A multi-chanel electrical impedance meter based on digital lock-in technology

Abstract The presented multichannel measuring system working on various frequencies is suitable either for electrical impedance spectroscopy or tomography. The authors of this paper have developed the complete measurement system and a graphical user interface platform. The accuracy of impedance amplitude and phase are 1 ppm and 0.01°, respectively. The basic instrument works with 8 channels and can be expanded to 64 channels with the application of multiplexing or multiple parallel connected instruments in the same system

An Integrated Analog Readout for Multi-Frequency Bioimpedance Measurements

Bioimpedance spectroscopy is used in a wide range of biomedical applications. This paper presents an integrated analog readout, which employs synchronous detection to perform galvanostatic multi-channel, multi-frequency bioimpedance measurements. The circuit was fabricated in a 0.35-μm CMOS technology and occupies an area of 1.52 mm2. The effect of random dc offsets is investigated, along with the use of chopping to minimize them. Impedance measurements of a known RC load and skin (using commercially available electrodes) demonstrate the operation of the system over a frequency range up to 1 MHz. The circuit operates from a ±2.5 V power supply and has a power consumption of 3.4-mW per channel

Generation of tunable, high repetition rate optical frequency combs using on-chip silicon modulators

We experimentally demonstrate tunable, highly-stable frequency combs with high repetition-rates using a single, charge injection based silicon PN modulator. In this work, we demonstrate combs in the C-band with over 8 lines in a 20-dB bandwidth. We demonstrate continuous tuning of the center frequency in the C-band and tuning of the repetition-rate from 7.5GHz to 12.5GHz. We also demonstrate through simulations the potential for bandwidth scaling using an optimized silicon PIN modulator. We find that, the time varying free carrier absorption due to carrier injection, an undesirable effect in data modulators, assists here in enhancing flatness in the generated combs.Comment: 10 pages, 7 figure

Screen-printed ultrasonic 2-D matrix array transducers for microparticle manipulation

This paper reports the development of a two-dimensional thick film lead zirconate titanate (PZT) ultrasonic transducer array, operating at frequency approximately 7.5 MHz, to demonstrate the potential of this fabrication technique for microparticle manipulation. All layers of the array are screen-printed then sintered on an alumina substrate without any subsequent patterning processes. The thickness of the thick film PZT is 139 ± 2 μm, the element pitch of the array is 2.3 mm, and the dimension of each individual PZT element is 2 × 2 mm2 with top electrode 1.7 × 1.7 mm2. The measured relative dielectric constant of the PZT is 2250 ± 100 and the dielectric loss is 0.09 ± 0.005 at 10 kHz. Finite element analysis was used to predict the behaviour of the array and to optimise its configuration. Electrical impedance spectroscopy and laser vibrometry were used to characterise the array experimentally. The measured surface motion of a single element is on the order of tens of nanometres with a 10 Vpeak continuous sinusoidal excitation. Particle manipulation experiments have been demonstrated with the array by manipulating Ø10 μm polystyrene microspheres in degassed water. The simplified array fabrication process and the bulk production capability of screen-printing suggest potential for the commercialisation of multilayer planar resonant devices for ultrasonic particle manipulation

Interface Circuits for Microsensor Integrated Systems

ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Recent advances in sensing technologies, especially those for Microsensor Integrated Systems, have led to several new commercial applications. Among these, low voltage and low power circuit architectures have gained growing attention, being suitable for portable long battery life devices. The aim is to improve the performances of actual interface circuits and systems, both in terms of voltage mode and current mode, in order to overcome the potential problems due to technology scaling and different technology integrations. Related problems, especially those concerning parasitics, lead to a severe interface design attention, especially concerning the analog front-end and novel and smart architecture must be explored and tested, both at simulation and prototype level. Moreover, the growing demand for autonomous systems gets even harder the interface design due to the need of energy-aware cost-effective circuit interfaces integrating, where possible, energy harvesting solutions. The objective of this Special Issue is to explore the potential solutions to overcome actual limitations in sensor interface circuits and systems, especially those for low voltage and low power Microsensor Integrated Systems. The present Special Issue aims to present and highlight the advances and the latest novel and emergent results on this topic, showing best practices, implementations and applications. The Guest Editors invite to submit original research contributions dealing with sensor interfacing related to this specific topic. Additionally, application oriented and review papers are encouraged.

