Development of an In-Vitro Passive and Active Motion Simulator for the Investigation of Shoulder Function and Kinematics

Injuries and degenerative diseases of the shoulder are common and may relate to the joint’s complex biomechanics, which rely primarily on soft tissues to achieve stability. Despite the prevalence of these disorders, there is little information about their effects on the biomechanics of the shoulder, and a lack of evidence with which to guide clinical practice. Insight into these disorders and their treatments can be gained through in-vitro biomechanical experiments where the achieved physiologic accuracy and repeatability directly influence their efficacy and impact. This work’s rationale was that developing a simulator with greater physiologic accuracy and testing capabilities would improve the quantification of biomechanical parameters. This dissertation describes the development and validation of a simulator capable of performing passive assessments, which use experimenter manipulation, and active assessments – produced through muscle loading. Respectively, these allow the assessment of functional parameters such as stability, and kinematic/kinetic parameters including joint loading. The passive functionality enables specimen motion to be precisely controlled through independent manipulation of each rotational degree of freedom (DOF). Compared to unassisted manipulation, the system improved accuracy and repeatability of positioning the specimen (by 205% & 163%, respectively), decreased variation in DOF that are to remain constant (by 6.8°), and improved achievement of predefined endpoints (by 21%). Additionally, implementing a scapular rotation mechanism improved the physiologic accuracy of simulation. This enabled the clarification of the effect of secondary musculature on shoulder function, and the comparison of two competing clinical reconstructive procedures for shoulder instability. This was the first shoulder system to use real time kinematic feedback and PID control to produce active motion, which achieved unmatched accuracy ( These developments can be a powerful tool for increasing our understanding of the shoulder and also to provide information which can assist surgeons and improve patient outcomes

Advances and Trends in Mathematical Modelling, Control and Identification of Vibrating Systems

This book introduces novel results on mathematical modelling, parameter identification, and automatic control for a wide range of applications of mechanical, electric, and mechatronic systems, where undesirable oscillations or vibrations are manifested. The six chapters of the book written by experts from international scientific community cover a wide range of interesting research topics related to: algebraic identification of rotordynamic parameters in rotor-bearing system using finite element models; model predictive control for active automotive suspension systems by means of hydraulic actuators; model-free data-driven-based control for a Voltage Source Converter-based Static Synchronous Compensator to improve the dynamic power grid performance under transient scenarios; an exact elasto-dynamics theory for bending vibrations for a class of flexible structures; motion profile tracking control and vibrating disturbance suppression for quadrotor aerial vehicles using artificial neural networks and particle swarm optimization; and multiple adaptive controllers based on B-Spline artificial neural networks for regulation and attenuation of low frequency oscillations for large-scale power systems. The book is addressed for both academic and industrial researchers and practitioners, as well as for postgraduate and undergraduate engineering students and other experts in a wide variety of disciplines seeking to know more about the advances and trends in mathematical modelling, control and identification of engineering systems in which undesirable oscillations or vibrations could be presented during their operation

Vibration Suppression and Flywheel Energy Storage in a Drillstring Bottom-Hole-Assembly

In this study, a novel concept for a downhole flywheel energy storage module to be embedded in a bottom-hole-assembly (BHA) is presented and modeled, as an alternative power source to existing lithium-ion battery packs currently deployed in measurement-while-drilling (MWD) or logging-while-drilling (LWD) operations. Lithium-ion batteries disadvantages include deteriorated performance in high temperature, limited lifetime that necessitates frequent replacement which elevates operational costs, and environmental disposal. Extreme and harsh downhole conditions necessitate that the flywheel module withstands temperatures and pressures exceeding 300 ?F and 20 kpsi, respectively, as well as violent vibrations encountered during drilling. Moreover, the flywheel module should adhere to the geometric constraints of the wellbore and its corresponding BHA. Hence, a flywheel sizing procedure was developed that takes into consideration the required energy to be stored, the surrounding environmental conditions, and the geometric constraints. A five-axis magnetic levitation control system was implemented and tuned to maintain continuous suspension of the flywheel under the harsh lateral, axial and torsional drilling vibrations of the BHA. Thus, an integrated finite element model was developed that included the rotordynamic behavior of the flywheel and the BHA, the component dynamics of the magnetic levitation control system, and the cutting dynamics of the drillbit for both PDC and tricone types. The model also included a newly developed coupling between lateral, axial and torsional vibrations. It was demonstrated through simulations conducted by numerical integration that the flywheel maintains levitation due to all different types of external vibration as well as its own lateral vibration due to mass unbalance. Moreover, a passive proof-mass-damper (PPMD) was developed that suppresses axial bit-bounce vibrations as well as torsional vibrations, and was extended to also mitigate lateral vibrations. Optimized values of the mass, stiffness and damping values of the PPMD were obtained by the hybrid analytical-numerical Chebyshev spectral method that was superior in computational efficiency to iterative numerical integration. This also enabled the fine-plotting of an operating stability chart indicating stability regions where bit-bounce and stick-slip are avoided. The proof-mass-damping concept was extended to the flywheel to be an active proof-mass-damper (APMD) where simulations indicated functionality for a light-weight BHA

