A parallel Branch-and-Fix Coordination based matheuristic algorithm for solving large sized multistage stochastic mixed 0-1 problems

A parallel matheuristic algorithm is presented as a spin-off from the exact Branch-and-Fix Coordination (BFC) algorithm for solving multistage stochastic mixed 0-1 problems. Some steps to guarantee the solution’s optimality are relaxed in the BFC algorithm, such that an incomplete backward branching scheme is considered for solving large sized problems. Additionally, a new branching criterion is considered, based on dynamically-guided and stage-wise ordering schemes, such that fewer Twin Node Families are expected to be visited during the execution of the so-called H-DBFC algorithm. The inner parallelization IH-DBFC of the new approach, allows to solve in parallel scenario clusters MIP submodels at different steps of the algorithm. The outer parallel version, OH-DBFC, considers independent paths and allows iterative incumbent solution values exchanges to obtain tighter bounds of the solution value of the original problem. A broad computational experience is reported for assessing the quality of the matheuristic solution for large sized instances. The instances dimensions that are considered are up to two orders of magnitude larger than in some other works that we are aware of. The optimality gap of the H-DBFC solution value versus the one obtained by a state-of-the-artMIP solver is very small, if any. The new approach frequently outperforms it in terms of solution’s quality and computing time. A comparison with our Stochastic Dynamic Programming algorithm is also reported. The use of parallel computing provides, on one hand, a perspective for solving very large sized instances and, on the other hand, an expected large reduction in elapsed time.MTM2015-65317-P, MTM2015-63710-P, IT928-16; UFI BETS 2011; IZO-SGI SGIke

On parallel computing for stochastic optimization models and algorithms

167 p.Esta tesis tiene como objetivo principal la resolución de problemas de optimización bajo incertidumbre a gran escala, mediante la interconexión entre las disciplinas de Optimización estocástica y Computación en paralelo. Se describen algoritmos de descomposición desde la perspectivas de programación matemática y del aprovechamiento de recursos computacionales con el fin de resolver problemas de manera más rápida, de mayores dimensiones o/y obtener mejores resultados que sus técnicas homónimas en serie. Se han desarrollado dos estrategias de paralelización, denotadas como inner y outer. La primera de las cuales, realiza tareas en paralelo dentro de un esquema algorítmico en serie, mientras que la segunda ejecuta de manera simultánea y coordinada varios algoritmos secuenciales. La mayor descomposición del problema original, compartiendo el área de factibilidad, creando fases de sincronización y comunicación entre ejecuciones paralelas o definiendo condiciones iniciales divergentes, han sido claves en la eficacia de los diseños de los algoritmos propuestos. Como resultado, se presentan tanto algoritmos exactos como matheurísticos, que combinan metodologías metaheurísticas y técnicas de programación matemática. Se analiza la escalabilidad de cada algoritmo propuesto, y se consideran varios bancos de problemas de diferentes dimensiones, hasta un máximo de 58 millones de restricciones y 54 millones de variables (de las cuales 15 millones son binarias). La experiencia computacional ha sido principalmente realizada en el cluster ARINA de SGI/IZO-SGIker de la UPV/EHU

Applications of biased randomised algorithms and simheuristics to asset and liability management

