e-SAFE: Secure, Efficient and Forensics-Enabled Access to Implantable Medical Devices

To facilitate monitoring and management, modern Implantable Medical Devices (IMDs) are often equipped with wireless capabilities, which raise the risk of malicious access to IMDs. Although schemes are proposed to secure the IMD access, some issues are still open. First, pre-sharing a long-term key between a patient's IMD and a doctor's programmer is vulnerable since once the doctor's programmer is compromised, all of her patients suffer; establishing a temporary key by leveraging proximity gets rid of pre-shared keys, but as the approach lacks real authentication, it can be exploited by nearby adversaries or through man-in-the-middle attacks. Second, while prolonging the lifetime of IMDs is one of the most important design goals, few schemes explore to lower the communication and computation overhead all at once. Finally, how to safely record the commands issued by doctors for the purpose of forensics, which can be the last measure to protect the patients' rights, is commonly omitted in the existing literature. Motivated by these important yet open problems, we propose an innovative scheme e-SAFE, which significantly improves security and safety, reduces the communication overhead and enables IMD-access forensics. We present a novel lightweight compressive sensing based encryption algorithm to encrypt and compress the IMD data simultaneously, reducing the data transmission overhead by over 50% while ensuring high data confidentiality and usability. Furthermore, we provide a suite of protocols regarding device pairing, dual-factor authentication, and accountability-enabled access. The security analysis and performance evaluation show the validity and efficiency of the proposed scheme

H2B: Heartbeat-based Secret Key Generation Using Piezo Vibration Sensors

We present Heartbeats-2-Bits (H2B), which is a system for securely pairing wearable devices by generating a shared secret key from the skin vibrations caused by heartbeat. This work is motivated by potential power saving opportunity arising from the fact that heartbeat intervals can be detected energy-efficiently using inexpensive and power-efficient piezo sensors, which obviates the need to employ complex heartbeat monitors such as Electrocardiogram or Photoplethysmogram. Indeed, our experiments show that piezo sensors can measure heartbeat intervals on many different body locations including chest, wrist, waist, neck and ankle. Unfortunately, we also discover that the heartbeat interval signal captured by piezo vibration sensors has low Signal-to-Noise Ratio (SNR) because they are not designed as precision heartbeat monitors, which becomes the key challenge for H2B. To overcome this problem, we first apply a quantile function-based quantization method to fully extract the useful entropy from the noisy piezo measurements. We then propose a novel Compressive Sensing-based reconciliation method to correct the high bit mismatch rates between the two independently generated keys caused by low SNR. We prototype H2B using off-the-shelf piezo sensors and evaluate its performance on a dataset collected from different body positions of 23 participants. Our results show that H2B has an overwhelming pairing success rate of 95.6%. We also analyze and demonstrate H2B's robustness against three types of attacks. Finally, our power measurements show that H2B is very power-efficient

Algorithms design for improving homecare using Electrocardiogram (ECG) signals and Internet of Things (IoT)

