333 research outputs found

    Teaching White Papers Through Client Projects

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    White papers are increasingly prevalent in business and professional settings. Although textbook resources for white paper assignments are limited, a white paper assignment completed for a community client can provide a learning experience that students enjoy and that strengthens ties between the university and the community. This article describes a way to approach the white paper assignment in a communications-focused course and identifies resources to support white paper assignments

    The Ethics of Plain Language: A Technical Communicator\u27s Perspective

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    I appreciate the opportunity to write to lawyers about the ethics of plain language from a technical-communication perspective. I am a professor of technical communication and, formerly, a full-time technical writer. In this article, I’ll view the ethics of plain language through the lens of the literature on ethics in the field of technical communication

    Writing Toward Readers\u27 Better Health: A Case Study Examining the Development of Online Health Information

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    Each year, more people search the Internet for health information. Through a case study conducted at a prominent health information company, I will show that technical communicators are well suited to contribute to the development of online health information. Like other technical communicators, online health information developers must make rhetorical choices based on audience needs, function within specific social contexts, and work through challenges of writing, editing, and project management

    A father in prison is still a father: paternal imprisonment and infant mental health

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    Recent evidence suggests that school nurses are best placed to raise awareness and support families affected by paternal imprisonment. Less emphasis has been placed on health visitor practice in working with and supporting families with children under the age of five involved in the criminal justice system and yet professionals working in the area offer a potential in addressing the needs of these families. Through presenting findings from a review of the literature undertaken to explore the impact of father imprisonment on infant mental health, this paper seeks to discuss emerging findings from the current evidence-base

    Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors

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    Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells. In order to differentiate between the direct effects of FSH on spermatogenesis and those mediated indirectly through androgen action we have crossed hypogonadal (hpg) mice which lack gonadotrophins with mice lacking androgen receptors (AR) either ubiquitously (ARKO) or specifically on the Sertoli cells (SCARKO). These hpg.ARKO and hpg.SCARKO mice were treated with recombinant FSH for 7 days and testicular morphology and cell numbers assessed. In untreated hpg and hpg.SCARKO mice germ cell development was limited and did not progress beyond the pachytene stage. In hpg.ARKO mice testes were smaller with fewer Sertoli cells and germ cells compared to hpg mice. Treatment with FSH had no effect on Sertoli cell number but significantly increased germ cell numbers in all groups. In hpg mice FSH increased numbers of spermatogonia and spermatocytes and induced round spermatid formation. In hpg.SCARKO and hpg.ARKO mice, in contrast, only spermatogonial and spermatocyte numbers were increased with no formation of spermatids. Leydig cell numbers were increased by FSH in hpg and hpg.SCARKO mice but not in hpg.ARKO mice. Results show that in rodents 1) FSH acts to stimulate spermatogenesis through an increase in spermatogonial number and subsequent entry of these cells into meiosis, 2) FSH has no direct effect on the completion of meiosis and 3) FSH effects on Leydig cell number are mediated through interstitial ARs

    Visual Rhetoric: A Case for Visual Literacy in the Classroom

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    We live in a visual age in which we find visual information surrounding us on every side. The persuasive power of the visual has long been recognized by scholars, but there is a lack of emphasis in the classroom on how to effectively create an effectively persuasive visual. Professors at the collegiate level need to teach their students to be visually literate, to make them responsible users and creators of images

    Redeeming Femininity: A Steinian Catholic Feminist Reading of Flannery O\u27Connor\u27s Short Fiction

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    By situating an analysis of Flannery O’Connor’s short fiction in conversation with Edith Stein’s theology of gender, this project contributes to the critical conversation that interprets O’Connor’s fiction through various feminist frameworks. I respond by proposing an alternative feminist framework that centers O’Connor’s sacramental or incarnational vision of the human body and her characters’ movement from fallenness to redemption. Stein’s theology posits that men and women live their fallenness and redemption in differentiated ways that correspond to their embodied masculinity and femininity, respectively. For men, participating in redemption involves imitating the sacrificial love of Christ’s crucifixion. For women, participating in redemption involves imitating Christ’s mother by paradoxically living out both spiritual maternity and spiritual virginity, which is possible in various states of life and professions. I argue that O’Connor’s short fiction dramatizes and embodies Stein’s theology of gender posited in her Essays on Woman, which I refer to as “Catholic feminism.” To illustrate my argument, I examine eight of O’Connor’s short stories through the lens of Stein’s Catholic feminism. Chapter one argues that O’Connor’s stories “A View of the Woods” (1957), “The Life You Save May Be Your Own” (1953), and “Parker’s Back” (1965) dramatize a movement from fallen masculinity to redeemed masculinity, culminating in the male character’s identification with Christ. Chapter two argues that O’Connor’s stories “Good Country People” (1955), “Greenleaf” (1956), and “A Good Man Is Hard to Find” (1953) dramatize a movement from fallen femininity to redeemed femininity, with a particular focus on the spiritual maternity of their characters. Chapter three argues that O’Connor’s stories “The Crop” (1947), “Good Country People” (1955), and “A Temple of the Holy Ghost” (1955) also dramatize a movement from fallen femininity to redeemed femininity, focusing more particularly on the spiritual virginity and individuality of their characters. I conclude that a Steinian reading of O’Connor’s fiction invites new readings that harmonize her redemptive and incarnational vision with the critical concerns raised by other theoretical lenses

    Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen

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    Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis. In this study we generated mice lacking both FSH receptors (FSHRKO) and androgen receptors on the Sertoli cell (SCARKO) to examine how FSH and androgen combine to regulate Sertoli cell function and spermatogenesis. Sertoli cell number in FSHRKO-SCARKO mice was reduced by about 50% but was not significantly different from FSHRKO mice. In contrast, total germ cell number in FSHRKO-SCARKO mice was reduced to 2% of control mice (and 20% of SCARKO mice) due to a failure to progress beyond early meiosis. Measurement of Sertoli cell-specific transcript levels showed that about a third were independent of hormonal action on the Sertoli cell, whereas others were predominantly androgen dependent or showed redundant control by FSH and androgen. Results show that FSH and androgen act through redundant, additive, and synergistic regulation of spermatogenesis and Sertoli cell activity. In addition, the Sertoli cell retains a significant capacity for activity, which is independent of direct hormonal regulation

    Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice

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    Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis. This review examines the regulation and function of these cell during fetal and post-natal development. Fetal Leydig cells are sensitive to both luteinising hormone (LH) and adrenocorticotrophic hormone (ACTH) but Leydig cell function appears normal in fetal mice lacking both hormones or their receptors. Post-natally, the Sertoli cells and Leydig cells are reliant upon the pituitary gonadotrophins. Leydig cells are critically dependent on LH but follicle-stimulating hormone (FSH), presumably acting through the Sertoli cell, can also affect Leydig cell function. Testosterone secreted by the Leydig cells acts with FSH to stimulate Sertoli cell activity and spermatogenesis. Study of animals lacking FSH-receptors and androgen-receptors shows that both hormones can act to maintain the meiotic germ cell population but that androgens are critical for completion of meiosis
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