Automated Home Oxygen Delivery for Patients with COPD and Respiratory Failure: A New Approach

Long-term oxygen therapy (LTOT) has become standard care for the treatment of patients with chronic obstructive pulmonary disease (COPD) and other severe hypoxemic lung diseases. The use of new portable O-2 concentrators (POC) in LTOT is being expanded. However, the issue of oxygen titration is not always properly addressed, since POCs rely on proper use by patients. The robustness of algorithms and the limited reliability of current oximetry sensors are hindering the effectiveness of new approaches to closed-loop POCs based on the feedback of blood oxygen saturation. In this study, a novel intelligent portable oxygen concentrator (iPOC) is described. The presented iPOC is capable of adjusting the O-2 flow automatically by real-time classifying the intensity of a patient's physical activity (PA). It was designed with a group of patients with COPD and stable chronic respiratory failure. The technical pilot test showed a weighted accuracy of 91.1% in updating the O-2 flow automatically according to medical prescriptions, and a general improvement in oxygenation compared to conventional POCs. In addition, the usability achieved was high, which indicated a significant degree of user satisfaction. This iPOC may have important benefits, including improved oxygenation, increased compliance with therapy recommendations, and the promotion of PA

Integrated cockpit for A-129

Weight, size, and mission requirements for the A-129 mandated an integrated system approach for the crew/cockpit interface design. Instead of the usual multitude of cockpit controls, indicators, gauges, and lights, the primary crew interface is a single multifunction keyboard and one or more multifunction CRT display units. This cockpit design approach imposed unusual constraints upon the system architecture to overcome the inherent information access limitations of a data input/output window that was restricted by the available space. The conceptual approach and resulting design of the A-129 cockpit with the intent to enhance the development of cockpit standardization are described

Bilingual negotiation via e-mail: an international project

This article examines selective results of an international e-mail project between 24 students studying law with German (in England) and English (in Germany).1 It refers to outcomes as manifested in the students' written reports and oral assessments, but concentrates on samples of bilingual negotiation between partners as expressed in their e-mails. The article focuses on the design of the project and the socio-cultural environment in which it is situated. Taking into account the relevant research in computer-mediated communication, the design of the project follows two primary objectives: the acquisition of (1) language and (2) content as part of a task-based e-mail exchange

Automatic specification of reliability models for fault-tolerant computers

The calculation of reliability measures using Markov models is required for life-critical processor-memory-switch structures that have standby redundancy or that are subject to transient or intermittent faults or repair. The task of specifying these models is tedious and prone to human error because of the large number of states and transitions required in any reasonable system. Therefore, model specification is a major analysis bottleneck, and model verification is a major validation problem. The general unfamiliarity of computer architects with Markov modeling techniques further increases the necessity of automating the model specification. Automation requires a general system description language (SDL). For practicality, this SDL should also provide a high level of abstraction and be easy to learn and use. The first attempt to define and implement an SDL with those characteristics is presented. A program named Automated Reliability Modeling (ARM) was constructed as a research vehicle. The ARM program uses a graphical interface as its SDL, and it outputs a Markov reliability model specification formulated for direct use by programs that generate and evaluate the model

Wronging a Right: Generating Better Errors to Improve Grammatical Error Detection

Grammatical error correction, like other machine learning tasks, greatly benefits from large quantities of high quality training data, which is typically expensive to produce. While writing a program to automatically generate realistic grammatical errors would be difficult, one could learn the distribution of naturallyoccurring errors and attempt to introduce them into other datasets. Initial work on inducing errors in this way using statistical machine translation has shown promise; we investigate cheaply constructing synthetic samples, given a small corpus of human-annotated data, using an off-the-rack attentive sequence-to-sequence model and a straight-forward post-processing procedure. Our approach yields error-filled artificial data that helps a vanilla bi-directional LSTM to outperform the previous state of the art at grammatical error detection, and a previously introduced model to gain further improvements of over 5% $F_{0.5}$ score. When attempting to determine if a given sentence is synthetic, a human annotator at best achieves 39.39 $F_1$ score, indicating that our model generates mostly human-like instances.Comment: Accepted as a short paper at EMNLP 201

Use of TanDEM-X and Sentinel Products to Derive Gully Activity Maps in Kunene Region (Namibia) Based on Automatic Iterative Random Forest Approach

Gullies are landforms with specific patterns of shape, topography, hydrology, vegetation, and soil characteristics. Remote sensing products (TanDEM-X, Sentinel-1, and Sentinel-2) serve as inputs into an iterative algorithm, initialized using a micromapping simulation as training data, to map gullies in the northwestern of Namibia. A Random Forest Classifier examines pixels with similar characteristics in a pool of unlabeled data, and gully objects are detected where high densities of gully pixels are enclosed by an alpha shape. Gully objects are used in subsequent iterations following a mechanism where the algorithm uses the most reliable pixels as gully training samples. The gully class continuously grows until an optimal scenario in terms of accuracy is achieved. Results are benchmarked with manually tagged gullies (initial gully labeled area <0.3% of the total study area) in two different watersheds (408 and 302 km2, respectively) yielding total accuracies of >98%, with 60% in the gully class, Cohen Kappa >0.5, Matthews Correlation Coefficient >0.5, and receiver operating characteristic Area Under the Curve >0.89. Hence, our method outlines gullies keeping low false-positive rates while the classification quality has a good balance for the two classes (gully/no gully). Results show the most significant gully descriptors as the high temporal radar signal coherence (22.4%) and the low temporal variability in Normalized Difference Vegetation Index (21.8%). This research builds on previous studies to face the challenge of identifying and outlining gully-affected areas with a shortage of training data using global datasets, which are then transferable to other large (semi-) arid regions.This research is part of the DEM_HYDR2024 project sup ported by TanDEM-X Science Team, therefore the authors would like to express thanks to the Deutsches Zentrum für Luft und Raumfahrt (DLR) as the donor for the used TanDEM-X datasets. They acknowledge the financial support provided by the Namibia University of Science and Technology (NUST) within the IRPC research funding programme and to ILMI for the sponsorship of field trips to identify suitable study areas. Finally, they would like to express gratitude toward Heidelberg University and the Kurt-Hiehle-Foundation for facilitating the suitable work conditions during this research

Semi-tied Units for Efficient Gating in LSTM and Highway Networks

Gating is a key technique used for integrating information from multiple sources by long short-term memory (LSTM) models and has recently also been applied to other models such as the highway network. Although gating is powerful, it is rather expensive in terms of both computation and storage as each gating unit uses a separate full weight matrix. This issue can be severe since several gates can be used together in e.g. an LSTM cell. This paper proposes a semi-tied unit (STU) approach to solve this efficiency issue, which uses one shared weight matrix to replace those in all the units in the same layer. The approach is termed "semi-tied" since extra parameters are used to separately scale each of the shared output values. These extra scaling factors are associated with the network activation functions and result in the use of parameterised sigmoid, hyperbolic tangent, and rectified linear unit functions. Speech recognition experiments using British English multi-genre broadcast data showed that using STUs can reduce the calculation and storage cost by a factor of three for highway networks and four for LSTMs, while giving similar word error rates to the original models.Comment: To appear in Proc. INTERSPEECH 2018, September 2-6, 2018, Hyderabad, Indi