Due to the fast growing of population, a lot of hospitals get crowded from the huge amount of patients visits. Moreover, during COVID-19 a lot of patients prefer staying at home to minimize the spread of the virus. The need for providing care to patients at home is essential. Internet of Things (IoT) is widely known and used by different fields. IoT based homecare will help in reducing the burden upon hospitals. IoT with homecare bring up several benefits such as minimizing human exertions, economical savings and improved efficiency and effectiveness. One of the important requirement on homecare system is the accuracy because those systems are dealing with human health which is sensitive and need high amount of accuracy. Moreover, those systems deal with huge amount of data due to the continues sensing that need to be processed well to provide fast response regarding the diagnosis with minimum cost requirements. Heart is one of the most important organ in the human body that requires high level of caring. Monitoring heart status can diagnose disease from the early stage and find the best medication plan by health experts. Continues monitoring and diagnosis of heart could exhaust caregivers efforts. Having an IoT heart monitoring model at home is the solution to this problem. Electrocardiogram (ECG) signals are used to track heart condition using waves and peaks. Accurate and efficient IoT ECG monitoring at home can detect heart diseases and save human lives. As a consequence, an IoT ECG homecare monitoring model is designed in this thesis for detecting Cardiac Arrhythmia and diagnosing heart diseases. Two databases of ECG signals are used; one online which is old and limited, and another huge, unique and special from real patients in hospital. The raw ECG signal for each patient is passed through the implemented Low Pass filter and Savitzky Golay filter signal processing techniques to remove the noise and any external interference. The clear signal in this model is passed through feature extraction stage to extract number of features based on some metrics and medical information along with feature extraction algorithm to find peaks and waves. Those features are saved in the local database to apply classification on them. For the diagnosis purpose a classification stage is made using three classification ways; threshold values, machine learning and deep learning to increase the accuracy. Threshold values classification technique worked based on medical values and boarder lines. In case any feature goes above or beyond these ranges, a warning message appeared with expected heart disease. The second type of classification is by using machine learning to minimize the human efforts. A Support Vector Machine (SVM) algorithm is proposed by running the algorithm on the features extracted from both databases. The classification accuracy for online and hospital databases was 91.67% and 94% respectively. Due to the non-linearity of the decision boundary, a third way of classification using deep learning is presented. A full Multilayer Perceptron (MLP) Neural Network is implemented to improve the accuracy and reduce the errors. The number of errors reduced to 0.019 and 0.006 using online and hospital databases. While using hospital database which is huge, there is a need for a technique to reduce the amount of data. Furthermore, a novel adaptive amplitude threshold compression algorithm is proposed. This algorithm is able to make diagnosis of heart disease from the reduced size using compressed ECG signals with high level of accuracy and low cost. The extracted features from compressed and original are similar with only slight differences of 1%, 2% and 3% with no effects on machine learning and deep learning classification accuracy without the need for any reconstructions. The throughput is improved by 43% with reduced storage space of 57% when using data compression. Moreover, to achieve fast response, the amount of data should be reduced further to provide fast data transmission. A compressive sensing based cardiac homecare system is presented. It gives the channel between sender and receiver the ability to carry small amount of data. Experiment results reveal that the proposed models are more accurate in the classification of Cardiac Arrhythmia and in the diagnosis of heart diseases. The proposed models ensure fast diagnosis and minimum cost requirements. Based on the experiments on classification accuracy, number of errors and false alarms, the dictionary of the compressive sensing selected to be 900. As a result, this thesis provided three different scenarios that achieved IoT homecare Cardiac monitoring to assist in further research for designing homecare Cardiac monitoring systems. The experiment results reveal that those scenarios produced better results with high level of accuracy in addition to minimizing data and cost requirements

Cancelable ECG Biometrics using Compressive Sensing-Generalized Likelihood Ratio Test

Electrocardiogram (ECG) has been investigated as promising biometrics, but it cannot be canceled and re-used once compromised just like other biometrics. We propose methods to overcome the issue of irrevocability in ECG biometrics without compromising performance. Our proposed cancelable user authentication uses a generalized likelihood ratio test (GLRT) based on a composite hypothesis testing in compressive sensing (CS) domain We also propose a permutation-based revocation method for CS-based cancelable biometrics so that it becomes resilient to record multiplicity attack. In addition, to compensate for inevitable performance degradation due to cancelable schemes, we also propose two performance improvement methods without undermining cancelable schemes: a self-guided ECG filtering and a T-wave shift model in our CS-GLRT. Finally, our proposed methods were evaluated for various cancelable biometrics criteria with the public ECG-ID data (89 subjects). Our cancelable ECG biometric methods yielded up to 93.0% detection probability at 2.0% false alarm ratio (PD*) and 3.8% equal error rate (EER), which are comparable to or even better than non-cancelable baseline with 93.2% PD* and 4.8% EER for challenging single pulse ECG authentication, respectively. Our proposed methods met all cancelable biometrics criteria theoretically or empirically. Our cancelable secure user template with our novel revocation process is practically non-invertible and robust to record multiplicity attack

Bioelectronic Sensor Nodes for Internet of Bodies

Energy-efficient sensing with Physically-secure communication for bio-sensors on, around and within the Human Body is a major area of research today for development of low-cost healthcare, enabling continuous monitoring and/or secure, perpetual operation. These devices, when used as a network of nodes form the Internet of Bodies (IoB), which poses certain challenges including stringent resource constraints (power/area/computation/memory), simultaneous sensing and communication, and security vulnerabilities as evidenced by the DHS and FDA advisories. One other major challenge is to find an efficient on-body energy harvesting method to support the sensing, communication, and security sub-modules. Due to the limitations in the harvested amount of energy, we require reduction of energy consumed per unit information, making the use of in-sensor analytics/processing imperative. In this paper, we review the challenges and opportunities in low-power sensing, processing and communication, with possible powering modalities for future bio-sensor nodes. Specifically, we analyze, compare and contrast (a) different sensing mechanisms such as voltage/current domain vs time-domain, (b) low-power, secure communication modalities including wireless techniques and human-body communication, and (c) different powering techniques for both wearable devices and implants.Comment: 30 pages, 5 Figures. This is a pre-print version of the article which has been accepted for Publication in Volume 25 of the Annual Review of Biomedical Engineering (2023). Only Personal Use is Permitte

