465 research outputs found

    Some results on injectivity and multistationarity in chemical reaction networks

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    The goal of this paper is to gather and develop some necessary and sufficient criteria for injectivity and multistationarity in vector fields associated with a chemical reaction network under a variety of more or less general assumptions on the nature of the network and the reaction rates. The results are primarily linear algebraic or matrix-theoretic, with some graph-theoretic results also mentioned. Several results appear in, or are close to, results in the literature. Here, we emphasise the connections between the results, and where possible, present elementary proofs which rely solely on basic linear algebra and calculus. A number of examples are provided to illustrate the variety of subtly different conclusions which can be reached via different computations. In addition, many of the computations are implemented in a web-based open source platform, allowing the reader to test examples including and beyond those analysed in the paper

    Development of overturning circulation in sloping waterbodies due to surface cooling

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    This work was supported by the Swiss National Science Foundation (project Buoyancy driven nearshore transport in lakes, HYPOlimnetic THErmal SIphonS, HYPOTHESIS, reference 175919) and by the Physics of Aquatic Systems Laboratory (APHYS), EPFL.Cooling the surface of freshwater bodies, whose temperatures are above the temperature of maximum density, can generate differential cooling between shallow and deep regions. When surface cooling occurs over a long enough period, the thermally induced cross-shore pressure gradient may drive an overturning circulation, a phenomenon called ‘thermal siphon’. However, the conditions under which this process begins are not yet fully characterised. Here, we examine the development of thermal siphons driven by a uniform loss of heat at the air–water interface in sloping, stratified basins. For a two-dimensional framework, we derive theoretical time and velocity scales associated with the transition from Rayleigh–Bénard type convection to a horizontal overturning circulation across the shallower sloping basin. This transition is characterised by a three-way horizontal momentum balance, in which the cross-shore pressure gradient balances the inertial terms before reaching a quasi-steady regime. We performed numerical and field experiments to test and show the robustness of the analytical scaling, describe the convective regimes and quantify the cross-shore transport induced by thermal siphons. Our results are relevant for understanding the nearshore fluid dynamics induced by nighttime or seasonal surface cooling in lakes and reservoirs.Swiss National Science Foundation (SNSF) European Commission 175919Physics of Aquatic Systems Laboratory (APHYS), EPF

    Some results on injectivity and multistationarity in chemical reaction networks

    Get PDF
    The goal of this paper is to gather and develop some necessary and sufficient criteria for injectivity and multistationarity in vector fields associated with a chemical reaction network under a variety of more or less general assumptions on the nature of the network and the reaction rates. The results are primarily linear algebraic or matrix-theoretic, with some graph-theoretic results also mentioned. Several results appear in, or are close to, results in the literature. Here, we emphasise the connections between the results, and where possible, present elementary proofs which rely solely on basic linear algebra and calculus. A number of examples are provided to illustrate the variety of subtly different conclusions which can be reached via different computations. In addition, many of the computations are implemented in a web-based open source platform, allowing the reader to test examples including and beyond those analysed in the paper

    Persistence and stability of generalized ribosome flow models with time-varying transition rates

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    In this paper the qualitative dynamical properties of so-called generalized ribosome flow models are studied. Ribosome flow models known from the literature are generalized by allowing an arbitrary directed network structure between the compartments and secondly, by assuming a general time-varying rate function describing the compartmental transitions. Persistence of the dynamics is shown using the chemical reaction network (CRN) representation of the system. We show the stability of different compartmental structures including strongly connected ones with an entropy-like logarithmic Lyapunov function. The L1 contractivity of solutions is also studied in the case of periodic reaction rates having the same period. It is also shown that different Lyapunov functions may be assigned to the same model depending on the factorization of the reaction rates.Comment: 28 pages, 8 figure
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