Asset and Liability Management (ALM) has captured the attention of academics and financial researchers over the last few decades. On the one hand, we need to try to maximise our wealth by taking advantage of the financial market and, on the other hand, we need to cover our payments (liabilities) over time. The purpose of ALM is to give investors a series of resources or techniques to select the appropriate assets on the financial market that respond to the aforementioned two key factors: cover our liabilities and maximise our wealth. This thesis presents a set of techniques that are capable of tackling realistic financial problems without the usual requirement of considerable computational resources. These techniques are based on heuristics and simulation. Specifically, a biased randomised metaheuristic model is developed that has a direct application in the way insurance companies usually operate. The algorithm makes it possible to efficiently select the smallest number of assets, mainly fixed income, on the balance sheet while guaranteeing the company's obligations. This development allows for the incorporating of the credit quality of the issuer of the assets used. Likewise, a portfolio optimisation model with liabilities is developed and solved with a genetic algorithm. The portfolio optimisation problem differs from the usual one in that it is multi-period, and incorporates liabilities over time. Additionally, the possibility of external financing is included when the entity does not have sufficient cash. These conditions give rise to a complex problem that is efficiently solved by an evolutionary algorithm. In both cases, the algorithms are improved with the incorporation of Monte Carlo simulation. This allows the solutions to be robust when considering realistic market situations. The results are very promising. This research shows that simheuristics is an ideal method for this type of problem.La gestión de activos y pasivos (asset and liability management, ALM) ha acaparado la atención de académicos e investigadores financieros en las últimas décadas. Por un lado, debemos tratar de maximizar nuestra riqueza aprovechando el mercado financiero, y por otro, debemos cubrir nuestros pagos (pasivos) a lo largo del tiempo. El objetivo del ALM es dotar al inversor de una serie de recursos o técnicas para seleccionar los activos del mercado financiero adecuados para obedecer a los dos factores clave mencionados: cumplir con nuestros pasivos y maximizar nuestra riqueza. Esta tesis presenta un conjunto de técnicas que son capaces de abordar problemas financieros realistas sin la necesidad habitual de considerables recursos computacionales. Estas técnicas se basan en la heurística y la simulación. En concreto, se desarrolla un modelo metaheurístico sesgado que tiene una aplicación directa en la operación habitual de inmunización de las compañías de seguros. El algoritmo permite seleccionar eficientemente el menor número de activos, principalmente de renta fija, en el balance y garantizar las obligaciones de la compañía. Este desarrollo permite incorporar la calidad crediticia del emisor de los activos utilizados. Asimismo, se desarrolla un modelo de optimización de la cartera con el pasivo y se resuelve con un algoritmo genético. El problema de optimización de la cartera difiere del habitual en que es multiperiodo e incorpora los pasivos a lo largo del tiempo. Además, se incluye la posibilidad de financiación externa cuando la entidad no tiene suficiente efectivo. Estas condiciones dan lugar a un problema complejo que se resuelve eficientemente mediante un algoritmo evolutivo. En ambos casos, los algoritmos se mejoran con la incorporación de la simulación de Montecarlo. Esto permite que las soluciones sean robustas cuando consideramos situaciones de mercado realistas. Los resultados son muy prometedores. Esta investigación demuestra que la simheurística es un método ideal para este tipo de problemas.La gestió d'actius i passius (asset and liability management, ALM) ha acaparat l'atenció d'acadèmics i investigadors financers les darreres dècades. D'una banda, hem de mirar de maximitzar la nostra riquesa aprofitant el mercat financer, i de l'altra, hem de cobrir els nostres pagaments (passius) al llarg del temps. L'objectiu de l'ALM és dotar l'inversor d'una sèrie de recursos o tècniques per seleccionar els actius del mercat financer adequats per obeir als dos factors clau esmentats: complir els passius i maximitzar la nostra riquesa. Aquesta tesi presenta un conjunt de tècniques que són capaces d'abordar problemes financers realistes sense la necessitat habitual de recursos computacionals considerables. Aquestes tècniques es basen en l'heurística i la simulació. En concret, es desenvolupa un model metaheurístic esbiaixat que té una aplicació directa a l'operació habitual d'immunització de les companyies d'assegurances. L'algorisme permet seleccionar eficientment el menor nombre d'actius, principalment de renda fixa, al balanç i garantir les obligacions de la companyia. Aquest desenvolupament permet incorporar la qualitat creditícia de l'emissor dels actius utilitzats. Així mateix, es desenvolupa un model d'optimització de la cartera amb el passiu i es resol amb un algorisme genètic. El problema d'optimització de la cartera difereix de l'habitual en el fet que és multiperíode i incorpora els passius al llarg del temps. A més, s'inclou la possibilitat de finançament extern quan l'entitat no té prou efectiu. Aquestes condicions donen lloc a un problema complex que es resol eficientment mitjançant un algorisme evolutiu. En tots dos casos, els algorismes es milloren amb la incorporació de la simulació de Montecarlo. Això permet que les solucions siguin robustes quan considerem situacions de mercat realistes. Els resultats són molt prometedors. Aquesta recerca demostra que la simheurística és un mètode ideal per a aquesta mena de problemes.Tecnologías de la información y de rede

