18,111 research outputs found
Early hospital mortality prediction using vital signals
Early hospital mortality prediction is critical as intensivists strive to
make efficient medical decisions about the severely ill patients staying in
intensive care units. As a result, various methods have been developed to
address this problem based on clinical records. However, some of the laboratory
test results are time-consuming and need to be processed. In this paper, we
propose a novel method to predict mortality using features extracted from the
heart signals of patients within the first hour of ICU admission. In order to
predict the risk, quantitative features have been computed based on the heart
rate signals of ICU patients. Each signal is described in terms of 12
statistical and signal-based features. The extracted features are fed into
eight classifiers: decision tree, linear discriminant, logistic regression,
support vector machine (SVM), random forest, boosted trees, Gaussian SVM, and
K-nearest neighborhood (K-NN). To derive insight into the performance of the
proposed method, several experiments have been conducted using the well-known
clinical dataset named Medical Information Mart for Intensive Care III
(MIMIC-III). The experimental results demonstrate the capability of the
proposed method in terms of precision, recall, F1-score, and area under the
receiver operating characteristic curve (AUC). The decision tree classifier
satisfies both accuracy and interpretability better than the other classifiers,
producing an F1-score and AUC equal to 0.91 and 0.93, respectively. It
indicates that heart rate signals can be used for predicting mortality in
patients in the ICU, achieving a comparable performance with existing
predictions that rely on high dimensional features from clinical records which
need to be processed and may contain missing information.Comment: 11 pages, 5 figures, preprint of accepted paper in IEEE&ACM CHASE
2018 and published in Smart Health journa
Uncertainty-Aware Attention for Reliable Interpretation and Prediction
Department of Computer Science and EngineeringAttention mechanism is effective in both focusing the deep learning models on relevant features and
interpreting them. However, attentions may be unreliable since the networks that generate them are
often trained in a weakly-supervised manner. To overcome this limitation, we introduce the notion of
input-dependent uncertainty to the attention mechanism, such that it generates attention for each
feature with varying degrees of noise based on the given input, to learn larger variance on instances it
is uncertain about. We learn this Uncertainty-aware Attention (UA) mechanism using variational
inference, and validate it on various risk prediction tasks from electronic health records on which our
model significantly outperforms existing attention models. The analysis of the learned attentions
shows that our model generates attentions that comply with clinicians' interpretation, and provide
richer interpretation via learned variance. Further evaluation of both the accuracy of the uncertainty
calibration and the prediction performance with "I don't know'' decision show that UA yields networks
with high reliability as well.ope
Magnetic-Visual Sensor Fusion-based Dense 3D Reconstruction and Localization for Endoscopic Capsule Robots
Reliable and real-time 3D reconstruction and localization functionality is a
crucial prerequisite for the navigation of actively controlled capsule
endoscopic robots as an emerging, minimally invasive diagnostic and therapeutic
technology for use in the gastrointestinal (GI) tract. In this study, we
propose a fully dense, non-rigidly deformable, strictly real-time,
intraoperative map fusion approach for actively controlled endoscopic capsule
robot applications which combines magnetic and vision-based localization, with
non-rigid deformations based frame-to-model map fusion. The performance of the
proposed method is demonstrated using four different ex-vivo porcine stomach
models. Across different trajectories of varying speed and complexity, and four
different endoscopic cameras, the root mean square surface reconstruction
errors 1.58 to 2.17 cm.Comment: submitted to IROS 201
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
Mining health knowledge graph for health risk prediction
Nowadays classification models have been widely adopted in healthcare, aiming at supporting practitioners for disease diagnosis and human error reduction. The challenge is utilising effective methods to mine real-world data in the medical domain, as many different models have been proposed with varying results. A large number of researchers focus on the diversity problem of real-time data sets in classification models. Some previous works developed methods comprising of homogeneous graphs for knowledge representation and then knowledge discovery. However, such approaches are weak in discovering different relationships among elements. In this paper, we propose an innovative classification model for knowledge discovery from patientsā personal health repositories. The model discovers medical domain knowledge from the massive data in the National Health and Nutrition Examination Survey (NHANES). The knowledge is conceptualised in a heterogeneous knowledge graph. On the basis of the model, an innovative method is developed to help uncover potential diseases suffered by people and, furthermore, to classify patientsā health risk. The proposed model is evaluated by comparison to a baseline model also built on the NHANES data set in an empirical experiment. The performance of proposed model is promising. The paper makes significant contributions to the advancement of knowledge in data mining with an innovative classification model specifically crafted for domain-based data. In addition, by accessing the patterns of various observations, the research contributes to the work of practitioners by providing a multifaceted understanding of individual and public health
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