Fidelity protocol for the Action Success Knowledge (ASK) trial: A psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia

Introduction: Treatment fidelity is a complex, multifaceted evaluative process which refers to whether a studied intervention was delivered as intended. Monitoring and enhancing fidelity is one recommendation of the TiDIER (Template for Intervention Description and Replication) checklist, as fidelity can inform interpretation and conclusions drawn about treatment effects. Despite the methodological and translational benefits, fidelity strategies have been used inconsistently within health behaviour intervention studies; in particular, within aphasia intervention studies, reporting of fidelity remains relatively rare. This paper describes the development of a fidelity protocol for the Action Success Knowledge (ASK) study, a current cluster randomised trial investigating an early mood intervention for people with aphasia (a language disability caused by stroke). Methods and analysis: A novel fidelity protocol and tool was developed to monitor and enhance fidelity within the two arms (experimental treatment and attention control) of the ASK study. The ASK fidelity protocol was developed based on the National Institutes of Health Behaviour Change Consortium fidelity framework. Ethics and dissemination: The study protocol was approved by the Darling Downs Hospital and Health Service Human Research Ethics Committee in Queensland, Australia under the National Mutual Acceptance scheme of multicentre human research projects. Specific ethics approval was obtained for those participating sites who were not under the National Mutual Agreement at the time of application. The monitoring and ongoing conduct of the research project is in line with requirements under the National Mutual Acceptance. On completion of the trial, findings from the fidelity reviews will be disseminated via publications and conference presentations. Trial registration number ACTRN12614000979651

Notes on the use of RTP for shared workspace applications

The Real-time Transport Protocol, RTP, has become the dominant protocol for streaming audio and video in IP-based environments. A number of proposals have been made which attempt to build on this success and apply RTP for shared workspace applications. We discuss the needs of such applications and the features provided by RTP, with an aim to showing why RTP is not appropriate for such uses

Targeted cortical reorganization using optogenetics in non-human primates.

Brain stimulation modulates the excitability of neural circuits and drives neuroplasticity. While the local effects of stimulation have been an active area of investigation, the effects on large-scale networks remain largely unexplored. We studied stimulation-induced changes in network dynamics in two macaques. A large-scale optogenetic interface enabled simultaneous stimulation of excitatory neurons and electrocorticographic recording across primary somatosensory (S1) and motor (M1) cortex (Yazdan-Shahmorad et al., 2016). We tracked two measures of network connectivity, the network response to focal stimulation and the baseline coherence between pairs of electrodes; these were strongly correlated before stimulation. Within minutes, stimulation in S1 or M1 significantly strengthened the gross functional connectivity between these areas. At a finer scale, stimulation led to heterogeneous connectivity changes across the network. These changes reflected the correlations introduced by stimulation-evoked activity, consistent with Hebbian plasticity models. This work extends Hebbian plasticity models to large-scale circuits, with significant implications for stimulation-based neurorehabilitation

The Validation of Speech Corpora

1.2 Intended audience........................

Database of audio records

Diplomka a prakticky castDiplome with partical part

A low-power opportunistic communication protocol for wearable applications

© 2015 IEEE.Recent trends in wearable applications demand flexible architectures being able to monitor people while they move in free-living environments. Current solutions use either store-download-offline processing or simple communication schemes with real-time streaming of sensor data. This limits the applicability of wearable applications to controlled environments (e.g, clinics, homes, or laboratories), because they need to maintain connectivity with the base station throughout the monitoring process. In this paper, we present the design and implementation of an opportunistic communication framework that simplifies the general use of wearable devices in free-living environments. It relies on a low-power data collection protocol that allows the end user to opportunistically, yet seamlessly manage the transmission of sensor data. We validate the feasibility of the framework by demonstrating its use for swimming, where the normal wireless communication is constantly interfered by the environment