Models and Algorithms for the Optimisation of Replenishment, Production and Distribution Plans in Industrial Enterprises

Tesis por compendio[ES] La optimización en las empresas manufactureras es especialmente importante, debido a las grandes inversiones que realizan, ya que a veces estas inversiones no obtienen el rendimiento esperado porque los márgenes de beneficio de los productos son muy ajustados. Por ello, las empresas tratan de maximizar el uso de los recursos productivos y financieros minimizando el tiempo perdido y, al mismo tiempo, mejorando los flujos de los procesos y satisfaciendo las necesidades del mercado. El proceso de planificación es una actividad crítica para las empresas. Esta tarea implica grandes retos debido a los cambios del mercado, las alteraciones en los procesos de producción dentro de la empresa y en la cadena de suministro, y los cambios en la legislación, entre otros. La planificación del aprovisionamiento, la producción y la distribución desempeña un papel fundamental en el rendimiento de las empresas manufactureras, ya que una planificación ineficaz de los proveedores, los procesos de producción y los sistemas de distribución contribuye a aumentar los costes de los productos, a alargar los plazos de entrega y a reducir los beneficios. La planificación eficaz es un proceso complejo que abarca una amplia gama de actividades para garantizar que los equipos, los materiales y los recursos humanos estén disponibles en el momento y el lugar adecuados. Motivados por la complejidad de la planificación en las empresas manufactureras, esta tesis estudia y desarrolla herramientas cuantitativas para ayudar a los planificadores en los procesos de la planificación del aprovisionamiento, producción y distribución. Desde esta perspectiva, se proponen modelos realistas y métodos eficientes para apoyar la toma de decisiones en las empresas industriales, principalmente en las pequeñas y medianas empresas (PYMES). Las aportaciones de esta tesis suponen un avance científico basado en una exhaustiva revisión bibliográfica sobre la planificación del aprovisionamiento, la producción y la distribución que ayuda a comprender los principales modelos y algoritmos utilizados para resolver estos planes, y pone en relieve las tendencias y las futuras direcciones de investigación. También proporciona un marco holístico para caracterizar los modelos y algoritmos centrándose en la planificación de la producción, la programación y la secuenciación. Esta tesis también propone una herramienta de apoyo a la decisión para seleccionar un algoritmo o método de solución para resolver problemas concretos de la planificación del aprovisionamiento, producción y distribución en función de su complejidad, lo que permite a los planificadores no duplicar esfuerzos de modelización o programación de técnicas de solución. Por último, se desarrollan nuevos modelos matemáticos y enfoques de solución de última generación, como los algoritmos matheurísticos, que combinan la programación matemática y las técnicas metaheurísticas. Los nuevos modelos y algoritmos comprenden mejoras en términos de rendimiento computacional, e incluyen características realistas de los problemas del mundo real a los que se enfrentan las empresas de fabricación. Los modelos matemáticos han sido validados con un caso de una importante empresa del sector de la automoción en España, lo que ha permitido evaluar la relevancia práctica de estos novedosos modelos utilizando instancias de gran tamaño, similares a las existentes en la empresa objeto de estudio. Además, los algoritmos matheurísticos han sido probados utilizando herramientas libres y de código abierto. Esto también contribuye a la práctica de la investigación operativa, y proporciona una visión de cómo desplegar estos métodos de solución y el tiempo de cálculo y rendimiento de la brecha que se puede obtener mediante el uso de software libre o de código abierto.