66 research outputs found

    Transactions of 2015 International Conference on Health Information Technology Advancement Vol.3, No. 1

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    The Third International Conference on Health Information Technology Advancement Kalamazoo, Michigan, October 30-31, 2015 Conference Chair Bernard Han, Ph.D., HIT Pro Department of Business Information Systems Haworth College of Business Western Michigan University Kalamazoo, MI 49008 Transactions Editor Dr. Huei Lee, Professor Department of Computer Information Systems Eastern Michigan University Ypsilanti, MI 48197 Volume 3, No. 1 Hosted by The Center for Health Information Technology Advancement, WM

    Machine Learning Based Characterization of preictal EEG

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    Convolutional neural networks (CNNs) that incorporate Long Short-term Memory (LSTM) have shown a great deal of success in recognizing preictal activity in electroencephalogram (EEG) analysis. It is postulated that the convolutional portion of the neural network (NN) is using some particular feature or set of features to determine this preictal state. In an attempt to gain a better understanding of these features, Gradient-weighted Class Activation Mapping (Grad-CAM) and augmented Gradient-weighted Class Activation Mapping (augmented Grad-CAM) are applied to the convolutional portion of patient specific neural networks trained to recognize preictal activity. While no particular set of features were consistently highlighted by augmented Grad-CAM, it was possible to discern that some EEG channels strongly influenced an EEG epoch as being correctly labeled as preictal

    Neonatal seizure detection based on single-channel EEG: instrumentation and algorithms

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    Seizure activity in the perinatal period, which constitutes the most common neurological emergency in the neonate, can cause brain disorders later in life or even death depending on their severity. This issue remains unsolved to date, despite the several attempts in tackling it using numerous methods. Therefore, a method is still needed that can enable neonatal cerebral activity monitoring to identify those at risk. Currently, electroencephalography (EEG) and amplitude-integrated EEG (aEEG) have been exploited for the identification of seizures in neonates, however both lack automation. EEG and aEEG are mainly visually analysed, requiring a specific skill set and as a result the presence of an expert on a 24/7 basis, which is not feasible. Additionally, EEG devices employed in neonatal intensive care units (NICU) are mainly designed around adults, meaning that their design specifications are not neonate specific, including their size due to multi-channel requirement in adults - adults minimum requirement is ≥ 32 channels, while gold standard in neonatal is equal to 10; they are bulky and occupy significant space in NICU. This thesis addresses the challenge of reliably, efficiently and effectively detecting seizures in the neonatal brain in a fully automated manner. Two novel instruments and two novel neonatal seizure detection algorithms (SDAs) are presented. The first instrument, named PANACEA, is a high-performance, wireless, wearable and portable multi-instrument, able to record neonatal EEG, as well as a plethora of (bio)signals. This device despite its high-performance characteristics and ability to record EEG, is mostly suggested to be used for the concurrent monitoring of other vital biosignals, such as electrocardiogram (ECG) and respiration, which provide vital information about a neonate's medical condition. The two aforementioned biosignals constitute two of the most important artefacts in the EEG and their concurrent acquisition benefit the SDA by providing information to an artefact removal algorithm. The second instrument, called neoEEG Board, is an ultra-low noise, wireless, portable and high precision neonatal EEG recording instrument. It is able to detect and record minute signals (< 10 nVp) enabling cerebral activity monitoring even from lower layers in the cortex. The neoEEG Board accommodates 8 inputs each one equipped with a patent-pending tunable filter topology, which allows passband formation based on the application. Both the PANACEA and the neoEEG Board are able to host low- to middle-complexity SDAs and they can operate continuously for at least 8 hours on 3-AA batteries. Along with PANACEA and the neoEEG Board, two novel neonatal SDAs have been developed. The first one, termed G prime-smoothed (G ́_s), is an on-line, automated, patient-specific, single-feature and single-channel EEG based SDA. The G ́_s SDA, is enabled by the invention of a novel feature, termed G prime (G ́) and can be characterised as an energy operator. The trace that the G ́_s creates, can also be used as a visualisation tool because of its distinct change at a presence of a seizure. Finally, the second SDA is machine learning (ML)-based and uses numerous features and a support vector machine (SVM) classifier. It can be characterised as automated, on-line and patient-independent, and similarly to G ́_s it makes use of a single-channel EEG. The proposed neonatal SDA introduces the use of the Hilbert-Huang transforms (HHT) in the field of neonatal seizure detection. The HHT analyses the non-linear and non-stationary EEG signal providing information for the signal as it evolves. Through the use of HHT novel features, such as the per intrinsic mode function (IMF) (0-3 Hz) sub-band power, were also employed. Detection rates of this novel neonatal SDA is comparable to multi-channel SDAs.Open Acces

    Identification of cardiac signals in ambulatory ECG data

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    The Electrocardiogram (ECG) is the primary tool for monitoring heart function. ECG signals contain vital information about the heart which informs diagnosis and treatment of cardiac conditions. The diagnosis of many cardiac arrhythmias require long term and continuous ECG data, often while the participant engages in activity. Wearable ambulatory ECG (AECG) systems, such as the common Holter system, allow heart monitoring for hours or days. The technological trajectory of AECG systems aims towards continuous monitoring during a wide range of activities with data processed locally in real time and transmitted to a monitoring centre for further analysis. Furthermore, hierarchical decision systems will allow wearable systems to produce alerts or even interventions. These functions could be integrated into smartphones.A fundamental limitation of this technology is the ability to identify heart signal characteristics in ECG signals contaminated with high amplitude and non-stationary noise. Noise processing become more severe as activity levels increase, and this is also when many heart problems are present.This thesis focuses on the identification of heart signals in AECG data recorded during participant activity. In particular, it explored ECG filters to identify major heart conditions in noisy AECG data. Gold standard methods use Extended Kalman filters with extrapolation based on sum of Gaussian models. New methods are developed using linear Kalman filtering and extrapolation based on a sum of Principal Component basis signals. Unlike the gold standard methods, extrapolation is heartcycle by heartcycle. Several variants are explored where basic signals span one or two heartcycles, and applied to single or multi-channel ECG data.The proposed methods are extensively tested against standard databases or normal and abnormal ECG data and the performance is compared to gold standard methods. Two performance metrics are used: improvement in signal to noise ratio and the observability of clinically important features in the heart signal. In all tests the proposed method performs better, and often significantly better, than the gold standard methods. It is demonstrated that abnormal ECG signals can be identified in noisy AECG data

    Predicting the Future is like Completing a Painting!

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    This article is an introductory work towards a larger research framework relative to Scientific Prediction. It is a mixed between science and philosophy of science, therefore we can talk about Experimental Philosophy of Science. As a first result, we introduce a new forecasting method based on image completion, named Forecasting Method by Image Inpainting (FM2I). In fact, time series forecasting is transformed into fully images- and signal-based processing procedures. After transforming a time series data into its corresponding image, the problem of data forecasting becomes essentially a problem of image inpainting problem, i.e., completing missing data in the image. An extensive experimental evaluation is conducted using a large dataset proposed by the well-known M3-competition. Results show that FM2I represents an efficient and robust tool for time series forecasting. It has achieved prominent results in terms of accuracy and outperforms the best M3 forecasting methods.Comment: 25 pages, 12 figure

    Texture and Colour in Image Analysis

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    Research in colour and texture has experienced major changes in the last few years. This book presents some recent advances in the field, specifically in the theory and applications of colour texture analysis. This volume also features benchmarks, comparative evaluations and reviews
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