Deep Learning of Unified Region, Edge, and Contour Models for Automated Image Segmentation

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have gained traction in the design of automated segmentation pipelines. Although CNN-based models are adept at learning abstract features from raw image data, their performance is dependent on the availability and size of suitable training datasets. Additionally, these models are often unable to capture the details of object boundaries and generalize poorly to unseen classes. In this thesis, we devise novel methodologies that address these issues and establish robust representation learning frameworks for fully-automatic semantic segmentation in medical imaging and mainstream computer vision. In particular, our contributions include (1) state-of-the-art 2D and 3D image segmentation networks for computer vision and medical image analysis, (2) an end-to-end trainable image segmentation framework that unifies CNNs and active contour models with learnable parameters for fast and robust object delineation, (3) a novel approach for disentangling edge and texture processing in segmentation networks, and (4) a novel few-shot learning model in both supervised settings and semi-supervised settings where synergies between latent and image spaces are leveraged to learn to segment images given limited training data.Comment: PhD dissertation, UCLA, 202

Exemplar Learning for Medical Image Segmentation

Medical image annotation typically requires expert knowledge and hence incurs time-consuming and expensive data annotation costs. To reduce this burden, we propose a novel learning scenario, Exemplar Learning (EL), to explore automated learning processes for medical image segmentation from a single annotated image example. This innovative learning task is particularly suitable for medical image segmentation, where all categories of organs can be presented in one single image for annotation all at once. To address this challenging EL task, we propose an Exemplar Learning-based Synthesis Net (ELSNet) framework for medical image segmentation that enables innovative exemplar-based data synthesis, pixel-prototype based contrastive embedding learning, and pseudo-label based exploitation of the unlabeled data. Specifically, ELSNet introduces two new modules for image segmentation: an exemplar-guided synthesis module, which enriches and diversifies the training set by synthesizing annotated samples from the given exemplar, and a pixel-prototype based contrastive embedding module, which enhances the discriminative capacity of the base segmentation model via contrastive self-supervised learning. Moreover, we deploy a two-stage process for segmentation model training, which exploits the unlabeled data with predicted pseudo segmentation labels. To evaluate this new learning framework, we conduct extensive experiments on several organ segmentation datasets and present an in-depth analysis. The empirical results show that the proposed exemplar learning framework produces effective segmentation results