Fibre optic pressure sensors in healthcare applications

This PhD thesis provides an extensive description of the development of two fibre optic pressure sensors for applications in health care: (i) a miniature fibre optic Fabry–Perot pressure sensor for fluid pressure measurements in invasive blood pressure monitoring and; (ii) a highly sensitive fibre Bragg grating sensor for contact/interface pressure measurement. The fibre optic Fabry-Perot pressure sensor has a diameter of 125 μm and is created by forming a cavity at the tip of a single-mode optical fibre. Parylene films were used as the pressure-sensitive diaphragm. The performance of three sensors with different aspect ratios has been investigated. The pressure sensing range of ~10 kPa (diastolic pressure)- ~15 kPa (systolic pressure) was targeted; sensor with the cavity of 70 μm in diameter and cavity length of 87 μm is able to sense within a range of 0- 18 kPa with an average sensitivity of 0.12 nm/kPa and response time of 3 seconds. The temperature sensitivity of 0.084 nm/°C was observed. Hysteresis and wavelength drift were observed for the sensors, which may be due to the permeability of the Parylene film to the air. Solutions for reducing hysteresis, wavelength drift and temperature cross-sensitivity are discussed in detail. Fibre Bragg grating (FBG) sensor technology is an ideal candidate for contact pressure measurement in compression therapy, pressure ulcer or prosthetics due to its many advantages such as conforming to body parts, small size, biocompatibility and multiplexing capabilities. A successful mathematical model for an FBG contact pressure sensor for healthcare applications has been presented and experimentally validated. The model has been compared with previous studies reported in the literature and takes into account birefringence. The highest sensitivity was achieved for the disc shape with a sensitivity of 0.8719 nm/MPa for a diameter of 5.5 mm, thickness of 1 mm and Young’s modulus of 20 MPa. This sensor was comprised of a 3 mm long FBG 6 centrally located in the patch. This is a pressure sensitivity of ~270 times increase when compared with a bare FBG reported in the literature. Birefringence effect was observed for the disk patch for pressures larger than 2.6 MPa. Even though FBGs provide high sensitivity in contact pressure sensing in healthcare, the potential applications are limited by the size and cost of commercially available FBG interrogators. A successful first attempt towards the development of a single channel compact FBG interrogation was accomplished. The system consists of a three-section distributed Bragg Reflector (DBR) tuneable laser, microcontroller unit, precision 5 channel current driver IC, photodiode circuit and a temperature controller IC. The tuneable laser was calibrated within 1535-1544 nm wavelength range to produce three current–wavelength lookup tables for wavelength resolution of 1 nm, 0.1 nm, 0.01 nm which is dependent on the current resolution. Futureworkincludesaddingpowercircuitry, a photodiode circuit and a feedback circuit to minimize power fluctuations. The system was tested compared to the commercial Smartscope FBG interrogator

