Hacia el modelado 3d de tumores cerebrales mediante endoneurosonografía y redes neuronales

Las cirugías mínimamente invasivas se han vuelto populares debido a que implican menos riesgos con respecto a las intervenciones tradicionales. En neurocirugía, las tendencias recientes sugieren el uso conjunto de la endoscopia y el ultrasonido, técnica llamada endoneurosonografía (ENS), para la virtualización 3D de las estructuras del cerebro en tiempo real. La información ENS se puede utilizar para generar modelos 3D de los tumores del cerebro durante la cirugía. En este trabajo, presentamos una metodología para el modelado 3D de tumores cerebrales con ENS y redes neuronales. Específicamente, se estudió el uso de mapas auto-organizados (SOM) y de redes neuronales tipo gas (NGN). En comparación con otras técnicas, el modelado 3D usando redes neuronales ofrece ventajas debido a que la morfología del tumor se codifica directamente sobre los pesos sinápticos de la red, no requiere ningún conocimiento a priori y la representación puede ser desarrollada en dos etapas: entrenamiento fuera de línea y adaptación en línea. Se realizan pruebas experimentales con maniquíes médicos de tumores cerebrales. Al final del documento, se presentan los resultados del modelado 3D a partir de una base de datos ENS.Minimally invasive surgeries have become popular because they reduce the typical risks of traditional interventions. In neurosurgery, recent trends suggest the combined use of endoscopy and ultrasound (endoneurosonography or ENS) for 3D virtualization of brain structures in real time. The ENS information can be used to generate 3D models of brain tumors during a surgery. This paper introduces a methodology for 3D modeling of brain tumors using ENS and unsupervised neural networks. The use of self-organizing maps (SOM) and neural gas networks (NGN) is particularly studied. Compared to other techniques, 3D modeling using neural networks offers advantages, since tumor morphology is directly encoded in synaptic weights of the network, no a priori knowledge is required, and the representation can be developed in two stages: off-line training and on-line adaptation. Experimental tests were performed using virtualized phantom brain tumors. At the end of the paper, the results of 3D modeling from an ENS database are presented

Long-lived protoplanetary disks in multiple systems: the VLA view of HD 98800

The conditions and evolution of protoplanetary disks in multiple systems can be considerably different from those around single stars, which may have important consequences for planet formation. We present Very Large Array (VLA) 8.8 mm (34 GHz) and 5 cm (6 GHz) observations of the quadruple system HD 98800, which consists of two spectroscopic binary systems (Aa-Ab, Ba-Bb). The Ba-Bb pair is surrounded by a circumbinary disk, usually assumed to be a debris disk given its $\sim$10 Myr age and lack of near infrared excess. The VLA 8.8 mm observations resolve the disk size (5-5.5 au) and its inner cavity ($\approx$3 au) for the first time, making it one of the smallest disks known. Its small size, large fractional luminosity, and millimeter spectral index consistent with blackbody emission support the idea that HD 98800 B is a massive, optically thick ring which may still retain significant amounts of gas. The disk detection at 5 cm is compatible with free-free emission from photoionized material. The diskless HD 98800 A component is also detected, showing partial polarization at 5 cm compatible with non-thermal chromospheric activity. We propose that tidal torques from Ba-Bb and A-B have stopped the viscous evolution of the inner and outer disk radii, and the disk is evolving via mass loss through photoevaporative winds. This scenario can explain the properties and longevity of HD 98800 B as well as the lack of a disk around HD 98800 A, suggesting that planet formation could have more time to proceed in multiple systems than around single stars in certain system configurations.Comment: 14 pages, 4 figures, 3 tables; Submitted to ApJ May 14 2018; Accepted to ApJ August 3 2018. This version fixes a mistake in the reported position angle. The order of the figures has been changed to match that of the references in the tex

Spatially resolved CO SLED of the Luminous Merger Remnant NGC 1614 with ALMA

We present high-resolution (1".0) Atacama Large Millimeter/submillimeter Array (ALMA) observations of CO (1-0) and CO (2- 1) rotational transitions toward the nearby IR-luminous merger NGC 1614 supplemented with ALMA archival data of CO (3-2), and CO (6-5) transitions. The CO (6-5) emission arises from the starburst ring (central 590 pc in radius), while the lower-$J$ CO lines are distributed over the outer disk ($\sim$ 3.3 kpc in radius). Radiative transfer and photon dominated region (PDR) modeling reveal that the starburst ring has a single warmer gas component with more intense far-ultraviolet radiation field ($n_{\rm{H_2}}$ $\sim$ 10$^{4.6}$ cm$^{-3}$, $T_{\rm{kin}}$ $\sim$ 42 K, and $G_{\rm{0}}$ $\sim$ 10$^{2.7}$) relative to the outer disk ($n_{\rm{H_2}}$ $\sim$ 10$^{5.1}$ cm$^{-3}$, $T_{\rm{kin}}$ $\sim$ 22 K, and $G_{\rm{0}}$ $\sim$ 10$^{0.9}$). A two-phase molecular interstellar medium with a warm and cold ($>$ 70 K and $\sim$ 19 K) component is also an applicable model for the starburst ring. A possible source for heating the warm gas component is mechanical heating due to stellar feedback rather than PDR. Furthermore, we find evidence for non-circular motions along the north-south optical bar in the lower-$J$ CO images, suggesting a cold gas inflow. We suggest that star formation in the starburst ring is sustained by the bar-driven cold gas inflow, and starburst activities radiatively and mechanically power the CO excitation. The absence of a bright active galactic nucleus can be explained by a scenario that cold gas accumulating on the starburst ring is exhausted as the fuel for star formation, or is launched as an outflow before being able to feed to the nucleus.Comment: 20 pages, 19 figures, 2 tables, accepted for publication in Ap

