78 research outputs found
Comprehensive Taxonomies of Nature- and Bio-inspired Optimization: Inspiration versus Algorithmic Behavior, Critical Analysis and Recommendations
In recent years, a great variety of nature- and bio-inspired algorithms has
been reported in the literature. This algorithmic family simulates different
biological processes observed in Nature in order to efficiently address complex
optimization problems. In the last years the number of bio-inspired
optimization approaches in literature has grown considerably, reaching
unprecedented levels that dark the future prospects of this field of research.
This paper addresses this problem by proposing two comprehensive,
principle-based taxonomies that allow researchers to organize existing and
future algorithmic developments into well-defined categories, considering two
different criteria: the source of inspiration and the behavior of each
algorithm. Using these taxonomies we review more than three hundred
publications dealing with nature-inspired and bio-inspired algorithms, and
proposals falling within each of these categories are examined, leading to a
critical summary of design trends and similarities between them, and the
identification of the most similar classical algorithm for each reviewed paper.
From our analysis we conclude that a poor relationship is often found between
the natural inspiration of an algorithm and its behavior. Furthermore,
similarities in terms of behavior between different algorithms are greater than
what is claimed in their public disclosure: specifically, we show that more
than one-third of the reviewed bio-inspired solvers are versions of classical
algorithms. Grounded on the conclusions of our critical analysis, we give
several recommendations and points of improvement for better methodological
practices in this active and growing research field.Comment: 76 pages, 6 figure
Ultra-high-speed imaging of bubbles interacting with cells and tissue
Ultrasound contrast microbubbles are exploited in molecular imaging, where bubbles are directed to target cells and where their high-scattering cross section to ultrasound allows for the detection of pathologies at a molecular level. In therapeutic applications vibrating bubbles close to cells may alter the permeability of cell membranes, and these systems are therefore highly interesting for drug and gene delivery applications using ultrasound. In a more extreme regime bubbles are driven through shock waves to sonoporate or kill cells through intense stresses or jets following inertial bubble collapse. Here, we elucidate some of the underlying mechanisms using the 25-Mfps camera Brandaris128, resolving the bubble dynamics and its interactions with cells. We quantify acoustic microstreaming around oscillating bubbles close to rigid walls and evaluate the shear stresses on nonadherent cells. In a study on the fluid dynamical interaction of cavitation bubbles with adherent cells, we find that the nonspherical collapse of bubbles is responsible for cell detachment. We also visualized the dynamics of vibrating microbubbles in contact with endothelial cells followed by fluorescent imaging of the transport of propidium iodide, used as a membrane integrity probe, into these cells showing a direct correlation between cell deformation and cell membrane permeability
Emerging Trends in Mechatronics
Mechatronics is a multidisciplinary branch of engineering combining mechanical, electrical and electronics, control and automation, and computer engineering fields. The main research task of mechatronics is design, control, and optimization of advanced devices, products, and hybrid systems utilizing the concepts found in all these fields. The purpose of this special issue is to help better understand how mechatronics will impact on the practice and research of developing advanced techniques to model, control, and optimize complex systems. The special issue presents recent advances in mechatronics and related technologies. The selected topics give an overview of the state of the art and present new research results and prospects for the future development of the interdisciplinary field of mechatronic systems
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