Efficient Two-Stage Group Testing Algorithms for Genetic Screening

Efficient two-stage group testing algorithms that are particularly suited for rapid and less-expensive DNA library screening and other large scale biological group testing efforts are investigated in this paper. The main focus is on novel combinatorial constructions in order to minimize the number of individual tests at the second stage of a two-stage disjunctive testing procedure. Building on recent work by Levenshtein (2003) and Tonchev (2008), several new infinite classes of such combinatorial designs are presented.Comment: 14 pages; to appear in "Algorithmica". Part of this work has been presented at the ICALP 2011 Group Testing Workshop; arXiv:1106.368

New Combinatorial Construction Techniques for Low-Density Parity-Check Codes and Systematic Repeat-Accumulate Codes

This paper presents several new construction techniques for low-density parity-check (LDPC) and systematic repeat-accumulate (RA) codes. Based on specific classes of combinatorial designs, the improved code design focuses on high-rate structured codes with constant column weights 3 and higher. The proposed codes are efficiently encodable and exhibit good structural properties. Experimental results on decoding performance with the sum-product algorithm show that the novel codes offer substantial practical application potential, for instance, in high-speed applications in magnetic recording and optical communications channels.Comment: 10 pages; to appear in "IEEE Transactions on Communications

A tripling construction for overlarge sets of KTS

AbstractAn overlarge set of KTS(v), denoted by OLKTS(v), is a collection {(X∖{x},Bx):x∈X}, where X is a (v+1)-set, each (X∖{x},Bx) is a KTS(v) and {Bx:x∈X} forms a partition of all triples on X. In this paper, we give a tripling construction for overlarge sets of KTS. Our main result is that: If there exists an OLKTS(v) with a special property, then there exists an OLKTS(3v). It is obtained that there exists an OLKTS(3m(2u+1)) for u=22n−1−1 or u=qn, where prime power q≡7 (mod 12) and m≥0,n≥1

A quasidouble of the affine plane of order 4 and the solution of a problem on additive designs

A 2-(v,k,λ) block design (P,B) is additive if, up to isomorphism, P can be represented as a subset of a commutative group (G,+) in such a way that the k elements of each block in B sum up to zero in G. If, for some suitable G, the embedding of P in G is also such that, conversely, any zero-sum k-subset of P is a block in B, then (P,B) is said to be strongly additive. In this paper we exhibit the very first examples of additive 2-designs that are not strongly additive, thereby settling an open problem posed in 2019. Our main counterexample is a resolvable 2-(16,4,2) design (F_4×F_4, B_2), which decomposes into two disjoint isomorphic copies of the affine plane of order four. An essential part of our construction is a (cyclic) decomposition of the point-plane design of AG(4,2) into seven disjoint isomorphic copies of the affine plane of order four. This produces, in addition, a solution to Kirkman's schoolgirl problem

Frequency permutation arrays

Motivated by recent interest in permutation arrays, we introduce and investigate the more general concept of frequency permutation arrays (FPAs). An FPA of length n=m lambda and distance d is a set T of multipermutations on a multiset of m symbols, each repeated with frequency lambda, such that the Hamming distance between any distinct x,y in T is at least d. Such arrays have potential applications in powerline communication. In this paper, we establish basic properties of FPAs, and provide direct constructions for FPAs using a range of combinatorial objects, including polynomials over finite fields, combinatorial designs, and codes. We also provide recursive constructions, and give bounds for the maximum size of such arrays.Comment: To appear in Journal of Combinatorial Design

Constructions of General Covering Designs

Given five positive integers $v, m,k,\lambda$ and $t$ where $v \geq k \geq t$ and $v \geq m \geq t,$ a $t$-$(v,k,m,\lambda)$ general covering design is a pair $(X,\mathcal{B})$ where $X$ is a set of $v$ elements (called points) and $\mathcal{B}$ a multiset of $k$-subsets of $X$ (called blocks) such that every $m$-subset of $X$ intersects (is covered by) at least $\lambda$ members of $\mathcal{B}$ in at least $t$ points. In this article we present new constructions for general covering designs and we generalize some others. By means of these constructions we will be able to obtain some new upper bounds on the minimum size of such designs.Comment: Section 3.2 revised and extended; plus some re-editing throughou