28,117 research outputs found

    A Compact High Energy Camera (CHEC) for the Gamma-ray Cherenkov Telescope of the Cherenkov Telescope Array

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    The Gamma-ray Cherenkov Telescope (GCT) is one of the Small Size Telescopes (SSTs) proposed for the Cherenkov Telescope Array (CTA) aimed at the 1 TeV to 300 TeV energy range. GCT will be equipped with a Compact High-Energy Camera (CHEC) containing 2048 pixels of physical size about 6×\times6~mm2^2, leading to a field of view of over 8 degrees. Electronics based on custom TARGET ASICs and FPGAs sample incoming signals at a gigasample per second and provide a flexible triggering scheme. Waveforms for every pixel in every event are read out are on demand without loss at over 600 events per second. A GCT prototype in Meudon, Paris saw first Cherenkov light from air showers in late 2015, using the first CHEC prototype, CHEC-M. This contribution presents results from lab and field tests with CHEC-M and the progress made to a robust camera design for deployment within CTA.Comment: All CTA contributions at arXiv:1709.0348

    Implementation of explosion safety regulations in design of a mobile robot for coal mines

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    The article focuses on specific challenges of the design of a reconnaissance mobile robotic system aimed for inspection in underground coal mine areas after a catastrophic event. Systems that are designated for these conditions must meet specific standards and regulations. In this paper is discussed primarily the main conception of meeting explosion safety regulations of European Union 2014/34/EU (also called ATEX-from French "Appareils destines a etre utilises en ATmospheres Explosives") for Group I (equipment intended for use in underground mines) and Category M1 (equipment designed for operation in the presence of an explosive atmosphere). An example of a practical solution is described on main subsystems of the mobile robot TeleRescuera teleoperated robot with autonomy functions, a sensory subsystem with multiple cameras, three-dimensional (3D) mapping and sensors for measurement of gas concentration, airflow, relative humidity, and temperatures. Explosion safety is ensured according to the Technical Report CLC/TR 60079-33 "s" by two main independent protections-mechanical protection (flameproof enclosure) and electrical protection (automatic methane detector that disconnects power when methane breaches the enclosure and gets inside the robot body).Web of Science811art. no. 230

    Current optical technologies for wireless access

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    The objective of this paper is to describe recent activities and investigations on free-space optics (FSO) or optical wireless and the excellent results achieved within SatNEx an EU-framework 6th programme and IC 0802 a COST action. In a first part, the FSO technology is briefly discussed. In a second part, we mention some performance evaluation criterions for the FSO. In third part, we briefly discuss some optical signal propagation experiments through the atmosphere by mentioning network architectures for FSO and then discuss the recent investigations in airborne and satellite application experiments for FSO. In part four, we mention some recent investigation results on modelling the FSO channel under fog conditions and atmospheric turbulence. Additionally, some recent major performance improvement results obtained by employing hybrid systems and using some specific modulation and coding schemes are presented

    Using stratified medicine to understand, diagnose, and treat neuropathic pain

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    Neuropathic pain (NeuP) is defined as pain arising from a lesion or disease of the somatosensory nervous system. NeuP is common, affecting approximately 6-8% of the general population and currently treatment is inadequate due to both poor drug efficacy and tolerability. Many different types of injury can cause neuropathic pain including genetic (e.g. SCN9A gain of function variants), metabolic (e.g. diabetic polyneuropathy), infective (e.g. HIV associated neuropathy, hepatitis), traumatic and toxic (e.g. chemotherapy induced neuropathy) causes. Such injurious events can impact on anatomically distinct regions of the somatosensory nervous system ranging from the terminals of nociceptive afferents (in small fiber neuropathy) to the thalamus (in post-stroke pain). Classification of neuropathic pain using etiology and location remains an important aspect of routine clinical practice; however, pain medicine is coming to the realization that we need more precision in this classification. The hope is that improved classification will lead to better understanding of risk, prognosis and optimal treatment of NeuP

    Experimentally-calibrated population of models predicts and explains inter-subject variability in cardiac cellular\ud electrophysiology

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    Cellular and ionic causes of variability in the electrophysiological activity of hearts from individuals of the same species are unknown. However, improved understanding of this variability is key to enable prediction of the response of specific hearts to disease and therapies. Limitations of current mathematical modeling and experimental techniques hamper our ability to provide insight into variability. Here we describe a methodology to unravel the ionic determinants of inter-subject variability exhibited in experimental recordings, based on the construction and calibration of populations of models. We illustrate the methodology through its application to rabbit Purkinje preparations, due to their importance in arrhythmias and safety pharmacology assessment. We consider a set of equations describing the biophysical processes underlying rabbit Purkinje electrophysiology and we construct a population of over 10,000 models by randomly assigning specific parameter values corresponding to ionic current conductances and kinetics. We calibrate the model population by closely comparing simulation output and experimental recordings at three pacing frequencies. We show that 213 of the 10,000 candidate models are fully consistent with the experimental dataset. Ionic properties in the 213 models cover a wide range of values, including differences up to ±100% in several conductances. Partial correlation analysis shows that particular combinations of ionic properties determine the precise shape, amplitude and rate dependence of specific action potentials. Finally, we demonstrate that the population of models calibrated using data obtained under physiological conditions quantitatively predicts the action potential duration prolongation caused by exposure to four concentrations of the potassium channel blocker dofetilide

    European Union Acts project MIDAS: objectives and progress to date

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    Introduction to the ACTS program: Advanced Communications and Technology and Services, known simply as ACTS, is one of the specific programmes of the "Fourth Framework Programme of European Community activities in the field of research and technological development and demonstration (1994-1998)". It provides the main focus of the European Unions research effort to accelerate deployment of advanced communications infrastructures and services, and is complemented by extensive European research in the areas of information technology and telematics. The stated objectives of ACTS are to "develop advanced communication systems and services for economic development and social cohesion within Europe, taking account of the rapid evolution of technologies, the changing regulatory situation and opportunities for development of advanced transeuropean networks and services". Within ACTS, the emphasis of the work has shifted from the exploration of fundamental concepts and detailed system engineering, as it had been in earlier programs such as RACE (Research and development in Advanced Communication technologies for Europe), to issues relating to implementation of advanced systems and generic services, and applications which demonstrate the potential use of advanced communications in Europe. A key feature of the ACTS program is that the research be undertaken in the context of real-world trials. Work within the program is divided into six technical areas: Interactive digital multimedia services, photonic technologies, high speed networking, mobility and personal communication networks, intelligence in networks and services and quality, safety and security of communication systems and services. The total EU budget for the ACTS program is approximately 670 MECU, covering around 160 projects, with over 1000 individual organisations participating within the program, thereby illustrating the scale of the activities. MIDAS is one of five projects in the technical area of photonic technologies concerned with high speed transmission, the others being ESTHER, UPGRADE, HIGHWAY and SPEED, each concerned with various aspects or approaches to the development of 40 GBit/s transmission systems within the European arena. A full list of project descriptions and objectives, as well as those of the ACTS program as a whole, are to be found in Ref [1]. The MIDAS consortium consists of the following organisations: Chalmers University of Technology (Sweden), CSELT (Italy), Thomson LCR (France), United Monolithic Semiconductor (France), Telia (Sweden), Kings College London (UK), University of Athens (Greece), ORC University of Southampton (UK). The project started in September 1995 and is currently scheduled to finish in September 1998
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