Quantile regression in partially linear varying coefficient models

Semiparametric models are often considered for analyzing longitudinal data for a good balance between flexibility and parsimony. In this paper, we study a class of marginal partially linear quantile models with possibly varying coefficients. The functional coefficients are estimated by basis function approximations. The estimation procedure is easy to implement, and it requires no specification of the error distributions. The asymptotic properties of the proposed estimators are established for the varying coefficients as well as for the constant coefficients. We develop rank score tests for hypotheses on the coefficients, including the hypotheses on the constancy of a subset of the varying coefficients. Hypothesis testing of this type is theoretically challenging, as the dimensions of the parameter spaces under both the null and the alternative hypotheses are growing with the sample size. We assess the finite sample performance of the proposed method by Monte Carlo simulation studies, and demonstrate its value by the analysis of an AIDS data set, where the modeling of quantiles provides more comprehensive information than the usual least squares approach.Comment: Published in at http://dx.doi.org/10.1214/09-AOS695 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Partially linear additive quantile regression in ultra-high dimension

We consider a flexible semiparametric quantile regression model for analyzing high dimensional heterogeneous data. This model has several appealing features: (1) By considering different conditional quantiles, we may obtain a more complete picture of the conditional distribution of a response variable given high dimensional covariates. (2) The sparsity level is allowed to be different at different quantile levels. (3) The partially linear additive structure accommodates nonlinearity and circumvents the curse of dimensionality. (4) It is naturally robust to heavy-tailed distributions. In this paper, we approximate the nonlinear components using B-spline basis functions. We first study estimation under this model when the nonzero components are known in advance and the number of covariates in the linear part diverges. We then investigate a nonconvex penalized estimator for simultaneous variable selection and estimation. We derive its oracle property for a general class of nonconvex penalty functions in the presence of ultra-high dimensional covariates under relaxed conditions. To tackle the challenges of nonsmooth loss function, nonconvex penalty function and the presence of nonlinear components, we combine a recently developed convex-differencing method with modern empirical process techniques. Monte Carlo simulations and an application to a microarray study demonstrate the effectiveness of the proposed method. We also discuss how the method for a single quantile of interest can be extended to simultaneous variable selection and estimation at multiple quantiles.Comment: Published at http://dx.doi.org/10.1214/15-AOS1367 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Disease Mapping via Negative Binomial Regression M-quantiles

We introduce a semi-parametric approach to ecological regression for disease mapping, based on modelling the regression M-quantiles of a Negative Binomial variable. The proposed method is robust to outliers in the model covariates, including those due to measurement error, and can account for both spatial heterogeneity and spatial clustering. A simulation experiment based on the well-known Scottish lip cancer data set is used to compare the M-quantile modelling approach and a random effects modelling approach for disease mapping. This suggests that the M-quantile approach leads to predicted relative risks with smaller root mean square error than standard disease mapping methods. The paper concludes with an illustrative application of the M-quantile approach, mapping low birth weight incidence data for English Local Authority Districts for the years 2005-2010.Comment: 23 pages, 7 figure