A Method to Calculate the Femoro-Polyethylene Contact Pressures in Total Knee Arthroplasty In-Vivo

This study deals with the development of a computational method that generates the in-vivo contact pressures on the superior side of the polyethylene in total knee arthroplasty (TKA) based on in-vivo kinematic data. Ten clinically successful subjects (five fixed and five mobile bearing TKA), having Hospital for Special Surgery (HSS) knee scores greater than 90, were analyzed under fluoroscopic surveillance while performing a weight-bearing deep knee bend. 3D in-vivo contact positions and kinematics, determined using a 2D to 3D registration technique, and soft tissue locations derived from literature were entered into a 3D inverse dynamics mathematical model to determine the in-vivo bearing contact forces. The contact areas were obtained by assembling the 3D CAD models of the components and measuring the interference area between them. The contact pressure was calculated by dividing the contact forces with the contact areas. For subjects with the mobile bearing TKA the average lateral contact forces varied from 0.34BW to 0.91BW and the average medial contact forces varied from 0.5BW to 2.7BW from full extension to full flexion. In subjects with the fixed bearing TKA the average contact forces ranged from 0.43BW to 0.92BW and from 1.04BW to 2.73BW on the lateral and medial sides respectively from full extension to full flexion. The contact areas for the mobile bearing TKA was always higher than the fixed bearing TKA. The average medial contact pressures ranged from 5.49MPa to 25.7MPa and from 12.8MPa to 34.38MPa for the mobile and fixed bearing TKA respectively. The average lateral contact pressures varied 3.08MPa to 18.83MPa and from 3.71MPa to 18.36MPa for the mobile and fixed bearing TKA respectively. This study reveals that the in-vivo contact forces and pressures are greater for the medial condyle than the lateral condyle, which is similar to polyethylene retrievals that demonstrate greater posterior-medial wear. Also the ability of the polyethylene insert, in mobile bearing TKA, to rotate helps in maintaining higher femoro-polyethylene contact areas resulting in lesser contact pressures compared to the fixed bearing TKA