[CA] L'optimització a les empreses manufactureres és especialment important, a causa de les grans inversions que realitzen, ja que de vegades aquestes inversions no obtenen el rendiment esperat perquè els marges de benefici dels productes són molt ajustats. Per això, les empreses intenten maximitzar l'ús dels recursos productius i financers minimitzant el temps perdut i, alhora, millorant els fluxos dels processos i satisfent les necessitats del mercat. El procés de planificació és una activitat crítica per a les empreses. Aquesta tasca implica grans reptes a causa dels canvis del mercat, les alteracions en els processos de producció dins de l'empresa i la cadena de subministrament, i els canvis en la legislació, entre altres. La planificació de l'aprovisionament, la producció i la distribució té un paper fonamental en el rendiment de les empreses manufactureres, ja que una planificació ineficaç dels proveïdors, els processos de producció i els sistemes de distribució contribueix a augmentar els costos dels productes, allargar els terminis de lliurament i reduir els beneficis. La planificació eficaç és un procés complex que abasta una àmplia gamma d'activitats per garantir que els equips, els materials i els recursos humans estiguen disponibles al moment i al lloc adequats. Motivats per la complexitat de la planificació a les empreses manufactureres, aquesta tesi estudia i desenvolupa eines quantitatives per ajudar als planificadors en els processos de la planificació de l'aprovisionament, producció i distribució. Des d'aquesta perspectiva, es proposen models realistes i mètodes eficients per donar suport a la presa de decisions a les empreses industrials, principalment a les petites i mitjanes empreses (PIMES). Les aportacions d'aquesta tesi suposen un avenç científic basat en una exhaustiva revisió bibliogràfica sobre la planificació de l'aprovisionament, la producció i la distribució que ajuda a comprendre els principals models i algorismes utilitzats per resoldre aquests plans, i posa de relleu les tendències i les futures direccions de recerca. També proporciona un marc holístic per caracteritzar els models i algorismes centrant-se en la planificació de la producció, la programació i la seqüenciació. Aquesta tesi també proposa una eina de suport a la decisió per seleccionar un algorisme o mètode de solució per resoldre problemes concrets de la planificació de l'aprovisionament, producció i distribució en funció de la seua complexitat, cosa que permet als planificadors no duplicar esforços de modelització o programació de tècniques de solució. Finalment, es desenvolupen nous models matemàtics i enfocaments de solució d'última generació, com ara els algoritmes matheurístics, que combinen la programació matemàtica i les tècniques metaheurístiques. Els nous models i algoritmes comprenen millores en termes de rendiment computacional, i inclouen característiques realistes dels problemes del món real a què s'enfronten les empreses de fabricació. Els models matemàtics han estat validats amb un cas d'una important empresa del sector de l'automoció a Espanya, cosa que ha permés avaluar la rellevància pràctica d'aquests nous models utilitzant instàncies grans, similars a les existents a l'empresa objecte d'estudi. A més, els algorismes matheurístics han estat provats utilitzant eines lliures i de codi obert. Això també contribueix a la pràctica de la investigació operativa, i proporciona una visió de com desplegar aquests mètodes de solució i el temps de càlcul i rendiment de la bretxa que es pot obtindre mitjançant l'ús de programari lliure o de codi obert.