944 research outputs found

    Reducing the primate pet trade: Actions for primatologists

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    This commentary emerged from a panel presentation at the International Primatological Society Congress in Nairobi, Kenya, 2018. The goal was to provide regional updates on the status of primate removal from habitat countries, especially for the pet trade, and develop guidelines that could help primatologists address this critical problem. The trade in live primates includes those used as pets, in entertainment, and as subjects of biomedical experimentation, but here we focus on those primates destined for the pet trade. Such transactions are a hugely lucrative business, impacting hundreds of thousands of individuals annually and affecting the survival of wild populations. Being intimately familiar with primate social behavior, life history and biology, primatologists, whether they work with captive or wild primates, are in a unique position to understand the nature of the trade and attempt to counter its effects. In addition to updating the status of the primate pet trade, we provide recommendations that may help primatologists formulate a plan to deal, locally and regionally, with illegal trafficking in live primates. General guidelines include increasing awareness of local customs, policies and laws; developing collaborative research opportunities for local people; engaging in training/informational opportunities; and instructing on how to take action when encountering illegally‐trafficked primates

    A good patient? How notions of ‘a good patient’ affect patient-nurse relationships and ART adherence in Zimbabwe

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    Background: While patient-provider interactions are commonly understood as mutually constructed relationships, the role of patient behaviour, participation in interactions, and characteristics, particularly ideals surrounding notions of ‘good’ and ‘bad’ patients, are under-examined. This article examines social representations of ‘a good patient’ and how these representations affect patient-healthcare provider relationships and antiretroviral treatment (ART) for people living with HIV. Methods: Using thematic network analysis, we examined interview and focus group transcripts involving 25 healthcare staff, 48 ART users, and 31 carers of HIV positive children, as well as field notes from over 100 hours of ethnographic observation at health centres in rural Zimbabwe. Results: Characteristics of a good patient include obedience, patience, politeness, listening, enthusiasm for treatment, intelligence, physical cleanliness, honesty, gratitude and lifestyle adaptations (taking pills correctly and coming to the clinic when told). Many patients seek to perform within the confines of the ‘good patient persona’ to access good care and ensure continued access to ART; in this way, the notion of a ‘good ART patient’ can have positive effects on patient health outcomes. However, for people not conforming to the norms of the ‘good patient persona’, the productive and health-enabling patient-nurse relationship may break down and be detrimental to the patient. Conclusion: We conclude that policy makers need to take heed of the social representations that govern patient-nurse relationships and their role in facilitating or undermining ART adherence

    Intellectual Property and Alternatives: Strategies for Green Innovation

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    This report provides an analysis of how intellectual property rights (IPRs), and alternatives to IPRs, might operate in green innovation. Part I of the paper discusses the economics of green innovation, including the important role that will need to be played by the private sector. Part II discusses the IPR issues, principally involving patents, that may arise if and when GHG externalities are addressed through the appropriate pricing of greenhouse gases. Part III addresses alternatives to traditional patents and exclusive licenses, including patent pools, liability rules, and prizes

    Ban on Commercial Motorcycle Operations in Benin City, Nigeria: An Appraisal of the Benefits and Business Opportunities

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    This paper appraises the socio-economic implications of the ban on commercial motorcycle operations (CMOs) in Benin City, Nigeria. Deriving from the literature review, the paper posits that although CMOs offered a number of benefits to the users, but that they also had negative effects which include the increase in criminal activities such as armed robbery and kidnapping, and phenomenal rise in the number of motor traffic accidents, many of them fatal. Besides, there were strong indications that insurgents were planning to breach the security of the State by leveraging on the activities of CMOs. Therefore to checkmate the security threat and guarantee the safety and security of the populace, the state government banned CMOs in Benin City. The ban subjected many commuters to immense hardship but it has some benefits and it also created potential business opportunities which the paper identifies. Keywords: Ban, Benefits, Business opportunities, Commercial motorcycles, Insurgents, Operations, Security threat

