Visualizing and Predicting the Effects of Rheumatoid Arthritis on Hands

This dissertation was inspired by difficult decisions patients of chronic diseases have to make about about treatment options in light of uncertainty. We look at rheumatoid arthritis (RA), a chronic, autoimmune disease that primarily affects the synovial joints of the hands and causes pain and deformities. In this work, we focus on several parts of a computer-based decision tool that patients can interact with using gestures, ask questions about the disease, and visualize possible futures. We propose a hand gesture based interaction method that is easily setup in a doctor\u27s office and can be trained using a custom set of gestures that are least painful. Our system is versatile and can be used for operations like simple selections to navigating a 3D world. We propose a point distribution model (PDM) that is capable of modeling hand deformities that occur due to RA and a generalized fitting method for use on radiographs of hands. Using our shape model, we show novel visualization of disease progression. Using expertly staged radiographs, we propose a novel distance metric learning and embedding technique that can be used to automatically stage an unlabeled radiograph. Given a large set of expertly labeled radiographs, our data-driven approach can be used to extract different modes of deformation specific to a disease

Downstream Task Self-Supervised Learning for Object Recognition and Tracking

This dissertation addresses three limitations of deep learning methods in image and video understanding-based machine vision applications. Firstly, although deep convolutional neural networks (CNNs) are efficient for image recognition applications such as object detection and segmentation, they perform poorly under perspective distortions. In real-world applications, the camera perspective is a common problem that we can address by annotating large amounts of data, thus limiting the applicability of the deep learning models. Secondly, the typical approach for single-camera tracking problems is to use separate motion and appearance models, which are expensive in terms of computations and training data requirements. Finally, conventional multi-camera video understanding techniques use supervised learning algorithms to determine temporal relationships among objects. In large-scale applications, these methods are also limited by the requirement of extensive manually annotated data and computational resources.To address these limitations, we develop an uncertainty-aware self-supervised learning (SSL) technique that captures a model\u27s instance or semantic segmentation uncertainty from overhead images and guides the model to learn the impact of the new perspective on object appearance. The test-time data augmentation-based pseudo-label refinement technique continuously trains a model until convergence on new perspective images. The proposed method can be applied for both self-supervision and semi-supervision, thus increasing the effectiveness of a deep pre-trained model in new domains. Extensive experiments demonstrate the effectiveness of the SSL technique in both object detection and semantic segmentation problems. In video understanding applications, we introduce simultaneous segmentation and tracking as an unsupervised spatio-temporal latent feature clustering problem. The jointly learned multi-task features leverage the task-dependent uncertainty to generate discriminative features in multi-object videos. Experiments have shown that the proposed tracker outperforms several state-of-the-art supervised methods. Finally, we proposed an unsupervised multi-camera tracklet association (MCTA) algorithm to track multiple objects in real-time. MCTA leverages the self-supervised detector model for single-camera tracking and solves the multi-camera tracking problem using multiple pair-wise camera associations modeled as a connected graph. The graph optimization method generates a global solution for partially or fully overlapping camera networks

Landmarks Augmentation with Manifold-Barycentric Oversampling

The training of Generative Adversarial Networks (GANs) requires a large amount of data, stimulating the development of new augmentation methods to alleviate the challenge. Oftentimes, these methods either fail to produce enough new data or expand the dataset beyond the original manifold. In this paper, we propose a new augmentation method that guarantees to keep the new data within the original data manifold thanks to the optimal transport theory. The proposed algorithm finds cliques in the nearest-neighbors graph and, at each sampling iteration, randomly draws one clique to compute the Wasserstein barycenter with random uniform weights. These barycenters then become the new natural-looking elements that one could add to the dataset. We apply this approach to the problem of landmarks detection and augment the available annotation in both unpaired and in semi-supervised scenarios. Additionally, the idea is validated on cardiac data for the task of medical segmentation. Our approach reduces the overfitting and improves the quality metrics beyond the original data outcome and beyond the result obtained with popular modern augmentation methods.Comment: 11 pages, 4 figures, 3 tables. I.B. and N.B. contributed equally. D.V.D. is the corresponding autho

Graph Spectral Image Processing

Recent advent of graph signal processing (GSP) has spurred intensive studies of signals that live naturally on irregular data kernels described by graphs (e.g., social networks, wireless sensor networks). Though a digital image contains pixels that reside on a regularly sampled 2D grid, if one can design an appropriate underlying graph connecting pixels with weights that reflect the image structure, then one can interpret the image (or image patch) as a signal on a graph, and apply GSP tools for processing and analysis of the signal in graph spectral domain. In this article, we overview recent graph spectral techniques in GSP specifically for image / video processing. The topics covered include image compression, image restoration, image filtering and image segmentation

Deep Learning for Free-Hand Sketch: A Survey

Free-hand sketches are highly illustrative, and have been widely used by humans to depict objects or stories from ancient times to the present. The recent prevalence of touchscreen devices has made sketch creation a much easier task than ever and consequently made sketch-oriented applications increasingly popular. The progress of deep learning has immensely benefited free-hand sketch research and applications. This paper presents a comprehensive survey of the deep learning techniques oriented at free-hand sketch data, and the applications that they enable. The main contents of this survey include: (i) A discussion of the intrinsic traits and unique challenges of free-hand sketch, to highlight the essential differences between sketch data and other data modalities, e.g., natural photos. (ii) A review of the developments of free-hand sketch research in the deep learning era, by surveying existing datasets, research topics, and the state-of-the-art methods through a detailed taxonomy and experimental evaluation. (iii) Promotion of future work via a discussion of bottlenecks, open problems, and potential research directions for the community.Comment: This paper is accepted by IEEE TPAM