Obstacles to Optimal Policy: The Interplay of Politics and Economics in Shaping Bank Supervision and Regulation Reforms

This paper provides a positive political economy analysis of the most important revision of the U.S. supervision and regulation system during the last two decades, the 1991 Federal Deposit Insurance Corporation Improvement Act (FDICIA). We analyze the impact of private interest groups as well as political-institutional factors on the voting patterns on amendments related to FDICIA and its final passage to assess the empirical importance of different types of obstacles to welfare-enhancing reforms. Rivalry of interests within the industry (large versus small banks) and between industries (banks versus insurance) as well as measures of legislator ideology and partisanship play important roles and, hence, should be taken into account in order to implement successful change. A divide and conquer' strategy with respect to the private interests appears to be effective in bringing about legislative reform. The concluding section draws tentative lessons from the political economy approaches about how to increase the likelihood of welfare-enhancing regulatory change.

Preferred roles in treatment decision making among patients with cancer: A pooled analysis of studies using the control preferences scale

OBJECTIVES: To collect normative data, assess differences between demographic groups, and indirectly compare US and Canadian medical systems relative to patient expectations of involvement in cancer treatment decision making. STUDY DESIGN: Meta-analysis. METHODS: Individual patient data were compiled across 6 clinical studies among 3491 patients with cancer who completed the 2-item Control Preferences Scale indicating the roles they preferred versus actually experienced in treatment decision making. RESULTS: The roles in treatment decision making that patients preferred were 26% active, 49% collaborative, and 25% passive. The roles that patients reported actually experiencing were 30% active, 34% collaborative, and 36% passive. Roughly 61% of patients reported having their preferred role; only 6% experienced extreme discordance between their preferred versus actual roles. More men than women (66% vs 60%, P = .001) and more US patients than Canadian patients (84% vs 54%, P <.001) reported concordance between their preferred versus actual roles. More Canadian patients than US patients preferred and actually experienced (42% vs 18%, P <.001) passive roles. More women than men reported taking a passive role (40% vs 24%, P <.001). Older patients preferred and were more likely than younger patients to assume a passive role. CONCLUSIONS: Roughly half of the studied patients with cancer indicated that they preferred to have a collaborative relationship with physicians. Although most patients had the decision-making role they preferred, about 40% experienced discordance. This highlights the need for incorporation of individualized patient communication styles into treatment plans

Continent-wide association of H5N1 outbreaks in wild and domestic birds in Europe

The highly pathogenic avian influenza strain H5N1 was first detected in Europe in 2005, and has since been documented continent-wide in wild birds and poultry. However, the relative roles of each host group in transmission remain contentious. Using recently developed tools for analysis of ecological niches and geographic distributions of species, we compared ecological niche requirements for H5N1 between paired host groups (poultry versus wild birds, Anseriformes versus Falconiformes, swans versus non-swan Anseriformes). If environmental signals of different host groups are significantly different, the groups are likely to be involved in distinct transmission cycles. In contrast, models for which similarity cannot be rejected imply no unique ecological niches and no potential linkage of transmission cycles. In 24 similarity tests, we found significant similarity (13/24) or no significant differences (9/24). Although 2 of the 24 analyses showed significant differences, neither was unequivocal, so we conclude an overall signal of niche similarity among groups. We thus could not document distinct ecological niches for H5N1 occurrences in different host groups and conclude that the transmission cycles are broadly interwoven

Physiological responses to verbally inaccessible pictorial information in the left and right hemispheres. Neuropsychology

We investigated the effects of very brief pictorial information on transfer between the cerebral hemispheres through recordings of skin conductance responses. The pictorial stimuli had been judged previously as "neutral", "positive", or "negative" by an independent group of subjects. The verbally-available stimuli (VA) were neutral whereas the very brief, verbally-unavailable stimuli (VU) were positive or negative. The VA and VU stimuli were presented simultaneously, either in the same visual half-field (intra-hemispheric interference) or in the opposite visual half-field (inter-hemispheric interference). In a third condition, there were only VA stimuli in either visual field (no interference). We found that the right hemisphere was especially sensitive to negative VU presentations, both in the inter-and intra-hemispheric interference groups. The left hemisphere showed a corresponding sensitivity to positive interference, but only in the inter-hemispheric interference group. These findings confirm the hemispheric roles in mediating positive versus negative emotions and they show that in the interplay between hemispheric specialization and commissural transfer, left to right transfer can take place without linguistic cognition