High-bandwidth microcoil for fast nuclear spin control

The active manipulation of nuclear spins with radio-frequency (RF) coils is at the heart of nuclear magnetic resonance (NMR) spectroscopy and spin-based quantum devices. Here, we present a microcoil transmitter system designed to generate strong RF pulses over a broad bandwidth, allowing for fast spin rotations on arbitrary nuclear species. Our design incorporates: (i) a planar multilayer geometry that generates a large field of 4.35 mT per unit current, (ii) a 50 Ohm transmission circuit with a broad excitation bandwidth of approximately 20 MHz, and (iii) an optimized thermal management for removal of Joule heating. Using individual 13C nuclear spins in the vicinity of a diamond nitrogen-vacancy (NV) center as a test system, we demonstrate Rabi frequencies exceeding 70 kHz and nuclear pi/2 rotations within 3.4 us. The extrapolated values for 1H spins are about 240 kHz and 1 us, respectively. Beyond enabling fast nuclear spin manipulations, our microcoil system is ideally suited for the incorporation of advanced pulse sequences into micro- and nanoscale NMR detectors operating at low (<1 T) magnetic field.Comment: 8 pages, 5 figures. Submitted to Rev. Sci. Inst

Online condition monitoring of lithium ion batteries by performing impedance spectroscopy using a DC-DC converter

Li-Ion batteries are currently being used extensively in a variety of applications such as portable electronics, electric vehicles and grid storage applications, due to the high demand for high power and high energy density storage batteries. However, the usage of Li-Ion batteries requires extensive condition monitoring to increase overall performance and life expectancy. This research is focused on implementing rapid online condition monitoring techniques, using signal injection via the associated power converter in the battery management system. The technique implemented in this work is known as Electrochemical Impedance Spectroscopy (EIS). EIS is a well-known technique, that has been used to characterize an electrochemical cell’s behaviour and state by monitoring changes in the cell's impedance. This is accomplished by injecting currents at different frequencies into the battery and measuring the voltage response. This technique is conventionally implemented, using standard Frequency Response Analysers (FRA), while the battery is disconnected from the load (offline) due to the long procedural times involved. This has limited the use of EIS to laboratory testing. In recent years, there has been literature regarding incorporating EIS testing into the battery system, which is done in mainly 2 ways, by including a linear amplifier into the system to inject the current perturbations directly, or by using the existing circuitry in the BMS (typically the DC-DC converter) to inject the current perturbations using various control techniques. Although, these strategies have been applied in literature for online systems, they are still riddled with a lengthy EIS measurement time issue. This work seeks to significantly reduce the associated testing time with the use broadband signals to implement Impedance Spectroscopy for online systems via the associated BMS converter. Broandband Impedance Spectroscopy (BIS) is implemented by injecting a signal with multiple frequencies concurrently as this allows for quicker measurement. The main contribution of this work is the real-time implementation of a multi-sine broadband excitation via a bi-directional converter that can be used in a varying system. The results obtained were compared to results from an industry standard FRA and showed to produce Nyquist plots with a reasonable error

Designing of a variable frequency standalone impedance analyzer for in vitro biological applications

Maximum biological samples have some electrical property, which gave us a new dimension in the field of biomedical engineering. Now-a-days measurement of impedance by applying an electrical voltage/current, has a broader application for analyzing different biological samples. Most of the devices used for the measurement of bio-impedance are bulky and much costlier. This approach will help us to design a portable, standalone, multi frequency (10Hz – 10kHz) bio-impedance monitoring device with acceptable accuracy and resolution for in-vitro studies of biological cells and tissue

Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation

Near Infrared Spectroscopy (NIRS) can be employed to monitor noninvasively and continuously local changes in hemodynamics and oxygenation of human tissues. A portable NIRS research-grade acquisition system, dedicated to measurements during muscular exercise, is presented. The instrument is able to control up to eight LED sources and two detectors. A digital correlation technique, implemented on a single-chip RISC microcontroller, performs source-to-detector multiplexing. Such algorithm is highly optimized for computational efficiency and ambient noise rejection. Software-configurable input stages allow for flexibility in instrument setup. As a result of the specific correlation technique employed, the instrument is compact, lightweight and efficient. Clinical tests on oxygen consumption show excellent performance

Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation

Near Infrared Spectroscopy (NIRS) can be employed to monitor noninvasively and continuously local changes in hemodynamics and oxygenation of human tissues. A portable NIRS research-grade acquisition system, dedicated to measurements during muscular exercise, is presented. The instrument is able to control up to eight LED sources and two detectors. A digital correlation technique, implemented on a single-chip RISC microcontroller, performs source-to-detector multiplexing. Such algorithm is highly optimized for computational efficiency and ambient noise rejection. Software-configurable input stages allow for flexibility in instrument setup. As a result of the specific correlation technique employed, the instrument is compact, lightweight and efficient. Clinical tests on oxygen consumption show excellent performance