Fog Computing in Medical Internet-of-Things: Architecture, Implementation, and Applications

In the era when the market segment of Internet of Things (IoT) tops the chart in various business reports, it is apparently envisioned that the field of medicine expects to gain a large benefit from the explosion of wearables and internet-connected sensors that surround us to acquire and communicate unprecedented data on symptoms, medication, food intake, and daily-life activities impacting one's health and wellness. However, IoT-driven healthcare would have to overcome many barriers, such as: 1) There is an increasing demand for data storage on cloud servers where the analysis of the medical big data becomes increasingly complex, 2) The data, when communicated, are vulnerable to security and privacy issues, 3) The communication of the continuously collected data is not only costly but also energy hungry, 4) Operating and maintaining the sensors directly from the cloud servers are non-trial tasks. This book chapter defined Fog Computing in the context of medical IoT. Conceptually, Fog Computing is a service-oriented intermediate layer in IoT, providing the interfaces between the sensors and cloud servers for facilitating connectivity, data transfer, and queryable local database. The centerpiece of Fog computing is a low-power, intelligent, wireless, embedded computing node that carries out signal conditioning and data analytics on raw data collected from wearables or other medical sensors and offers efficient means to serve telehealth interventions. We implemented and tested an fog computing system using the Intel Edison and Raspberry Pi that allows acquisition, computing, storage and communication of the various medical data such as pathological speech data of individuals with speech disorders, Phonocardiogram (PCG) signal for heart rate estimation, and Electrocardiogram (ECG)-based Q, R, S detection.Comment: 29 pages, 30 figures, 5 tables. Keywords: Big Data, Body Area Network, Body Sensor Network, Edge Computing, Fog Computing, Medical Cyberphysical Systems, Medical Internet-of-Things, Telecare, Tele-treatment, Wearable Devices, Chapter in Handbook of Large-Scale Distributed Computing in Smart Healthcare (2017), Springe