Fibre optic pressure sensors in healthcare applications

This PhD thesis provides an extensive description of the development of two fibre optic pressure sensors for applications in health care: (i) a miniature fibre optic Fabry–Perot pressure sensor for fluid pressure measurements in invasive blood pressure monitoring and; (ii) a highly sensitive fibre Bragg grating sensor for contact/interface pressure measurement. The fibre optic Fabry-Perot pressure sensor has a diameter of 125 μm and is created by forming a cavity at the tip of a single-mode optical fibre. Parylene films were used as the pressure-sensitive diaphragm. The performance of three sensors with different aspect ratios has been investigated. The pressure sensing range of ~10 kPa (diastolic pressure)- ~15 kPa (systolic pressure) was targeted; sensor with the cavity of 70 μm in diameter and cavity length of 87 μm is able to sense within a range of 0- 18 kPa with an average sensitivity of 0.12 nm/kPa and response time of 3 seconds. The temperature sensitivity of 0.084 nm/°C was observed. Hysteresis and wavelength drift were observed for the sensors, which may be due to the permeability of the Parylene film to the air. Solutions for reducing hysteresis, wavelength drift and temperature cross-sensitivity are discussed in detail. Fibre Bragg grating (FBG) sensor technology is an ideal candidate for contact pressure measurement in compression therapy, pressure ulcer or prosthetics due to its many advantages such as conforming to body parts, small size, biocompatibility and multiplexing capabilities. A successful mathematical model for an FBG contact pressure sensor for healthcare applications has been presented and experimentally validated. The model has been compared with previous studies reported in the literature and takes into account birefringence. The highest sensitivity was achieved for the disc shape with a sensitivity of 0.8719 nm/MPa for a diameter of 5.5 mm, thickness of 1 mm and Young’s modulus of 20 MPa. This sensor was comprised of a 3 mm long FBG 6 centrally located in the patch. This is a pressure sensitivity of ~270 times increase when compared with a bare FBG reported in the literature. Birefringence effect was observed for the disk patch for pressures larger than 2.6 MPa. Even though FBGs provide high sensitivity in contact pressure sensing in healthcare, the potential applications are limited by the size and cost of commercially available FBG interrogators. A successful first attempt towards the development of a single channel compact FBG interrogation was accomplished. The system consists of a three-section distributed Bragg Reflector (DBR) tuneable laser, microcontroller unit, precision 5 channel current driver IC, photodiode circuit and a temperature controller IC. The tuneable laser was calibrated within 1535-1544 nm wavelength range to produce three current–wavelength lookup tables for wavelength resolution of 1 nm, 0.1 nm, 0.01 nm which is dependent on the current resolution. Futureworkincludesaddingpowercircuitry, a photodiode circuit and a feedback circuit to minimize power fluctuations. The system was tested compared to the commercial Smartscope FBG interrogator

Surface Plasmon Resonance for Biosensing

The rise of photonics technologies has driven an extremely fast evolution in biosensing applications. Such rapid progress has created a gap of understanding and insight capability in the general public about advanced sensing systems that have been made progressively available by these new technologies. Thus, there is currently a clear need for moving the meaning of some keywords, such as plasmonic, into the daily vocabulary of a general audience with a reasonable degree of education. The selection of the scientific works reported in this book is carefully balanced between reviews and research papers and has the purpose of presenting a set of applications and case studies sufficiently broad enough to enlighten the reader attention toward the great potential of plasmonic biosensing and the great impact that can be expected in the near future for supporting disease screening and stratification

Recent Progress in Optical Fiber Research

This book presents a comprehensive account of the recent progress in optical fiber research. It consists of four sections with 20 chapters covering the topics of nonlinear and polarisation effects in optical fibers, photonic crystal fibers and new applications for optical fibers. Section 1 reviews nonlinear effects in optical fibers in terms of theoretical analysis, experiments and applications. Section 2 presents polarization mode dispersion, chromatic dispersion and polarization dependent losses in optical fibers, fiber birefringence effects and spun fibers. Section 3 and 4 cover the topics of photonic crystal fibers and a new trend of optical fiber applications. Edited by three scientists with wide knowledge and experience in the field of fiber optics and photonics, the book brings together leading academics and practitioners in a comprehensive and incisive treatment of the subject. This is an essential point of reference for researchers working and teaching in optical fiber technologies, and for industrial users who need to be aware of current developments in optical fiber research areas

Nanostructured piezoelectric materials for the design and development of self-sensing composite materials and energy harvesting devices

The work activities reported in this PhD thesis regard the functionalization of composite materials and the realization of energy harvesting devices by using nanostructured piezoelectric materials, which can be integrated in the composite without affecting its mechanical properties. The self-sensing composite materials were fabricated by interleaving between the plies of the laminate the piezoelectric elements. The problem of negatively impacting on the mechanical properties of the hosting structure was addressed by shaping the piezoelectric materials in appropriate ways. In the case of polymeric piezoelectric materials, the electrospinning technique allowed to produce highly-porous nanofibrous membranes which can be immerged in the hosting matrix without inducing delamination risk. The flexibility of the polymers was exploited also for the production of flexible tactile sensors. The sensing performances of the specimens were evaluated also in terms of lifetime with fatigue tests. In the case of ceramic piezo-materials, the production and the interleaving of nanometric piezoelectric powder limitedly affected the impact resistance of the laminate, which showed enhanced sensing properties. In addition to this, a model was proposed to predict the piezoelectric response of the self-sensing composite materials as function of the amount of the piezo-phase within the laminate and to adapt its sensing functionalities also for quasi-static loads. Indeed, one final application of the work was to integrate the piezoelectric nanofibers in the sole of a prosthetic foot in order to detect the walking cycle, which has a period in the order of 1 second. In the end, the energy harvesting capabilities of the piezoelectric materials were investigated, with the aim to design wearable devices able to collect energy from the environment and from the body movements. The research activities focused both on the power transfer capability to an external load and the charging of an energy storage unit, like, e.g., a supercapacitor

