Autism Spectrum Disorders Gait Identification Using Ground Reaction Forces

 Autism spectrum disorders (ASD) are a permanent neurodevelopmental disorder that can be identified during the first few years of life and are currently associated with the abnormal walking pattern. Earlier identification of this pervasive disorder could provide assistance in diagnosis and establish rapid quantitative clinical judgment. This paper presents an automated approach which can be applied to identify ASD gait patterns using three-dimensional (3D) ground reaction forces (GRF). The study involved classification of gait patterns of children with ASD and typical healthy children. The GRF data were obtained using two force plates during self-determined barefoot walking. Time-series parameterization techniques were applied to the GRF waveforms to extract the important gait features. The most dominant and correct features for characterizing ASD gait were selected using statistical between-group tests and stepwise discriminant analysis (SWDA). The selected features were grouped into two groups which served as two input datasets to the k-nearest neighbor (KNN) classifier. This study demonstrates that the 3D GRF gait features selected using SWDA are reliable to be used in the identification of ASD gait using KNN classifier with 83.33% performance accuracy.

Automatic recognition of gait patterns in human motor disorders using machine learning: A review

Background: automatic recognition of human movement is an effective strategy to assess abnormal gait patterns. Machine learning approaches are mainly applied due to their ability to work with multidimensional nonlinear features. Purpose: to compare several machine learning algorithms employed for gait pattern recognition in motor disorders using discriminant features extracted from gait dynamics. Additionally, this work highlights procedures that improve gait recognition performance. Methods: we conducted an electronic literature search on Web of Science, IEEE, and Scopus, using “human recognition”, “gait patterns’’, and “feature selection methods” as relevant keywords. Results: analysis of the literature showed that kernel principal component analysis and genetic algorithms are efficient at reducing dimensional features due to their ability to process nonlinear data and converge to global optimum. Comparative analysis of machine learning performance showed that support vector machines (SVMs) exhibited higher accuracy and proper generalization for new instances. Conclusions: automatic recognition by combining dimensional data reduction, cross-validation and normalization techniques with SVMs may offer an objective and rapid tool for investigating the subject's clinical status. Future directions comprise the real-time application of these tools to drive powered assistive devices in free-living conditions.This work was supported by the FCT - Fundação para a Ciência e Tecnologia - with the reference scholarship SFRH/BD/108309/2015, and the reference project UID/EEA/04436/2013, by FEDER funds through the COMPETE 2020 - Programa Operacional Competitividade e Internacionalização (POCI) - with the reference project POCI-01-0145-FEDER-006941. Also, this work was partially supported by grant RYC-2014-16613 by Spanish Ministry of Economy and Competitiveness

Gait-Based Diplegia Classification Using LSMT Networks

Diplegia is a specific subcategory of the wide spectrum of motion disorders gathered under the name of cerebral palsy. Recent works proposed to use gait analysis for diplegia classification paving the way for automated analysis. A clinically established gait-based classification system divides diplegic patients into 4 main forms, each one associated with a peculiar walking pattern. In this work, we apply two different deep learning techniques, namely, multilayer perceptron and recurrent neural networks, to automatically classify children into the 4 clinical forms. For the analysis, we used a dataset comprising gait data of 174 patients collected by means of an optoelectronic system. The measurements describing walking patterns have been processed to extract 27 angular parameters and then used to train both kinds of neural networks. Classification results are comparable with those provided by experts in 3 out of 4 forms

Autism Spectrum Disorder and Normal Gait Classification Using Machine Learning Approach

Previous research has reported that children with autism spectrum disorder (ASD) exhibit unusual movement and atypical gait patterns. Automated classification of abnormal gait from normal gait can serve as a potential tool for early and objective diagnosis as well as post-treatment monitoring. The aim of this study is to employ machine learning approaches to differentiate between children with ASD and healthy controls by utilizing gait features extracted from three-dimensional (3D) gait analysis data. The gait data of 30 children with ASD and 30 healthy controls were obtained using 3D gait analysis during walking at a normal pace. Time-series parameterization techniques were applied to the kinematic and kinetic waveforms to extract useful gait features. Further, the dominant gait features were selected using statistical feature selection techniques. To highlight the efficacy of different machine learning classifiers towards devising an accurate gait classification, four machine learning classifiers were trained to classify ASD and control gait based on the selected dominant gait features. The classifiers are Artificial Neural Networks (ANN), Support Vector Machines (SVMs), K-Nearest Neighbor (KNN), and Linear Discriminant Analysis (LDA). The 10-fold cross-validation test results indicate that the ANN-SCG classifier with six dominant gait features was able to produce the optimum classification performance with 98.3% accuracy, 96.7% sensitivity, and 100% specificity. The findings indicate that the ANN classifier has the potential to serve as a valuable tool for assisting in the diagnosis of ASD gait and evaluating treatment programs