[EN] Optimisation in manufacturing companies is especially important, due to the large investments they make, as sometimes these investments do not obtain the expected return because the profit margins of products are very tight. Therefore, companies seek to maximise the use of productive and financial resources by minimising lost time and, at the same time, improving process flows while meeting market needs. The planning process is a critical activity for companies. This task involves great challenges due to market changes, alterations in production processes within the company and in the supply chain, and changes in legislation, among others. Planning of replenishment, production and distribution plays a critical role in the performance of manufacturing companies because ineffective planning of suppliers, production processes and distribution systems contributes to higher product costs, longer lead times and less profits. Effective planning is a complex process that encompasses a wide range of activities to ensure that equipment, materials and human resources are available in the right time and the right place. Motivated by the complexity of planning in manufacturing companies, this thesis studies and develops quantitative tools to help planners in the replenishment, production and delivery planning processes. From this perspective, realistic models and efficient methods are proposed to support decision making in industrial companies, mainly in small- and medium-sized enterprises (SMEs). The contributions of this thesis represent a scientific breakthrough based on a comprehensive literature review about replenishment, production and distribution planning that helps to understand the main models and algorithms used to solve these plans, and highlights trends and future research directions. It also provides a holistic framework to characterise models and algorithms by focusing on production planning, scheduling and sequencing. This thesis also proposes a decision support tool for selecting an algorithm or solution method to solve concrete replenishment, production and distribution planning problems according to their complexity, which allows planners to not duplicate efforts modelling or programming solution techniques. Finally, new state-of-the-art mathematical models and solution approaches are developed, such as matheuristic algorithms, which combine mathematical programming and metaheuristic techniques. The new models and algorithms comprise improvements in computational performance terms, and include realistic features of real-world problems faced by manufacturing companies. The mathematical models have been validated with a case of an important company in the automotive sector in Spain, which allowed to evaluate the practical relevance of these novel models using large instances, similarly to those existing in the company under study. In addition, the matheuristic algorithms have been tested using free and open-source tools. This also helps to contribute to the practice of operations research, and provides insight into how to deploy these solution methods and the computational time and gap performance that can be obtained by using free or open-source software.This work would not have been possible without the following funding sources: Conselleria de Educación, Investigación, Cultura y Deporte, Generalitat Valenciana for hiring predoctoral research staff with Grant (ACIF/2018/170) and the European Social Fund with the Grant Operational Programme of FSE 2014-2020. Conselleria de Educación, Investigación, Cultura y Deporte, Generalitat Valenciana for predoctoral contract students to stay in research centers outside the research centers outside the Valencian Community (BEFPI/2021/040) and the European Social Fund.Guzmán Ortiz, BE. (2022). Models and Algorithms for the Optimisation of Replenishment, Production and Distribution Plans in Industrial Enterprises [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/187461Compendi