    A Christian View of Genetic Engineering

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    There has been an age long conflict between religion and science Thus many scientific breakthroughs have literally faulted some religious claims In spite o f this the symbiotic relationship between the duo cannot be overlooked In o ther words there is a recurring scholarly intercourse and intellectual romance between science and religion as established by scholars This paper examines genetic engineer ing from a Chr istian perspective with emphasis on the prospect and burden of the innovation It is premised on Barbour s model for the study of the interaction between Religion and Science and Artigas Complementary Theory which emphasizes the harmonizing and dialoguing roles between science and religion Using content analysis this work delineates the blessing and woes of genetic engineer ing in the Christian context Christianity for instance balances respect for human life and dignity of the human person on the one hand and the blessings of science in human development on the other hand Whereas Christianity appreciates the fact of human creativity in genetic engineer ing as it leads to improved plant and animal lives increased food production and therapeutic functions it equally considers broad implications of this breakthrough on the human person future and his environment It is recommended that man must not lose his dignity nor should genetic engineers arrogate to themselves the Creator s right that is to determine what kind of human that should live or die Moreover religion as part of her oversight and prophetic function must be more proactive than reactive to current scientific progress in genetic engineering in order to guide and guard science from falling into the mash of conceited and self-destructive breakthrough

    Guilt By Genetic Association: The Fourth Amendment and the Search of Private Genetic Databases by Law Enforcement

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    Over the course of 2018, a number of suspects in unsolved crimes have been identified through the use of GEDMatch, a public online genetic database. Law enforcement’s use of GEDMatch to identify suspects in cold cases likely does not constitute a search under the Fourth Amendment because the genetic information hosted on the website is publicly available. Transparency reports from direct-to-consumer (DTC) genetic testing providers like 23andMe and Ancestry suggest that federal and state officials may now be requesting access to private genetic databases as well. Whether law enforcement’s use of private DTC genetic databases to search for familial relatives of a suspect’s genetic profile constitutes a search within the meaning of the Fourth Amendment is far less clear. A strict application of the third-party doctrine suggests that individuals have no expectation of privacy in genetic information that they voluntarily disclose to third parties, including DTC providers. This Note, however, contends that the U.S. Supreme Court’s recent decision in Carpenter v. United States overwhelmingly supports the proposition that genetic information disclosed to third-party DTC providers is subject to Fourth Amendment protection. Approximately fifteen million individuals in the United States have already submitted their genetic information to DTC providers. The genetic information held by these providers can reveal a host of highly intimate details about consumers’ medical conditions, behavioral traits, genetic health risks, ethnic background, and familial relationships. Allowing law enforcement warrantless access to investigate third-party DTC genetic databases circumvents their consumers’ reasonable expectations of privacy by exposing this sensitive genetic information to law enforcement without any meaningful oversight. Furthermore, individuals likely reasonably expect that they retain ownership over their uniquely personal genetic information despite their disclosure of that information to a thirdparty provider. This Note therefore asserts that the third-party doctrine does not permit law enforcement to conduct warrantless searches for suspects on private DTC genetics databases under the Fourth Amendment

    Just two Sides of the Same Coin? Ethical Issues and Discourses on COVID-19 and Ebola: A Comparative Literature Analysis

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    Infectious diseases pose a continuing threat to human life. In the case of pandemics, they can also grow into massive challenges for society as a whole - not only from a medical but also from an ethical perspective. This article takes the current COVID-19 pandemic as the occasion for an empirical medico-ethical analysis. It explores the ethical dimensions and discourses on COVID-19 and the Ebola epidemics (West Africa, Democratic Republic of Congo). Additional attention is paid to the question whether and to what extent the ethical issues raised differ and how the possible disparities can be explained. Using a methodological two-step approach (systematic literature review; qualitative content analysis), we were able to identify nine categories that map the ethical dimensions of recent outbreaks of these two diseases: (1) Prioritization of health, (2) Equitable access to resources, (3) Adequate information, (4) Health worker vulnerability, (5) Stigma and discrimination, (6) Research ethics, (7) Measures restricting freedom, (8) Global health justice, (9) Environmental ethics