A Two-stream Convolutional Network for Musculoskeletal and Neurological Disorders Prediction

Musculoskeletal and neurological disorders are the most common causes of walking problems among older people, and they often lead to diminished quality of life. Analyzing walking motion data manually requires trained professionals and the evaluations may not always be objective. To facilitate early diagnosis, recent deep learning-based methods have shown promising results for automated analysis, which can discover patterns that have not been found in traditional machine learning methods. We observe that existing work mostly applies deep learning on individual joint features such as the time series of joint positions. Due to the challenge of discovering inter-joint features such as the distance between feet (i.e. the stride width) from generally smaller-scale medical datasets, these methods usually perform sub-optimally. As a result, we propose a solution that explicitly takes both individual joint features and inter-joint features as input, relieving the system from the need of discovering more complicated features from small data. Due to the distinctive nature of the two types of features, we introduce a two-stream framework, with one stream learning from the time series of joint position and the other from the time series of relative joint displacement. We further develop a mid-layer fusion module to combine the discovered patterns in these two streams for diagnosis, which results in a complementary representation of the data for better prediction performance. We validate our system with a benchmark dataset of 3D skeleton motion that involves 45 patients with musculoskeletal and neurological disorders, and achieve a prediction accuracy of 95.56%, outperforming state-of-the-art methods

A Review of EMG Techniques for Detection of Gait Disorders

Electromyography (EMG) is a commonly used technique to record myoelectric signals, i.e., motor neuron signals that originate from the central nervous system (CNS) and synergistically activate groups of muscles resulting in movement. EMG patterns underlying movement, recorded using surface or needle electrodes, can be used to detect movement and gait abnormalities. In this review article, we examine EMG signal processing techniques that have been applied for diagnosing gait disorders. These techniques span from traditional statistical tests to complex machine learning algorithms. We particularly emphasize those techniques are promising for clinical applications. This study is pertinent to both medical and engineering research communities and is potentially helpful in advancing diagnostics and designing rehabilitation devices

A review of the effectiveness of lower limb orthoses used in cerebral palsy

To produce this review, a systematic literature search was conducted for relevant articles published in the period between the date of the previous ISPO consensus conference report on cerebral palsy (1994) and April 2008. The search terms were 'cerebral and pals* (palsy, palsies), 'hemiplegia', 'diplegia', 'orthos*' (orthoses, orthosis) orthot* (orthotic, orthotics), brace or AFO

Gait Recognition from Motion Capture Data

Gait recognition from motion capture data, as a pattern classification discipline, can be improved by the use of machine learning. This paper contributes to the state-of-the-art with a statistical approach for extracting robust gait features directly from raw data by a modification of Linear Discriminant Analysis with Maximum Margin Criterion. Experiments on the CMU MoCap database show that the suggested method outperforms thirteen relevant methods based on geometric features and a method to learn the features by a combination of Principal Component Analysis and Linear Discriminant Analysis. The methods are evaluated in terms of the distribution of biometric templates in respective feature spaces expressed in a number of class separability coefficients and classification metrics. Results also indicate a high portability of learned features, that means, we can learn what aspects of walk people generally differ in and extract those as general gait features. Recognizing people without needing group-specific features is convenient as particular people might not always provide annotated learning data. As a contribution to reproducible research, our evaluation framework and database have been made publicly available. This research makes motion capture technology directly applicable for human recognition.Comment: Preprint. Full paper accepted at the ACM Transactions on Multimedia Computing, Communications, and Applications (TOMM), special issue on Representation, Analysis and Recognition of 3D Humans. 18 pages. arXiv admin note: substantial text overlap with arXiv:1701.00995, arXiv:1609.04392, arXiv:1609.0693