System-on-Chip Solution for Patients Biometric: A Compressive Sensing-Based Approach

IEEE The ever-increasing demand for biometric solutions for the internet of thing (IoT)-based connected health applications is mainly driven by the need to tackle fraud issues, along with the imperative to improve patient privacy, safety and personalized medical assistance. However, the advantages offered by the IoT platforms come with the burden of big data and its associated challenges in terms of computing complexity, bandwidth availability and power consumption. This paper proposes a solution to tackle both privacy issues and big data transmission by incorporating the theory of compressive sensing (CS) and a simple, yet, efficient identification mechanism using the electrocardiogram (ECG) signal as a biometric trait. Moreover, the paper presents the hardware implementation of the proposed solution on a system on chip (SoC) platform with an optimized architecture to further reduce hardware resource usage. First, we investigate the feasibility of compressing the ECG data while maintaining a high identification quality. The obtained results show a 98.88% identification rate using only a compression ratio of 30%. Furthermore, the proposed system has been implemented on a Zynq SoC using heterogeneous software/hardware solution, which is able to accelerate the software implementation by a factor of 7.73 with a power consumption of 2.318 W

Sparse analyzer tool for biomedical signals

IF/00325/2015 PCIF/SSI/0102/2017 UIDB/04111/2020The virtual (software) instrument with a statistical analyzer for testing algorithms for biomedical signals’ recovery in compressive sensing (CS) scenario is presented. Various CS reconstruction algorithms are implemented with the aim to be applicable for different types of biomedical signals and different applications with under-sampled data. Incomplete sampling/sensing can be considered as a sort of signal damage, where missing data can occur as a result of noise or the incomplete signal acquisition procedure. Many approaches for recovering the missing signal parts have been developed, depending on the signal nature. Here, several approaches and their applications are presented for medical signals and images. The possibility to analyze results using different statistical parameters is provided, with the aim to choose the most suitable approach for a specific application. The instrument provides manifold possibilities such as fitting different parameters for the considered signal and testing the efficiency under different percentages of missing data. The reconstruction accuracy is measured by the mean square error (MSE) between original and reconstructed signal. Computational time is important from the aspect of power requirements, thus enabling the selection of a suitable algorithm. The instrument contains its own signal database, but there is also the possibility to load any external data for analysis.publishersversionpublishe

IoT-Based Applications in Healthcare Devices

The last decade has witnessed extensive research in the field of healthcare services and their technological upgradation. To be more specific, the Internet of Things (IoT) has shown potential application in connecting various medical devices, sensors, and healthcare professionals to provide quality medical services in a remote location. This has improved patient safety, reduced healthcare costs, enhanced the accessibility of healthcare services, and increased operational efficiency in the healthcare industry. The current study gives an up-to-date summary of the potential healthcare applications of IoT- (HIoT-) based technologies. Herein, the advancement of the application of the HIoT has been reported from the perspective of enabling technologies, healthcare services, and applications in solving various healthcare issues. Moreover, potential challenges and issues in the HIoT system are also discussed. In sum, the current study provides a comprehensive source of information regarding the different fields of application of HIoT intending to help future researchers, who have the interest to work and make advancements in the field to gain insight into the topic

Bio-signals compression using auto-encoder

Latest developments in wearable devices permits un-damageable and cheapest way for gathering of medical data such as bio-signals like ECG, Respiration, Blood pressure etc. Gathering and analysis of various biomarkers are considered to provide anticipatory healthcare through customized applications for medical purpose. Wearable devices will rely on size, resources and battery capacity; we need a novel algorithm to robustly control memory and the energy of the device. The rapid growth of the technology has led to numerous auto encoders that guarantee the results by extracting feature selection from time and frequency domain in an efficient way. The main aim is to train the hidden layer to reconstruct the data similar to that of input. In the previous works, to accomplish the compression all features were needed but in our proposed framework bio-signals compression using auto-encoder (BCAE) will perform task by taking only important features and compress it. By doing this it can reduce power consumption at the source end and hence increases battery life. The performance of the result comparison is done for the 3 parameters compression ratio, reconstruction error and power consumption. Our proposed work outperforms with respect to the SURF method