural Spike Train Data

Precise spike coordination between the spiking activities of multiple neurons is suggested as an indication of coordinated network activity in active cell assemblies. Spike correlation analysis aims to identify such cooperative network activity by detecting excess spike synchrony in simultaneously recorded multiple neural spike sequences. Cooperative activity is expected to organize dynamically during behavior and cognition; therefore currently available analysis techniques must be extended to enable the estimation of multiple time-varying spike interactions between neurons simultaneously. In particular, new methods must take advantage of the simultaneous observations of multiple neurons by addressing their higher-order dependencies, which cannot be revealed by pairwise analyses alone. In this paper, we develop a method for estimating time-varying spike interactions by means of a state-space analysis. Discretized parallel spike sequences are modeled as multi-variate binary processes using a log-linear model that provides a well-defined measure of higher-order spike correlation in an information geometry framework. We construct a recursive Bayesian filter/smoother for the extraction of spike interaction parameters. This method can simultaneously estimate the dynamic pairwise spike interactions of multiple single neurons, thereby extending the Ising/spin-glass model analysis of multiple neural spike train data to a nonstationary analysis. Furthermore, the method can estimate dynamic higher-order spike interactions. To validate the inclusion of the higher-order terms in the model, we construct an approximation method to assess the goodness-of-fit to spike data. In addition, we formulate a test method for the presence of higher-order spike correlation even in nonstationary spike data, e.g., data from awake behaving animals. The utility of the proposed methods is tested using simulated spike data with known underlying correlation dynamics. Finally, we apply the methods to neural spike data simultaneously recorded from the motor cortex of an awake monkey and demonstrate that the higher-order spike correlation organizes dynamically in relation to a behavioral demand

29th Annual Computational Neuroscience Meeting: CNS*2020

Meeting abstracts This publication was funded by OCNS. The Supplement Editors declare that they have no competing interests. Virtual | 18-22 July 202

Techniques for Decentralized and Dynamic Resource Allocation

abstract: This thesis investigates three different resource allocation problems, aiming to achieve two common goals: i) adaptivity to a fast-changing environment, ii) distribution of the computation tasks to achieve a favorable solution. The motivation for this work relies on the modern-era proliferation of sensors and devices, in the Data Acquisition Systems (DAS) layer of the Internet of Things (IoT) architecture. To avoid congestion and enable low-latency services, limits have to be imposed on the amount of decisions that can be centralized (i.e. solved in the ``cloud") and/or amount of control information that devices can exchange. This has been the motivation to develop i) a lightweight PHY Layer protocol for time synchronization and scheduling in Wireless Sensor Networks (WSNs), ii) an adaptive receiver that enables Sub-Nyquist sampling, for efficient spectrum sensing at high frequencies, and iii) an SDN-scheme for resource-sharing across different technologies and operators, to harmoniously and holistically respond to fluctuations in demands at the eNodeB' s layer. The proposed solution for time synchronization and scheduling is a new protocol, called PulseSS, which is completely event-driven and is inspired by biological networks. The results on convergence and accuracy for locally connected networks, presented in this thesis, constitute the theoretical foundation for the protocol in terms of performance guarantee. The derived limits provided guidelines for ad-hoc solutions in the actual implementation of the protocol. The proposed receiver for Compressive Spectrum Sensing (CSS) aims at tackling the noise folding phenomenon, e.g., the accumulation of noise from different sub-bands that are folded, prior to sampling and baseband processing, when an analog front-end aliasing mixer is utilized. The sensing phase design has been conducted via a utility maximization approach, thus the scheme derived has been called Cognitive Utility Maximization Multiple Access (CUMMA). The framework described in the last part of the thesis is inspired by stochastic network optimization tools and dynamics. While convergence of the proposed approach remains an open problem, the numerical results here presented suggest the capability of the algorithm to handle traffic fluctuations across operators, while respecting different time and economic constraints. The scheme has been named Decomposition of Infrastructure-based Dynamic Resource Allocation (DIDRA).Dissertation/ThesisDoctoral Dissertation Electrical Engineering 201