Applications of Antenna Technology in Sensors

During the past few decades, information technologies have been evolving at a tremendous rate, causing profound changes to our world and to our ways of living. Emerging applications have opened u[ new routes and set new trends for antenna sensors. With the advent of the Internet of Things (IoT), the adaptation of antenna technologies for sensor and sensing applications has become more important. Now, the antennas must be reconfigurable, flexible, low profile, and low-cost, for applications from airborne and vehicles, to machine-to-machine, IoT, 5G, etc. This reprint aims to introduce and treat a series of advanced and emerging topics in the field of antenna sensors

NASA SBIR abstracts of 1992, phase 1 projects

The objectives of 346 projects placed under contract by the Small Business Innovation Research (SBIR) program of the National Aeronautics and Space Administration (NASA) are described. These projects were selected competitively from among proposals submitted to NASA in response to the 1992 SBIR Program Solicitation. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 346, in order of its appearance in the body of the report. Appendixes to provide additional information about the SBIR program and permit cross-reference of the 1992 Phase 1 projects by company name, location by state, principal investigator, NASA Field Center responsible for management of each project, and NASA contract number are included

Integration of optical interconnections and optoelectronic components in flexible substrates

Licht als informatiedrager voor datacommunicatie kende een ongezien succes in de laatste decennia. Wegens de lage verliezen en hoge datasnelheden hebben ze voor het overbruggen van lange afstanden hun elektrische tegenhangers reeds geruime tijd verdrongen. Deze trend zet zich ook voort voor korte afstand communicatie op printplaten. Naast zijn functie als informatiedrager, wordt licht ook gebruikt om een waaier aan fysische grootheden te meten. Ook hier heeft licht enkele significante voordelen t.o.v elektrische informatiedragers, waardoor optische sensoren wijdverspreid zijn. Een tweede duidelijke trend binnen de elektronica is het gebruik van flexibele printkaarten. Deze zijn veel dunner, lichter en betrouwbaarder dan de klassieke harde printkaarten, waardoor ze uiterst geschikt zijn voor draagbare toepassingen waar compactheid en een laag gewicht hoge vereisten zijn. De flexibiliteit van de printplaten laat ook toe hen te gebruiken op onvlakke oppervlakken en op bewegende onderdelen. Het doel van het gepresenteerde doctoraatswerk is de ontwikkeling van een nieuw technologieplatform dat bovengenoemde trends combineert. Alle bouwblokken van optische communicatie, gaande van actieve opto-elektronische componenten, aanstuurelektronica, golfgeleiderbaantjes en galvanische verbindingen tot optische koppelstructuren tussen de verschillende bouwblokken, worden zodanig gerealiseerd dat elke component flexibel is en geïntegreerd wordt in een dunne folie met een dikte van slechts 150µm. Op die manier bekomen we een flexibele folie met alle passieve en actieve onderdelen voor optische communicatie geïntegreerd met enkel een elektrische interface naar de buitenwereld, wat de aanvaarding en toepassing van deze technologie in de huidige elektronica aanzienlijk kan versnellen. Binnen het doctoraatswerk werden alle voorgestelde technologieën en processen gerealiseerd en geoptimaliseerd. Bovendien werden de optische verliezen, warmteaspecten, hoogfrequent gedrag, mechanisch gedrag en betrouwbaarheid van de technologie gekarakteriseerd en vergeleken met de huidige state-of-the-art

Cumulative index to NASA Tech Briefs, 1986-1990, volumes 10-14

Tech Briefs are short announcements of new technology derived from the R&D activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This cumulative index of Tech Briefs contains abstracts and four indexes (subject, personal author, originating center, and Tech Brief number) and covers the period 1986 to 1990. The abstract section is organized by the following subject categories: electronic components and circuits, electronic systems, physical sciences, materials, computer programs, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences