6,268 research outputs found
Multilevel Weighted Support Vector Machine for Classification on Healthcare Data with Missing Values
This work is motivated by the needs of predictive analytics on healthcare
data as represented by Electronic Medical Records. Such data is invariably
problematic: noisy, with missing entries, with imbalance in classes of
interests, leading to serious bias in predictive modeling. Since standard data
mining methods often produce poor performance measures, we argue for
development of specialized techniques of data-preprocessing and classification.
In this paper, we propose a new method to simultaneously classify large
datasets and reduce the effects of missing values. It is based on a multilevel
framework of the cost-sensitive SVM and the expected maximization imputation
method for missing values, which relies on iterated regression analyses. We
compare classification results of multilevel SVM-based algorithms on public
benchmark datasets with imbalanced classes and missing values as well as real
data in health applications, and show that our multilevel SVM-based method
produces fast, and more accurate and robust classification results.Comment: arXiv admin note: substantial text overlap with arXiv:1503.0625
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Multi-class protein fold classification using a new ensemble machine learning approach.
Protein structure classification represents an important process in understanding the associations
between sequence and structure as well as possible functional and evolutionary relationships.
Recent structural genomics initiatives and other high-throughput experiments have populated the
biological databases at a rapid pace. The amount of structural data has made traditional methods
such as manual inspection of the protein structure become impossible. Machine learning has been
widely applied to bioinformatics and has gained a lot of success in this research area. This work
proposes a novel ensemble machine learning method that improves the coverage of the classifiers
under the multi-class imbalanced sample sets by integrating knowledge induced from different base
classifiers, and we illustrate this idea in classifying multi-class SCOP protein fold data. We have
compared our approach with PART and show that our method improves the sensitivity of the
classifier in protein fold classification. Furthermore, we have extended this method to learning over
multiple data types, preserving the independence of their corresponding data sources, and show
that our new approach performs at least as well as the traditional technique over a single joined
data source. These experimental results are encouraging, and can be applied to other bioinformatics
problems similarly characterised by multi-class imbalanced data sets held in multiple data
sources
X-ray Astronomical Point Sources Recognition Using Granular Binary-tree SVM
The study on point sources in astronomical images is of special importance,
since most energetic celestial objects in the Universe exhibit a point-like
appearance. An approach to recognize the point sources (PS) in the X-ray
astronomical images using our newly designed granular binary-tree support
vector machine (GBT-SVM) classifier is proposed. First, all potential point
sources are located by peak detection on the image. The image and spectral
features of these potential point sources are then extracted. Finally, a
classifier to recognize the true point sources is build through the extracted
features. Experiments and applications of our approach on real X-ray
astronomical images are demonstrated. comparisons between our approach and
other SVM-based classifiers are also carried out by evaluating the precision
and recall rates, which prove that our approach is better and achieves a higher
accuracy of around 89%.Comment: Accepted by ICSP201
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