Automated detection of brain abnormalities in neonatal hypoxia ischemic injury from MR images.

We compared the efficacy of three automated brain injury detection methods, namely symmetry-integrated region growing (SIRG), hierarchical region splitting (HRS) and modified watershed segmentation (MWS) in human and animal magnetic resonance imaging (MRI) datasets for the detection of hypoxic ischemic injuries (HIIs). Diffusion weighted imaging (DWI, 1.5T) data from neonatal arterial ischemic stroke (AIS) patients, as well as T2-weighted imaging (T2WI, 11.7T, 4.7T) at seven different time-points (1, 4, 7, 10, 17, 24 and 31 days post HII) in rat-pup model of hypoxic ischemic injury were used to assess the temporal efficacy of our computational approaches. Sensitivity, specificity, and similarity were used as performance metrics based on manual ('gold standard') injury detection to quantify comparisons. When compared to the manual gold standard, automated injury location results from SIRG performed the best in 62% of the data, while 29% for HRS and 9% for MWS. Injury severity detection revealed that SIRG performed the best in 67% cases while 33% for HRS. Prior information is required by HRS and MWS, but not by SIRG. However, SIRG is sensitive to parameter-tuning, while HRS and MWS are not. Among these methods, SIRG performs the best in detecting lesion volumes; HRS is the most robust, while MWS lags behind in both respects

Visual-hint Boundary to Segment Algorithm for Image Segmentation

Image segmentation has been a very active research topic in image analysis area. Currently, most of the image segmentation algorithms are designed based on the idea that images are partitioned into a set of regions preserving homogeneous intra-regions and inhomogeneous inter-regions. However, human visual intuition does not always follow this pattern. A new image segmentation method named Visual-Hint Boundary to Segment (VHBS) is introduced, which is more consistent with human perceptions. VHBS abides by two visual hint rules based on human perceptions: (i) the global scale boundaries tend to be the real boundaries of the objects; (ii) two adjacent regions with quite different colors or textures tend to result in the real boundaries between them. It has been demonstrated by experiments that, compared with traditional image segmentation method, VHBS has better performance and also preserves higher computational efficiency.Comment: 45 page

Flat zones filtering, connected operators, and filters by reconstruction

This correspondence deals with the notion of connected operators. Starting from the definition for operator acting on sets, it is shown how to extend it to operators acting on function. Typically, a connected operator acting on a function is a transformation that enlarges the partition of the space created by the flat zones of the functions. It is shown that from any connected operator acting on sets, one can construct a connected operator for functions (however, it is not the unique way of generating connected operators for functions). Moreover, the concept of pyramid is introduced in a formal way. It is shown that, if a pyramid is based on connected operators, the flat zones of the functions increase with the level of the pyramid. In other words, the flat zones are nested. Filters by reconstruction are defined and their main properties are presented. Finally, some examples of application of connected operators and use of flat zones are described.Peer ReviewedPostprint (published version

A Cosmic Watershed: the WVF Void Detection Technique

On megaparsec scales the Universe is permeated by an intricate filigree of clusters, filaments, sheets and voids, the Cosmic Web. For the understanding of its dynamical and hierarchical history it is crucial to identify objectively its complex morphological components. One of the most characteristic aspects is that of the dominant underdense Voids, the product of a hierarchical process driven by the collapse of minor voids in addition to the merging of large ones. In this study we present an objective void finder technique which involves a minimum of assumptions about the scale, structure and shape of voids. Our void finding method, the Watershed Void Finder (WVF), is based upon the Watershed Transform, a well-known technique for the segmentation of images. Importantly, the technique has the potential to trace the existing manifestations of a void hierarchy. The basic watershed transform is augmented by a variety of correction procedures to remove spurious structure resulting from sampling noise. This study contains a detailed description of the WVF. We demonstrate how it is able to trace and identify, relatively parameter free, voids and their surrounding (filamentary and planar) boundaries. We test the technique on a set of Kinematic Voronoi models, heuristic spatial models for a cellular distribution of matter. Comparison of the WVF segmentations of low noise and high noise Voronoi models with the quantitatively known spatial characteristics of the intrinsic Voronoi tessellation shows that the size and shape of the voids are succesfully retrieved. WVF manages to even reproduce the full void size distribution function.Comment: 24 pages, 15 figures, MNRAS accepted, for full resolution, see http://www.astro.rug.nl/~weygaert/tim1publication/watershed.pd