Essays on Multistage Stochastic Programming applied to Asset Liability Management

Uncertainty is a key element of reality. Thus, it becomes natural that the search for methods allows us to represent the unknown in mathematical terms. These problems originate a large class of probabilistic programs recognized as stochastic programming models. They are more realistic than deterministic ones, and their aim is to incorporate uncertainty into their definitions. This dissertation approaches the probabilistic problem class of multistage stochastic problems with chance constraints and joint-chance constraints. Initially, we propose a multistage stochastic asset liability management (ALM) model for a Brazilian pension fund industry. Our model is formalized in compliance with the Brazilian laws and policies. Next, given the relevance of the input parameters for these optimization models, we turn our attention to different sampling models, which compose the discretization process of these stochastic models. We check how these different sampling methodologies impact on the final solution and the portfolio allocation, outlining good options for ALM models. Finally, we propose a framework for the scenario-tree generation and optimization of multistage stochastic programming problems. Relying on the Knuth transform, we generate the scenario trees, taking advantage of the left-child, right-sibling representation, which makes the simulation more efficient in terms of time and the number of scenarios. We also formalize an ALM model reformulation based on implicit extensive form for the optimization model. This technique is designed by the definition of a filtration process with bundles, and coded with the support of an algebraic modeling language. The efficiency of this methodology is tested in a multistage stochastic ALM model with joint-chance constraints. Our framework makes it possible to reach the optimal solution for trees with a reasonable number of scenarios.A incerteza é um elemento fundamental da realidade. Então, torna-se natural a busca por métodos que nos permitam representar o desconhecido em termos matemáticos. Esses problemas originam uma grande classe de programas probabilísticos reconhecidos como modelos de programação estocástica. Eles são mais realísticos que os modelos determinísticos, e tem por objetivo incorporar a incerteza em suas definições. Essa tese aborda os problemas probabilísticos da classe de problemas de multi-estágio com incerteza e com restrições probabilísticas e com restrições probabilísticas conjuntas. Inicialmente, nós propomos um modelo de administração de ativos e passivos multi-estágio estocástico para a indústria de fundos de pensão brasileira. Nosso modelo é formalizado em conformidade com a leis e políticas brasileiras. A seguir, dada a relevância dos dados de entrada para esses modelos de otimização, tornamos nossa atenção às diferentes técnicas de amostragem. Elas compõem o processo de discretização desses modelos estocásticos Nós verificamos como as diferentes metodologias de amostragem impactam a solução final e a alocação do portfólio, destacando boas opções para modelos de administração de ativos e passivos. Finalmente, nós propomos um “framework” para a geração de árvores de cenário e otimização de modelos com incerteza multi-estágio. Baseados na tranformação de Knuth, nós geramos a árvore de cenários considerando a representação filho-esqueda, irmão-direita o que torna a simulação mais eficiente em termos de tempo e de número de cenários. Nós também formalizamos uma reformulação do modelo de administração de ativos e passivos baseada na abordagem extensiva implícita para o modelo de otimização. Essa técnica é projetada pela definição de um processo de filtragem com “bundles”; e codifciada com o auxílio de uma linguagem de modelagem algébrica. A eficiência dessa metodologia é testada em um modelo de administração de ativos e passivos com incerteza com restrições probabilísticas conjuntas. Nosso framework torna possível encontrar a solução ótima para árvores com um número razoável de cenários

A decomposition strategy for decision problems with endogenous uncertainty using mixed-integer programming

Despite methodological advances for modeling decision problems under uncertainty, faithfully representing endogenous uncertainty still proves challenging, both in terms of modeling capabilities and computational requirements. A novel framework called Decision Programming provides an approach for solving such decision problems using off-the-shelf mathematical optimization solvers. This is made possible by using influence diagrams to represent a given decision problem, which is then formulated as a mixed-integer linear programming problem. In this paper, we focus on the type of endogenous uncertainty that received less attention in the introduction of Decision Programming: conditionally observed information. Multi-stage stochastic programming (MSSP) models use conditional non-anticipativity constraints (C-NACs) to represent such uncertainties, and we show how such constraints can be incorporated into Decision Programming models. This allows us to consider the two main types of endogenous uncertainty simultaneously, namely decision-dependent information structure and decision-dependent probability distribution. Additionally, we present a decomposition approach that provides significant computational savings and also enables considering continuous decision variables in certain parts of the problem, whereas the original formulation was restricted to discrete variables only. The extended framework is illustrated with two example problems. The first considers an illustrative multiperiod game and the second is a large-scale cost-benefit problem regarding climate change mitigation. Neither of these example problems could be solved with existing frameworks.Comment: 26 pages, 10 figure

Operational Research: Methods and Applications

Throughout its history, Operational Research has evolved to include a variety of methods, models and algorithms that have been applied to a diverse and wide range of contexts. This encyclopedic article consists of two main sections: methods and applications. The first aims to summarise the up-to-date knowledge and provide an overview of the state-of-the-art methods and key developments in the various subdomains of the field. The second offers a wide-ranging list of areas where Operational Research has been applied. The article is meant to be read in a nonlinear fashion. It should be used as a point of reference or first-port-of-call for a diverse pool of readers: academics, researchers, students, and practitioners. The entries within the methods and applications sections are presented in alphabetical order. The authors dedicate this paper to the 2023 Turkey/Syria earthquake victims. We sincerely hope that advances in OR will play a role towards minimising the pain and suffering caused by this and future catastrophes

