Signal generation and storage in FRET-based nanocommunications

The paper is concerned with Forster Resonance Energy Transfer (FRET) considered as a mechanism for communication between nanodevices. Two solved issues are reported in the paper, namely: signal generation and signal storage in FRET-based nanonetworks. First, luciferase molecules as FRET transmitters which are able to generate FRET signals themselves, taking energy from chemical reactions without any external light exposure, are proposed. Second, channelrhodopsins as FRET receivers, as they can convert FRET signals into voltage, are suggested. Further, medical in-body systems where both molecule types might be successfully applied, are discussed. Luciferase-channelrhodopsin communication is modeled and its performance is numerically validated, reporting on its throughput, bit error rate, propagation delay and energy consumption

Internet of Bio Nano Things-based FRET nanocommunications for eHealth

The integration of the Internet of Bio Nano Things (IoBNT) with artificial intelligence (AI) and molecular communications technology is now required to achieve eHealth, specifically in the targeted drug delivery system (TDDS). In this work, we investigate an analytical framework for IoBNT with Forster resonance energy transfer (FRET) nanocommunication to enable intelligent bio nano thing (BNT) machine to accurately deliver therapeutic drug to the diseased cells. The FRET nanocommunication is accomplished by using the well-known pair of fluorescent proteins, EYFP and ECFP. Furthermore, the proposed IoBNT monitors drug transmission by using the quenching process in order to reduce side effects in healthy cells. We investigate the IoBNT framework by driving diffusional rate models in the presence of a quenching process. We evaluate the performance of the proposed framework in terms of the energy transfer efficiency, diffusion-controlled rate and drug loss rate. According to the simulation results, the proposed IoBNT with the intelligent bio nano thing for monitoring the quenching process can significantly achieve high energy transfer efficiency and low drug delivery loss rate, i.e., accurately delivering the desired therapeutic drugs to the diseased cell

A comprehensive survey on hybrid communication in context of molecular communication and terahertz communication for body-centric nanonetworks

With the huge advancement of nanotechnology over the past years, the devices are shrinking into micro-scale, even nano-scale. Additionally, the Internet of nano-things (IoNTs) are generally regarded as the ultimate formation of the current sensor networks and the development of nanonetworks would be of great help to its fulfilment, which would be ubiquitous with numerous applications in all domains of life. However, the communication between the devices in such nanonetworks is still an open problem. Body-centric nanonetworks are believed to play an essential role in the practical application of IoNTs. BCNNs are also considered as domain specific like wireless sensor networks and always deployed on purpose to support a particular application. In these networks, electromagnetic and molecular communications are widely considered as two main promising paradigms and both follow their own development process. In this survey, the recent developments of these two paradigms are first illustrated in the aspects of applications, network structures, modulation techniques, coding techniques and security to then investigate the potential of hybrid communication paradigms. Meanwhile, the enabling technologies have been presented to apprehend the state-of-art with the discussion on the possibility of the hybrid technologies. Additionally, the inter-connectivity of electromagnetic and molecular body-centric nanonetworks is discussed. Afterwards, the related security issues of the proposed networks are discussed. Finally, the challenges and open research directions are presented