    Problems in the control of nematode parasites of small ruminants in Malaysia

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    Nematode parasitic disease, attributed mainly Haemonchus contortus, is the greatest disease problem of small ruminants in Malaysia. This thesis comprises 6 studies on the emergence of anthelmintic resistance in these parasites, and how control may be managed by exploiting the nematophagous fungus Duddingtonia flagrans. A survey of the prevalence of anthelmintic resistance (AR) on Peninsular Malaysia revealed 50% of the sheep (n=39) and 75 % of the goat farms (n=9) were infected with nematode parasites that were resistant to the benzimidazoles. Resistance to levamisole, closantel and ivermectin was also detected. Another study on a government sheep breeding farm, showed multiple AR involving the benzimidazoles, levamisole and ivermectin (plus suspect moxidectin resistance). Continuing these investigations to eastern Malaysia, showed anthelmintic failure to all the broad-spectrum groups on all the government small ruminant breeding farms. New approaches to worm control were urgently required. Studies on the potential of biological control by the use of nematophagous fungi against the free-living stages on pasture, were carried out to assess its suitability and efficacy for use in the tropical environment that is typical for Malaysia. In a survey for the presence of nematode trapping fungi from faecal samples of livestock, several nematophagous species including D. flagrans and Arthrobotrys oligospora were identified. Mass production of D. flagrans spores on various local media was attempted, and the product was also tested in pen trials where sheep were fed the spores at different dose rates, either as a supplement, or in feed blocks. Daily fungal feeding by both means resulted in an 80-95% reduction in infective larvae in faecal cultures. Similar results were found in small scale grazing experiments, where sheep were fed daily with fungal spores for 3 consecutive months. Pen trials comparing goats and sheep, showed no difference between the two livestock species. Larger scale field trials where D. flagrans was combined with rapid rotational grazing, showed excellent parasite control. This indicates that the integration of biological control with measures such as rotational grazing provides viable options for sustainable production of small ruminants in the tropics, where AR is becoming a major threat to livestock production

    Work-Related Violence Research Project: Overview and Survey Module and Focus Group Findings

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    [Excerpt] The main goal of the contract was to provide ILAB with a newly developed set of high quality research tools (i.e., new survey questions module and related focus group protocols) and corresponding methodological recommendations to meet ILAB’s needs for collecting nationally representative, gender-disaggregated data on the prevalence, nature, and possible consequences of adult (18 years of age and older) WRV, including gender-based violence (or GBV) to the extent practicable. ILAB is particularly interested in the formal and informal sectors of one or more of the following Spanish-speaking Central American countries: Panama, Honduras, Nicaragua, El Salvador, Guatemala, and Costa Rica

    Nano-drug Clinical Trials: Informed Consent and Risk Management Through Blockchain

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    Drug bearing nano-shells that can be utilized for targeted drug delivery have been shown to enhance the therapeutic index by increasing the dug concentration in diseased tissue and reducing the toxicity in normal tissue.  The controllability of the drug bearing shell size provides predictability measure for the amount of drug payload per shell which improves the administration of the therapeutic dose.  The FDA approved different formulations for clinical use in metastatic and recurrent breast cancer, among other diseases.  At the moment, some of these formulations are the subject of international clinical trials.  Informed consent is legally mandated in administering drug bearing nano-shells.  The risks of the new formulations, as with all new technologies, are not well known and are continue to be a subject of intensive research, thus exacerbating the existing informed consent legal issues, thus exacerbating the existing informed consent legal issues.  This short essay focuses on proposing a framework to mitigate liabilities administering a new formulation on nano-enabled drug carriers particularly when uncertainties of the benefits and damages are not fully known.
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