A radial mass profile analysis of the lensing cluster MS2137-23

We reanalyze the strong lens modeling of the cluster of galaxies MS2137-23 using a new data set obtained with the ESO VLT. We found the photometric redshifts of the two main arc systems are both at z=1.6. After subtraction of the central cD star light of the HST image we found that only one object lying underneath has the expected properties of the fifth image associated to the tangential arc. We improve the previous lens modelings of the central dark matter distribution of the cluster, using an isothermal model with a core (IS) and the NFW-like model with a cusp. Without the fifth image, the arc properties together with the shear map profile are equally well fit by the and by an IS and a sub-class of generalized-NFW mass profiles having inner slope power index in the range 0.7<alpha<1.2. Adding new constrains provided by the fifth image favors IS profiles that better predict the fifth image properties. A model including cluster galaxy perturbations or the the stellar mass distribution does not change our conclusions but imposes the M/L_I of the cD stellar component is below 10 at a 99% confidence level. Using our new detailed lensing model together with Chandra X-ray data and the cD stellar component we finally discuss intrinsic properties of the gravitational potential. Whereas X-ray and dark matter have a similar shape at various radius, the cD stellar isophotes are twisted by 13 deg. The sub- arc-second azimuthal shift we observe between the radial arc position and the predictions of elliptical models correspond to what is expected from a mass distribution twist. This shift may result from a projection effect of the cD and the cluster halos, thus revealing the triaxiality of the system.Comment: Final version accepted in A&

Multiple spiral patterns in the transitional disk of HD 100546

Protoplanetary disks around young stars harbor many structures related to planetary formation. Of particular interest, spiral patterns were discovered among several of these disks and are expected to be the sign of gravitational instabilities leading to giant planets formation or gravitational perturbations caused by already existing planets. In this context, the star HD100546 presents some specific characteristics with a complex gas and dusty disk including spirals as well as a possible planet in formation. The objective of this study is to analyze high contrast and high angular resolution images of this emblematic system to shed light on critical steps of the planet formation. We retrieved archival images obtained at Gemini in the near IR (Ks band) with the instrument NICI and processed the data using advanced high contrast imaging technique taking advantage of the angular differential imaging. These new images reveal the spiral pattern previously identified with HST with an unprecedented resolution, while the large-scale structure of the disk is mostly erased by the data processing. The single pattern at the southeast in HST images is now resolved into a multi-armed spiral pattern. Using two models of a gravitational perturber orbiting in a gaseous disk we attempted to bring constraints on the characteristics of this perturber assuming each spiral being independent and we derived qualitative conclusions. The non-detection of the northeast spiral pattern observed in HST allows to put a lower limit on the intensity ratio between the two sides of the disk, which if interpreted as forward scattering yields a larger anisotropic scattering than derived in the visible. Also, we found that the spirals are likely spatially resolved with a thickness of about 5-10AU. Finally, we did not detect the candidate forming planet recently discovered in the Lp band, with a mass upper limit of 16-18 MJ.Comment: Accepted for publication in Astronomy and Astrophysics, 10 pages, 8 figure

Weighing simulated galaxy clusters using lensing and X-ray

We aim at investigating potential biases in lensing and X-ray methods to measure the cluster mass profiles. We do so by performing realistic simulations of lensing and X-ray observations that are subsequently analyzed using observational techniques. The resulting mass estimates are compared among them and with the input models. Three clusters obtained from state-of-the-art hydrodynamical simulations, each of which has been projected along three independent lines-of-sight, are used for this analysis. We find that strong lensing models can be trusted over a limited region around the cluster core. Extrapolating the strong lensing mass models to outside the Einstein ring can lead to significant biases in the mass estimates, if the BCG is not modeled properly for example. Weak lensing mass measurements can be largely affected by substructures, depending on the method implemented to convert the shear into a mass estimate. Using non-parametric methods which combine weak and strong lensing data, the projected masses within R200 can be constrained with a precision of ~10%. De-projection of lensing masses increases the scatter around the true masses by more than a factor of two due to cluster triaxiality. X-ray mass measurements have much smaller scatter (about a factor of two smaller than the lensing masses) but they are generally biased low by 5-20%. This bias is ascribable to bulk motions in the gas of our simulated clusters. Using the lensing and the X-ray masses as proxies for the true and the hydrostatic equilibrium masses of the simulated clusters and averaging over the cluster sample we are able to measure the lack of hydrostatic equilibrium in the systems we have investigated.Comment: 27 pages, 21 figures, accepted for publication on A&A. Version with full resolution images can be found at http://pico.bo.astro.it/~massimo/Public/Papers/massComp.pd

Three-Dimensional Structure of the Central Region of NGC7027: A Quest for Trails of High-Velocity Jets

We report on the results of a radio interferometric observation of NGC7027 in the CO J=2-1 and 13CO J=2-1 lines. The results are analyzed with morpho-kinematic models developed from the software tool Shape. Our goal is to reveal the morpho-kinematic properties of the central region of the nebula, and to explore the nature of unseen high-velocity jets that may have created the characteristic structure of the central region consisting of molecular and ionized components. A simple ellipsoidal shell model explains the intensity distribution around the systemic velocity, but the high velocity features deviate from the ellipsoidal model. Through the Shape automatic reconstruction model, we found a possible trail of a jet only in one direction, but no other possible holes were created by the passage of a jet.Comment: 26 pages, 13 figures; accepted for publication in AJ; Full resolution version available at http://web.hku.hk/~junichi/paper