Trend-based analysis of a population model of the AKAP scaffold protein

We formalise a continuous-time Markov chain with multi-dimensional discrete state space model of the AKAP scaffold protein as a crosstalk mediator between two biochemical signalling pathways. The analysis by temporal properties of the AKAP model requires reasoning about whether the counts of individuals of the same type (species) are increasing or decreasing. For this purpose we propose the concept of stochastic trends based on formulating the probabilities of transitions that increase (resp. decrease) the counts of individuals of the same type, and express these probabilities as formulae such that the state space of the model is not altered. We define a number of stochastic trend formulae (e.g. weakly increasing, strictly increasing, weakly decreasing, etc.) and use them to extend the set of state formulae of Continuous Stochastic Logic. We show how stochastic trends can be implemented in a guarded-command style specification language for transition systems. We illustrate the application of stochastic trends with numerous small examples and then we analyse the AKAP model in order to characterise and show causality and pulsating behaviours in this biochemical system

PV Parameter Identification using Reduced I-V Data

In this paper, possibility and accuracy of using reduced I-V data in PV parameter identification are discussed. Based on the linear identification method proposed in [1], six I-V points are used instead of the whole I-V curve to identify the PV parameters. The maximum power point (MPP) is then estimated using the identified I-V and P-V characteristics. Validation is done by using different sets of six points on the I-V curve. Experiment results show that the accurate curve fitting (with low RMSE and MPE) and good estimation of MPP can be achieved

Simulation support for performance assessment of building components

The determination of performance metrics for novel building components requires that the tests are conducted in the outdoor environment. It is usually difficult to do this when the components are located in a full-scale building because of the difficulty in controlling the experiments. Test cells allow the components to be tested in realistic, but controlled, conditions. High-quality outdoor experiments and identification analysis methods can be used to determine key parameters that quantify performance. This is important for achieving standardised metrics that characterise the building component of interest, whether it is a passive solar component such as a ventilated window, or an active component such as a hybrid photovoltaic module. However, such testing and analysis does not determine how the building component will perform when placed in a real building in a particular location and climate. For this, it is necessary to model the whole building with and without the building component of interest. A procedure has been developed, and applied within several major European projects, that consists of calibrating a simulation model with high-quality data from the outdoor tests and then applying scaling and replication to one or more buildings and locations to determine performance in practice of building components. This paper sets out the methodology that has been developed and applied in these European projects. A case study is included demonstrating its application to the performance evaluation of hybrid photovoltaic modules

Measurement-based modelling and validation of PV systems

This paper presents the analysis and results of modelling of various photovoltaic (PV) systems. Two general models are discussed and presented: an analytical model and an equivalent circuit model, both formulated for main PV technologies currently available on the market. Analytical model does not require any PV system specific input data or parameter, and is formulated as a generic performance model of a considered PV technology. Equivalent circuit model, however, requires specific input data and adjustment of the model parameters, in order to provide an accurate representation of a modelled PV system. The paper provides direct comparison of models based on manufacturer’s specification data and available measurements, as well as the discussion of obtained results

Animated computer graphics models of space and earth sciences data generated via the massively parallel processor

The capability was developed of rapidly producing visual representations of large, complex, multi-dimensional space and earth sciences data sets via the implementation of computer graphics modeling techniques on the Massively Parallel Processor (MPP) by employing techniques recently developed for typically non-scientific applications. Such capabilities can provide a new and valuable tool for the understanding of complex scientific data, and a new application of parallel computing via the MPP. A prototype system with such capabilities was developed and integrated into the National Space Science Data Center's (NSSDC) Pilot Climate Data System (PCDS) data-independent environment for computer graphics data display to provide easy access to users. While developing these capabilities, several problems had to be solved independently of the actual use of the MPP, all of which are outlined

Optimal experimental design for mathematical models of haematopoiesis.

The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells. It is known that feedback regulation is crucial to tightly control this system, but the specific mechanisms by which control is exerted are not completely understood. In this work, we aim to uncover the underlying mechanisms in haematopoiesis by conducting perturbation experiments, where animal subjects are exposed to an external agent in order to observe the system response and evolution. We have developed a novel Bayesian hierarchical framework for optimal design of perturbation experiments and proper analysis of the data collected. We use a deterministic model that accounts for feedback and feedforward regulation on cell division rates and self-renewal probabilities. A significant obstacle is that the experimental data are not longitudinal, rather each data point corresponds to a different animal. We overcome this difficulty by modelling the unobserved cellular levels as latent variables. We then use principles of Bayesian experimental design to optimally distribute time points at which the haematopoietic cells are quantified. We evaluate our approach using synthetic and real experimental data and show that an optimal design can lead to better estimates of model parameters

A radial basis function neural network based approach for the electrical characteristics estimation of a photovoltaic module

The design process of photovoltaic (PV) modules can be greatly enhanced by using advanced and accurate models in order to predict accurately their electrical output behavior. The main aim of this paper is to investigate the application of an advanced neural network based model of a module to improve the accuracy of the predicted output I--V and P--V curves and to keep in account the change of all the parameters at different operating conditions. Radial basis function neural networks (RBFNN) are here utilized to predict the output characteristic of a commercial PV module, by reading only the data of solar irradiation and temperature. A lot of available experimental data were used for the training of the RBFNN, and a backpropagation algorithm was employed. Simulation and experimental validation is reported

Solar array fed synchronous reluctance motor driven water pump : an improved performance under partial shading conditions

An improved performance of a photovoltaic (PV) pumping system employing a synchronous reluctance motor (SynRM) under partial shading conditions is proposed. The system does not include the dc-dc converter that is predominantly being utilized for maximizing the output power of the PV array. In addition, storage batteries are also not contained. A conventional inverter connected directly to the PV array is used to drive the SynRM. Further, a control strategy is proposed to drive the inverter so that the maximum output power of the PV array is achieved while the SynRM is working at the maximum torque per Ampere condition. Consequently, this results in an improved system efficiency and cost. Moreover, two maximum power point tracking (MPPT) techniques are compared under uniform and partial shadow irradiation conditions. The first MPPT algorithm is based on the conventional perturbation and observation (P&O) method and the second one uses a differential evolution (DE) optimization technique. It is found that the DE optimization method leads to a higher PV output power than using the P&O method under the partial shadow condition. Hence, the pump flow rate is much higher. However, under a uniform irradiation level, the PV system provides the available maximum power using both MPPT techniques. The experimental measurements are obtained to validate the theoretical work

Neural nets on the MPP

The Massively Parallel Processor (MPP) is an ideal machine for computer experiments with simulated neural nets as well as more general cellular automata. Experiments using the MPP with a formal model neural network are described. The results on problem mapping and computational efficiency apply equally well to the neural nets of Hopfield, Hinton et al., and Geman and Geman

Modeling and Control for Smart Grid Integration of Solar/Wind Energy Conversion System

Performance optimization, system reliability and operational efficiency are key characteristics of smart grid systems. In this paper a novel model of smart grid-connected PV/WT hybrid system is developed. It comprises photovoltaic array, wind turbine, asynchronous (induction) generator, controller and converters. The model is implemented using MATLAB/SIMULINK software package. Perturb and observe (P&O) algorithm is used for maximizing the generated power based on maximum power point tracker (MPPT) implementation. The dynamic behavior of the proposed model is examined under different operating conditions. Solar irradiance, temperature and wind speed data is gathered from a grid connected, 28.8kW solar power system located in central Manchester. Real-time measured parameters are used as inputs for the developed system. The proposed model and its control strategy offer a proper tool for smart grid performance optimization