Zero initialized active learning with spectral clustering using Hungarian method

Supervised machine learning tasks often require a large number of labeled training data to set up a model, and then prediction - for example the classification - is carried out based on this model. Nowadays tremendous amount of data is available on the web or in data warehouses, although only a portion of those data is annotated and the labeling process can be tedious, expensive and time consuming. Active learning tries to overcome this problem by reducing the labeling cost through allowing the learning system to iteratively select the data from which it learns. In special case of active learning, the process starts from zero initialized scenario, where the labeled training dataset is empty, and therefore only unsupervised methods can be performed. In this paper a novel query strategy framework is presented for this problem, called Clustering Based Balanced Sampling Framework (CBBSF), which is not only select the initial labeled training dataset, but uniformly selects the items among the categories to get a balanced labeled training dataset. The framework includes an assignment technique to implicitly determine the class membership probabilities. Assignment solution is updated during CBBSF iterations, hence it simulates supervised machine learning more accurately as the process progresses. The proposed Spectral Clustering Based Sampling (SCBS) query startegy realizes the CBBSF framework, and therefore it is applicable in the special zero initialized situation. This selection approach uses ClusterGAN (Clustering using Generative Adversarial Networks) integrated in the spectral clustering algorithm and then it selects an unlabeled instance depending on the class membership probabilities. Global and local versions of SCBS were developed, furthermore, most confident and minimal entropy measures were calculated, thus four different SCBS variants were examined in total. Experimental evaluation was conducted on the MNIST dataset, and the results showed that SCBS outperforms the state-of-the-art zero initialized active learning query strategies

Identification of functionally related enzymes by learning-to-rank methods

Enzyme sequences and structures are routinely used in the biological sciences as queries to search for functionally related enzymes in online databases. To this end, one usually departs from some notion of similarity, comparing two enzymes by looking for correspondences in their sequences, structures or surfaces. For a given query, the search operation results in a ranking of the enzymes in the database, from very similar to dissimilar enzymes, while information about the biological function of annotated database enzymes is ignored. In this work we show that rankings of that kind can be substantially improved by applying kernel-based learning algorithms. This approach enables the detection of statistical dependencies between similarities of the active cleft and the biological function of annotated enzymes. This is in contrast to search-based approaches, which do not take annotated training data into account. Similarity measures based on the active cleft are known to outperform sequence-based or structure-based measures under certain conditions. We consider the Enzyme Commission (EC) classification hierarchy for obtaining annotated enzymes during the training phase. The results of a set of sizeable experiments indicate a consistent and significant improvement for a set of similarity measures that exploit information about small cavities in the surface of enzymes

Convolutional Sparse Kernel Network for Unsupervised Medical Image Analysis

The availability of large-scale annotated image datasets and recent advances in supervised deep learning methods enable the end-to-end derivation of representative image features that can impact a variety of image analysis problems. Such supervised approaches, however, are difficult to implement in the medical domain where large volumes of labelled data are difficult to obtain due to the complexity of manual annotation and inter- and intra-observer variability in label assignment. We propose a new convolutional sparse kernel network (CSKN), which is a hierarchical unsupervised feature learning framework that addresses the challenge of learning representative visual features in medical image analysis domains where there is a lack of annotated training data. Our framework has three contributions: (i) We extend kernel learning to identify and represent invariant features across image sub-patches in an unsupervised manner. (ii) We initialise our kernel learning with a layer-wise pre-training scheme that leverages the sparsity inherent in medical images to extract initial discriminative features. (iii) We adapt a multi-scale spatial pyramid pooling (SPP) framework to capture subtle geometric differences between learned visual features. We evaluated our framework in medical image retrieval and classification on three public datasets. Our results show that our CSKN had better accuracy when compared to other conventional unsupervised methods and comparable accuracy to methods that used state-of-the-art supervised convolutional neural networks (CNNs). Our findings indicate that our unsupervised CSKN provides an opportunity to leverage unannotated big data in medical imaging repositories.Comment: Accepted by Medical Image Analysis (with a new title 'Convolutional Sparse Kernel Network for Unsupervised Medical Image Analysis'). The manuscript is available from following link (https://doi.org/10.1016/j.media.2019.06.005

A Meta-Learning Approach to One-Step Active Learning

We consider the problem of learning when obtaining the training labels is costly, which is usually tackled in the literature using active-learning techniques. These approaches provide strategies to choose the examples to label before or during training. These strategies are usually based on heuristics or even theoretical measures, but are not learned as they are directly used during training. We design a model which aims at \textit{learning active-learning strategies} using a meta-learning setting. More specifically, we consider a pool-based setting, where the system observes all the examples of the dataset of a problem and has to choose the subset of examples to label in a single shot. Experiments show encouraging results

Geometry meets semantics for semi-supervised monocular depth estimation

Depth estimation from a single image represents a very exciting challenge in computer vision. While other image-based depth sensing techniques leverage on the geometry between different viewpoints (e.g., stereo or structure from motion), the lack of these cues within a single image renders ill-posed the monocular depth estimation task. For inference, state-of-the-art encoder-decoder architectures for monocular depth estimation rely on effective feature representations learned at training time. For unsupervised training of these models, geometry has been effectively exploited by suitable images warping losses computed from views acquired by a stereo rig or a moving camera. In this paper, we make a further step forward showing that learning semantic information from images enables to improve effectively monocular depth estimation as well. In particular, by leveraging on semantically labeled images together with unsupervised signals gained by geometry through an image warping loss, we propose a deep learning approach aimed at joint semantic segmentation and depth estimation. Our overall learning framework is semi-supervised, as we deploy groundtruth data only in the semantic domain. At training time, our network learns a common feature representation for both tasks and a novel cross-task loss function is proposed. The experimental findings show how, jointly tackling depth prediction and semantic segmentation, allows to improve depth estimation accuracy. In particular, on the KITTI dataset our network outperforms state-of-the-art methods for monocular depth estimation.Comment: 16 pages, Accepted to ACCV 201