Exotic Ground States and Dynamics in Constrained Systems

The overarching theme of this thesis is the question of how constraints influence collective behavior. Constraints are crucial in shaping both static and dynamic properties of systems across diverse areas within condensed matter physics and beyond. For example, the simple geometric constraint that hard particles cannot overlap at high density leads to slow dynamics and jamming in glass formers. Constraints also arise effectively at low temperature as a consequence of strong competing interactions in magnetic materials, where they give rise to emergent gauge theories and unconventional magnetic order. Enforcing constraints artificially in turn can be used to protect otherwise fragile quantum information from external noise. This thesis in particular contains progress on the realization of different unconventional phases of matter in constrained systems. The presentation of individual results is organized by the stage of realization of the respective phase. Novel physical phenomena after conceptualization are often exemplified in simple, heuristic models bearing little resemblance of actual matter, but which are interesting enough to motivate efforts with the final goal of realizing them in some way in the lab. One form of progress is then to devise refined models, which retain a degree of simplification while still realizing the same physics and improving the degree of realism in some direction. Finally, direct efforts in realizing either the original models or some refined version in experiment today are mostly two-fold. One route, having grown in importance rapidly during the last two decades, is via the engineering of artificial systems realizing suitable models. The other, more conventional way is to search for realizations of novel phases in materials. The thesis is divided into three parts, where Part I is devoted to the study of two simple models, while artificial systems and real materials are the subject of Part II and Part III respectively. Below, the content of each part is summarized in more detail. After a general introduction to entropic ordering and slow dynamics we present a family of models devised as a lattice analog of hard spheres. These are often studied to explore whether low-dimensional analogues of mean-field glass- and jamming transitions exist, but also serve as the canonical model systems for slow dynamics in granular materials more generally. Arguably the models in this family do not offer a close resemblance of actual granular materials. However, by studying their behavior far from equilibrium, we observe the onset of slow dynamics and a kinetic arrest for which, importantly, we obtain an essentially complete analytical and numerical understanding. Particularly interesting is the fact that this understanding hinges on the (in-)ability to anneal topological defects in the presence of a hardcore constraints, which resonates with some previous proposals for an understanding of the glass transition. As another example of anomalous dynamics arising in a magnetic system, we also present a detailed study of a two-dimensional fracton spin liquid. The model is an Ising system with an energy function designed to give rise to an emergent higher-rank gauge theory at low energy. We show explicitly that the number of zero-energy states in the model scales exponentially with the system size, establishing a finite residual entropy. A purpose-built cluster Monte-Carlo algorithm makes it possible to study the behavior of the model as a function of temperature. We show evidence for a first order transition from a high-temperature paramagnet to a low-temperature phase where correlations match predictions of a higher-rank coulomb phase. Turning away from heuristic models, the second part of the thesis begins with an introduction to quantum error correction, a scheme where constraints are artificially imposed in a quantum system through measurement and feedback. This is done in order to preserve quantum information in the presence of external noise, and is widely believed to be necessary in order to one day harness the full power of quantum computers. Given a certain error-correcting code as well as a noise model, a particularly interesting quantity is the threshold of the code, that is the critical amount of external noise below which quantum error correction becomes possible. For the toric code under independent bit- and phase-flip noise for example, the threshold is well known to map to the paramagnet to ferromagnet transition of the two-dimensional random-bond Ising model along the Nishimori line. Here, we present the first generalization of this mapping to a family of codes with finite rate, that is a family where the number of encoded logical qubits grows linearly with the number of physical qubits. In particular, we show that the threshold of hyperbolic surface codes maps to a paramagnet to ferromagnet transition in what we call the 'dual'' random-bond Ising model on regular tessellations of compact hyperbolic manifolds. This model is related to the usual random-bond Ising model by the Kramers-Wannier duality but distinct from it even on self-dual tessellations. As a corollary, we clarify long-standing issues regarding self-duality of the Ising model in hyperbolic space. The final part of the thesis is devoted to the study of material candidates of quantum spin ice, a three-dimensional quantum spin liquid. The work presented here was done in close collaboration with experiment and focuses on a particular family of materials called dipolar-octupolar pyrochlores. This family of materials is particularly interesting because they might realize novel exotic quantum states such as octupolar spin liquids, while at the same time being described by a relatively simple model Hamiltonian. This thesis contains a detailed study of ground state selection in dipolar-octupolar pyrochlore magnets and its signatures as observable in neutron scattering. First, we present evidence that the two compounds Ce2Zr2O7 and Ce2Sn2O7 despite their similar chemical composition realize an exotic quantum spin liquid state and an ordered state respectively. Then, we also study the ground-state selection in dipolar-octupolar pyrochlores in a magnetic field. Most importantly, we show that the well-known effective one-dimensional physics -- arising when the field is applied along a certain crystallographic axis -- is expected to be stable at experimentally relevant temperatures. Finally, we make predictions for neutron scattering in the large-field phase and compare these to measurements on Ce2Zr2O7

Inorganic Chiral Nanomaterials: Design Strategies and Their Properties

Interest in the synthesis of chiral nanostructures has been fueled by their prime fundamental and potential application of chiral nanostructures in biosensing, telecommunication, display technologies, diffraction-free patterning, and chiral catalysis. Although chirality is often associated with biochemistry due to numerous chiral biomolecules, today chiral inorganic nanostructures have attracted much attention, but their optical properties remain largely unexplored. Nanoscale inorganic chiral materials strongly rotate linear and circularly polarized light passing through them. Such optical effects are relatively easy to observe and are being actively investigated as a part of the study of chiral photonics and plasmonics. However, the opposite effects, the transfer of spin angular momenta of circularly polarized photons to materials and their subsequent nanoscale restructuring, are much less understood. In chapters II and III of this dissertation, I describe an experiment that demonstrates how circularly polarized light (CPL) affects dispersions of racemic nanoparticles (NPs). The intrinsic, non-covalent electrostatic, dipole-dipole, and van der Walls interactions, as well as hydrogen bonds between NPs combined to produce different types of NP superstructures. The transition from individual NPs to their superstructure assemblies can be easily controlled, visualized, and studied by different means. This strategy was applicable to various materials such as gold. By illuminating a seed-free gold ion dispersion with CPL, I could obtain optically active gold nanostructures. In chapter IV, I describe how I synthesized chiral cobalt oxide NPs using chiral molecules, namely, L- and D-cysteine as surface ligands. The chiral paramagnetic NPs showed ~ 10 times greater optical activity than other metal or semiconducting NPs of similar size. Moreover, the optical activities of the latter were mainly in the UV region while our NPs show practical activity in both the UV and visible ranges. The results of this study provide new opportunities for the design and synthesis of novel materials and contribute to a better understanding of materials at the nexus of magnetism and chirality.PHDMacromolecular Science & EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/140792/1/jyeom_1.pd