Operational research:methods and applications

Throughout its history, Operational Research has evolved to include a variety of methods, models and algorithms that have been applied to a diverse and wide range of contexts. This encyclopedic article consists of two main sections: methods and applications. The first aims to summarise the up-to-date knowledge and provide an overview of the state-of-the-art methods and key developments in the various subdomains of the field. The second offers a wide-ranging list of areas where Operational Research has been applied. The article is meant to be read in a nonlinear fashion. It should be used as a point of reference or first-port-of-call for a diverse pool of readers: academics, researchers, students, and practitioners. The entries within the methods and applications sections are presented in alphabetical order

Fuelling the zero-emissions road freight of the future: routing of mobile fuellers

The future of zero-emissions road freight is closely tied to the sufficient availability of new and clean fuel options such as electricity and Hydrogen. In goods distribution using Electric Commercial Vehicles (ECVs) and Hydrogen Fuel Cell Vehicles (HFCVs) a major challenge in the transition period would pertain to their limited autonomy and scarce and unevenly distributed refuelling stations. One viable solution to facilitate and speed up the adoption of ECVs/HFCVs by logistics, however, is to get the fuel to the point where it is needed (instead of diverting the route of delivery vehicles to refuelling stations) using "Mobile Fuellers (MFs)". These are mobile battery swapping/recharging vans or mobile Hydrogen fuellers that can travel to a running ECV/HFCV to provide the fuel they require to complete their delivery routes at a rendezvous time and space. In this presentation, new vehicle routing models will be presented for a third party company that provides MF services. In the proposed problem variant, the MF provider company receives routing plans of multiple customer companies and has to design routes for a fleet of capacitated MFs that have to synchronise their routes with the running vehicles to deliver the required amount of fuel on-the-fly. This presentation will discuss and compare several mathematical models based on different business models and collaborative logistics scenarios

Multi-stage stochastic optimization and reinforcement learning for forestry epidemic and covid-19 control planning

This dissertation focuses on developing new modeling and solution approaches based on multi-stage stochastic programming and reinforcement learning for tackling biological invasions in forests and human populations. Emerald Ash Borer (EAB) is the nemesis of ash trees. This research introduces a multi-stage stochastic mixed-integer programming model to assist forest agencies in managing emerald ash borer insects throughout the U.S. and maximize the public benets of preserving healthy ash trees. This work is then extended to present the first risk-averse multi-stage stochastic mixed-integer program in the invasive species management literature to account for extreme events. Significant computational achievements are obtained using a scenario dominance decomposition and cutting plane algorithm.The results of this work provide crucial insights and decision strategies for optimal resource allocation among surveillance, treatment, and removal of ash trees, leading to a better and healthier environment for future generations. This dissertation also addresses the computational difficulty of solving one of the most difficult classes of combinatorial optimization problems, the Multi-Dimensional Knapsack Problem (MKP). A novel 2-Dimensional (2D) deep reinforcement learning (DRL) framework is developed to represent and solve combinatorial optimization problems focusing on MKP. The DRL framework trains different agents for making sequential decisions and finding the optimal solution while still satisfying the resource constraints of the problem. To our knowledge, this is the first DRL model of its kind where a 2D environment is formulated, and an element of the DRL solution matrix represents an item of the MKP. Our DRL framework shows that it can solve medium-sized and large-sized instances at least 45 and 10 times faster in CPU solution time, respectively, with a maximum solution gap of 0.28% compared to the solution performance of CPLEX. Applying this methodology, yet another recent epidemic problem is tackled, that of COVID-19. This research investigates a reinforcement learning approach tailored with an agent-based simulation model to simulate the disease growth and optimize decision-making during an epidemic. This framework is validated using the COVID-19 data from the Center for Disease Control and Prevention (CDC). Research results provide important insights into government response to COVID-19 and vaccination strategies