The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation

The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert regulatory and suppressive roles over the immune system. After allogeneic stem cell transplantation, regulatory T cells are known to mitigate graft versus host disease while probably maintaining a graft versus leukemia effect. Short alleles (≤(GT)15) for the (GT)n polymorphism in the promoter/enhancer of FOXP3 are associated with a higher expression of FOXP3, and hypothetically with an increase of regulatory T cell activity. This polymorphism has been related to the development of auto- or alloimmune conditions including type 1 diabetes or graft rejection in renal transplant recipients. However, its impact in the allo-transplant setting has not been analyzed. In the present study, which includes 252 myeloablative HLA-identical allo-transplants, multivariate analysis revealed a lower incidence of grade III-IV acute graft versus host disease (GVHD) in patients transplanted from donors harboring short alleles (OR = 0.26, CI 0.08-0.82, p = 0.021); without affecting chronic GVHD or graft versus leukemia effect, since cumulative incidence of relapse, event free survival and overall survival rates are similar in both groups of patients

Fixed gonadotropin-releasing hormone antagonist protocol versus gonadotropin-releasing hormone agonist long protocol in patients with polycystic ovary syndrome treated for intracytoplasmic sperm injection cycles

Background: Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation syndrome (OHSS) during ovarian stimulation. Use of GnRH antagonist in the general sub fertile population is associated with lower incidence of (OHSS) than agonists and similar probability of live birth but it is unclear. Our Objective was to compare the fixed GnRH antagonist and GnRH agonist long protocols in patients with PCOS undergoing IVF.Methods: In this randomized controlled trial (RCT), 200 patients with PCOS were randomly allocated in two groups: long GnRH (n = 100) and fixed GnRH antagonist protocol (n = 100).           Results: There is significant difference was observed in chemical pregnancy rate (46.0% versus 31.0%), and clinical pregnancy rate (43.0% versus 29.0%) in agonist and antagonist protocols, respectively. Duration of stimulation was significantly higher in agonist group (13.58 versus 12.381 days), respectively.  Total number of ampoules of gonadotrophin is comparable in both groups (t=1.914, p=0.057).Conclusions: The use of GnRH antagonists is more advantageous than GnRH agonists in relation to shorter duration of stimulation thus allowing a reduction in the treatment time that makes COS less costly and better patient compliance. In this study GnRH agonist shows higher pregnancy rate than antagonist, so larger studies needed to clarify their roles

A Means-End Study of Outcome Differences of Females and Males Associated with Outward Bound and National Outdoor Leadership School

This study compares outcomes of male and female participants from Outward Bound (OB) and National Outdoor Leadership Schools (NOLS) courses during the summer of 2006. Means-end theory was used to analyze the differences in males versus females from the 510 subjects\u27 responses. Understanding the differences between the outcomes males and females obtain can lead to specific programming objectives. This can impact how organizations such as OB and NOLS program for both gender-specific and co-educational groups. So therefore, by gaining knowledge of differences between males and females we can then gain an understanding of gender roles and frameworks

Reputation or relationships: What really drives perceptions of employer attractiveness in the health industry?

Managing relationships with key stakeholders has long been regarded as a central concern of corporate public relations. In recent years, however, the concept of reputation management has gained rapidly in popularity, potentially supplanting relationships as the discipline's driving philosophy. This paper presents a case study of a major private hospital in Australia, focusing on the respective roles of corporate reputation versus relationships in forming perceptions of employer attractiveness. Through depth interviews and focus groups involving hospital management and highly skilled professionals, this study investigates what drives perceptions of employer attractiveness. Ramifications for the theory and practice of public relations are discussed

A Means-End Study of Outcome Differences of Females and Males Associated with Outward Bound and National Outdoor Leadership School

This study compares outcomes of male and female participants from Outward Bound (OB) and National Outdoor Leadership Schools (NOLS) courses during the summer of 2006. Means-end theory was used to analyze the differences in males versus females from the 510 subjects\u27 responses. Understanding the differences between the outcomes males and females obtain can lead to specific programming objectives. This can impact how organizations such as OB and NOLS program for both gender-specific and co-educational groups. So therefore, by gaining knowledge of differences between males and females we can then gain an understanding of gender roles and frameworks