Geophysics for Mineral Exploration

This Special Issue contains ten papers which focus on emerging geophysical techniques for mineral exploration, novel modeling, and interpretation methods, including joint inversions of multi physics data, and challenging case studies. The papers cover a wide range of mineral deposits, including banded iron formations, epithermal gold–silver–copper–iron–molybdenum deposits, iron-oxide–copper–gold deposits, and prospecting forgroundwater resources

An Image-Based Tool to Examine Joint Congruency at the Elbow

Post-traumatic osteoarthritis commonly occurs as a result of a traumatic event to the articulation. Although the majority of this type of arthritis is preventable, the sequence and mechanism of the interaction between joint injury and the development of osteoarthritis (OA) is not well understood. It is hypothesized that alterations to the joint alignment can cause excessive and damaging wear to the cartilage surfaces resulting in OA. The lack of understanding of both the cause and progression of OA has contributed to the slow development of interventions which can modify the course of the disease. Currently, there have been no reported techniques that have been developed to examine the relationship between joint injury and joint alignment. Therefore, the objective of this thesis was to develop a non-invasive image-based technique that can be used to assess joint congruency and alignment of joints undergoing physiologic motion. An inter-bone distance algorithm was developed and validated to measure joint congruency at the ulnohumeral joint of the elbow. Subsequently, a registration algorithm was created and its accuracy was assessed. This registration algorithm registered 3D reconstructed bone models obtained using x-ray CT to motion capture data of cadaveric upper extremities undergoing simulated elbow flexion. In this way, the relative position and orientation of the 3D bone models could be visualized for any frame of motion. The effect of radial head arthroplasty was used to illustrate the utility of this technique. Once this registration was refined, the inter-bone distance algorithm was integrated to be able to visualize the joint congruency of the ulnohumeral joint undergoing simulated elbow flexion. The effect of collateral ligament repair was examined. This technique proved to be sensitive enough to detect large changes in joint congruency in spite of only small changes in the motion pathways of the ulnohumeral joint following simulated ligament repair. Efforts were also made in this thesis to translate this research into a clinical environment by examining CT scanning protocols that could reduce the amount of radiation exposure required to image patient’s joints. For this study, the glenohumeral joint of the shoulder was examined as this joint is particularly sensitive to potential harmful effects of radiation due to its proximity to highly radiosensitive organs. Using the CT scanning techniques examined in this thesis, the effective dose applied to the shoulder was reduced by almost 90% compared to standard clinical CT imaging. In summary, these studies introduced a technique that can be used to non-invasively and three-dimensionally examine joint congruency. The accuracy of this technique was assessed and its ability to predict regions of joint surface interactions was validated against a gold standard casting approach. Using the techniques developed in this thesis the complex relationship between injury, loading and mal-alignment as contributors to the development and progression of osteoarthritis in the upper extremity can be examined

The NASA SBIR product catalog

The purpose of this catalog is to assist small business firms in making the community aware of products emerging from their efforts in the Small Business Innovation Research (SBIR) program. It contains descriptions of some products that have advanced into Phase 3 and others that are identified as prospective products. Both lists of products in this catalog are based on information supplied by NASA SBIR contractors in responding to an invitation to be represented in this document. Generally, all products suggested by the small firms were included in order to meet the goals of information exchange for SBIR results. Of the 444 SBIR contractors NASA queried, 137 provided information on 219 products. The catalog presents the product information in the technology areas listed in the table of contents. Within each area, the products are listed in alphabetical order by product name and are given identifying numbers. Also included is an alphabetical listing of the companies that have products described. This listing cross-references the product list and provides information on the business activity of each firm. In addition, there are three indexes: one a list of firms by states, one that lists the products according to NASA Centers that managed the SBIR projects, and one that lists the products by the relevant Technical Topics utilized in NASA's annual program solicitation under which each SBIR project was selected

Quantum information with continuous variables

Quantum information is a rapidly advancing area of interdisciplinary research. It may lead to real-world applications for communication and computation unavailable without the exploitation of quantum properties such as nonorthogonality or entanglement. We review the progress in quantum information based on continuous quantum variables, with emphasis on quantum optical implementations in terms of the quadrature amplitudes of the electromagnetic field.Comment: accepted for publication in Reviews of Modern Physic