Image processing methods and architectures in diagnostic pathology.

Grid technology has enabled the clustering and the efficient and secure access to and interaction among a wide variety of geographically distributed resources such as: supercomputers, storage systems, data sources, instruments and special devices and services. Their main applications include large-scale computational and data intensive problems in science and engineering. General grid structures and methodologies for both software and hardware in image analysis for virtual tissue-based diagnosis has been considered in this paper. This methods are focus on the user level middleware. The article describes the distributed programming system developed by the authors for virtual slide analysis in diagnostic pathology. The system supports different image analysis operations commonly done in anatomical pathology and it takes into account secured aspects and specialized infrastructures with high level services designed to meet application requirements. Grids are likely to have a deep impact on health related applications, and therefore they seem to be suitable for tissue-based diagnosis too. The implemented system is a joint application that mixes both Web and Grid Service Architecture around a distributed architecture for image processing. It has shown to be a successful solution to analyze a big and heterogeneous group of histological images under architecture of massively parallel processors using message passing and non-shared memory

The medical science DMZ: a network design pattern for data-intensive medical science

Abstract: Objective We describe a detailed solution for maintaining high-capacity, data-intensive network flows (eg, 10, 40, 100 Gbps+) in a scientific, medical context while still adhering to security and privacy laws and regulations. Materials and Methods High-end networking, packet-filter firewalls, network intrusion-detection systems. Results We describe a “Medical Science DMZ” concept as an option for secure, high-volume transport of large, sensitive datasets between research institutions over national research networks, and give 3 detailed descriptions of implemented Medical Science DMZs. Discussion The exponentially increasing amounts of “omics” data, high-quality imaging, and other rapidly growing clinical datasets have resulted in the rise of biomedical research “Big Data.” The storage, analysis, and network resources required to process these data and integrate them into patient diagnoses and treatments have grown to scales that strain the capabilities of academic health centers. Some data are not generated locally and cannot be sustained locally, and shared data repositories such as those provided by the National Library of Medicine, the National Cancer Institute, and international partners such as the European Bioinformatics Institute are rapidly growing. The ability to store and compute using these data must therefore be addressed by a combination of local, national, and industry resources that exchange large datasets. Maintaining data-intensive flows that comply with the Health Insurance Portability and Accountability Act (HIPAA) and other regulations presents a new challenge for biomedical research. We describe a strategy that marries performance and security by borrowing from and redefining the concept of a Science DMZ, a framework that is used in physical sciences and engineering research to manage high-capacity data flows. Conclusion By implementing a Medical Science DMZ architecture, biomedical researchers can leverage the scale provided by high-performance computer and cloud storage facilities and national high-speed research networks while preserving privacy and meeting regulatory requirements

Flexible Yet Secure De-Duplication Service for Enterprise Data on Cloud Storage

The cloud storage services bring forth infinite storage capacity and flexible access capability to store and share large-scale content. The convenience brought forth has attracted both individual and enterprise users to outsource data service to a cloud provider. As the survey shows 56% of the usages of cloud storage applications are for data back up and up to 68% of data backup are user assets. Enterprise tenants would need to protect their data privacy before uploading them to the cloud and expect a reasonable performance while they try to reduce the operation cost in terms of cloud storage, capacity and I/Os matter as well as systems’ performance, bandwidth and data protection. Thus, enterprise tenants demand secure and economic data storage yet flexible access on their cloud data. In this paper, we propose a secure de-duplication solution for enterprise tenants to leverage the benefits of cloud storage while reducing operation cost and protecting privacy. First, the solution uses a proxy to do flexible group access control which supports secure de-duplication within a group; Second, the solution supports scalable clustering of proxies to support large-scale data access; Third, the solution can be integrated with cloud storage seamlessly. We implemented and tested our solution by integrating it with Dropbox. Secure de-duplication in a group is performed at low data transfer latency and small storage overhead as compared to de-duplication on plaintext

State of The Art and Hot Aspects in Cloud Data Storage Security

Along with the evolution of cloud computing and cloud storage towards matu- rity, researchers have analyzed an increasing range of cloud computing security aspects, data security being an important topic in this area. In this paper, we examine the state of the art in cloud storage security through an overview of selected peer reviewed publications. We address the question of defining cloud storage security and its different aspects, as well as enumerate the main vec- tors of attack on cloud storage. The reviewed papers present techniques for key management and controlled disclosure of encrypted data in cloud storage, while novel ideas regarding secure operations on encrypted data and methods for pro- tection of data in fully virtualized environments provide a glimpse of the toolbox available for securing cloud storage. Finally, new challenges such as emergent government regulation call for solutions to problems that did not receive enough attention in earlier stages of cloud computing, such as for example geographical location of data. The methods presented in the papers selected for this review represent only a small fraction of the wide research effort within cloud storage security. Nevertheless, they serve as an indication of the diversity of problems that are being addressed

Transforming Energy Networks via Peer to Peer Energy Trading: Potential of Game Theoretic Approaches

Peer-to-peer (P2P) energy trading has emerged as a next-generation energy management mechanism for the smart grid that enables each prosumer of the network to participate in energy trading with one another and the grid. This poses a significant challenge in terms of modeling the decision-making process of each participant with conflicting interest and motivating prosumers to participate in energy trading and to cooperate, if necessary, for achieving different energy management goals. Therefore, such decision-making process needs to be built on solid mathematical and signal processing tools that can ensure an efficient operation of the smart grid. This paper provides an overview of the use of game theoretic approaches for P2P energy trading as a feasible and effective means of energy management. As such, we discuss various games and auction theoretic approaches by following a systematic classification to provide information on the importance of game theory for smart energy research. Then, the paper focuses on the P2P energy trading describing its key features and giving an introduction to an existing P2P testbed. Further, the paper zooms into the detail of some specific game and auction theoretic models that have recently been used in P2P energy trading and discusses some important finding of these schemes.Comment: 38 pages, single column, double spac

Security and Privacy Issues in Cloud Computing

Cloud computing transforming the way of information technology (IT) for consuming and managing, promising improving cost efficiencies, accelerate innovations, faster time-to-market and the ability to scale applications on demand (Leighton, 2009). According to Gartner, while the hype grew ex-ponentially during 2008 and continued since, it is clear that there is a major shift towards the cloud computing model and that the benefits may be substantial (Gartner Hype-Cycle, 2012). However, as the shape of the cloud computing is emerging and developing rapidly both conceptually and in reality, the legal/contractual, economic, service quality, interoperability, security and privacy issues still pose significant challenges. In this chapter, we describe various service and deployment models of cloud computing and identify major challenges. In particular, we discuss three critical challenges: regulatory, security and privacy issues in cloud computing. Some solutions to mitigate these challenges are also proposed along with a brief presentation on the future trends in cloud computing deployment