Speech Enhancement Exploiting the Source-Filter Model

Imagining everyday life without mobile telephony is nowadays hardly possible. Calls are being made in every thinkable situation and environment. Hence, the microphone will not only pick up the user’s speech but also sound from the surroundings which is likely to impede the understanding of the conversational partner. Modern speech enhancement systems are able to mitigate such effects and most users are not even aware of their existence. In this thesis the development of a modern single-channel speech enhancement approach is presented, which uses the divide and conquer principle to combat environmental noise in microphone signals. Though initially motivated by mobile telephony applications, this approach can be applied whenever speech is to be retrieved from a corrupted signal. The approach uses the so-called source-filter model to divide the problem into two subproblems which are then subsequently conquered by enhancing the source (the excitation signal) and the filter (the spectral envelope) separately. Both enhanced signals are then used to denoise the corrupted signal. The estimation of spectral envelopes has quite some history and some approaches already exist for speech enhancement. However, they typically neglect the excitation signal which leads to the inability of enhancing the fine structure properly. Both individual enhancement approaches exploit benefits of the cepstral domain which offers, e.g., advantageous mathematical properties and straightforward synthesis of excitation-like signals. We investigate traditional model-based schemes like Gaussian mixture models (GMMs), classical signal processing-based, as well as modern deep neural network (DNN)-based approaches in this thesis. The enhanced signals are not used directly to enhance the corrupted signal (e.g., to synthesize a clean speech signal) but as so-called a priori signal-to-noise ratio (SNR) estimate in a traditional statistical speech enhancement system. Such a traditional system consists of a noise power estimator, an a priori SNR estimator, and a spectral weighting rule that is usually driven by the results of the aforementioned estimators and subsequently employed to retrieve the clean speech estimate from the noisy observation. As a result the new approach obtains significantly higher noise attenuation compared to current state-of-the-art systems while maintaining a quite comparable speech component quality and speech intelligibility. In consequence, the overall quality of the enhanced speech signal turns out to be superior as compared to state-of-the-art speech ehnahcement approaches.Mobiltelefonie ist aus dem heutigen Leben nicht mehr wegzudenken. Telefonate werden in beliebigen Situationen an beliebigen Orten geführt und dabei nimmt das Mikrofon nicht nur die Sprache des Nutzers auf, sondern auch die Umgebungsgeräusche, welche das Verständnis des Gesprächspartners stark beeinflussen können. Moderne Systeme können durch Sprachverbesserungsalgorithmen solchen Effekten entgegenwirken, dabei ist vielen Nutzern nicht einmal bewusst, dass diese Algorithmen existieren. In dieser Arbeit wird die Entwicklung eines einkanaligen Sprachverbesserungssystems vorgestellt. Der Ansatz setzt auf das Teile-und-herrsche-Verfahren, um störende Umgebungsgeräusche aus Mikrofonsignalen herauszufiltern. Dieses Verfahren kann für sämtliche Fälle angewendet werden, in denen Sprache aus verrauschten Signalen extrahiert werden soll. Der Ansatz nutzt das Quelle-Filter-Modell, um das ursprüngliche Problem in zwei Unterprobleme aufzuteilen, die anschließend gelöst werden, indem die Quelle (das Anregungssignal) und das Filter (die spektrale Einhüllende) separat verbessert werden. Die verbesserten Signale werden gemeinsam genutzt, um das gestörte Mikrofonsignal zu entrauschen. Die Schätzung von spektralen Einhüllenden wurde bereits in der Vergangenheit erforscht und zum Teil auch für die Sprachverbesserung angewandt. Typischerweise wird dabei jedoch das Anregungssignal vernachlässigt, so dass die spektrale Feinstruktur des Mikrofonsignals nicht verbessert werden kann. Beide Ansätze nutzen jeweils die Eigenschaften der cepstralen Domäne, die unter anderem vorteilhafte mathematische Eigenschaften mit sich bringen, sowie die Möglichkeit, Prototypen eines Anregungssignals zu erzeugen. Wir untersuchen modellbasierte Ansätze, wie z.B. Gaußsche Mischmodelle, klassische signalverarbeitungsbasierte Lösungen und auch moderne tiefe neuronale Netzwerke in dieser Arbeit. Die so verbesserten Signale werden nicht direkt zur Sprachsignalverbesserung genutzt (z.B. Sprachsynthese), sondern als sogenannter A-priori-Signal-zu-Rauschleistungs-Schätzwert in einem traditionellen statistischen Sprachverbesserungssystem. Dieses besteht aus einem Störleistungs-Schätzer, einem A-priori-Signal-zu-Rauschleistungs-Schätzer und einer spektralen Gewichtungsregel, die üblicherweise mit Hilfe der Ergebnisse der beiden Schätzer berechnet wird. Schließlich wird eine Schätzung des sauberen Sprachsignals aus der Mikrofonaufnahme gewonnen. Der neue Ansatz bietet eine signifikant höhere Dämpfung des Störgeräuschs als der bisherige Stand der Technik. Dabei wird eine vergleichbare Qualität der Sprachkomponente und der Sprachverständlichkeit gewährleistet. Somit konnte die Gesamtqualität des verbesserten Sprachsignals gegenüber dem Stand der Technik erhöht werden

Single- and multi-microphone speech dereverberation using spectral enhancement

In speech communication systems, such as voice-controlled systems, hands-free mobile telephones, and hearing aids, the received microphone signals are degraded by room reverberation, background noise, and other interferences. This signal degradation may lead to total unintelligibility of the speech and decreases the performance of automatic speech recognition systems. In the context of this work reverberation is the process of multi-path propagation of an acoustic sound from its source to one or more microphones. The received microphone signal generally consists of a direct sound, reflections that arrive shortly after the direct sound (commonly called early reverberation), and reflections that arrive after the early reverberation (commonly called late reverberation). Reverberant speech can be described as sounding distant with noticeable echo and colouration. These detrimental perceptual effects are primarily caused by late reverberation, and generally increase with increasing distance between the source and microphone. Conversely, early reverberations tend to improve the intelligibility of speech. In combination with the direct sound it is sometimes referred to as the early speech component. Reduction of the detrimental effects of reflections is evidently of considerable practical importance, and is the focus of this dissertation. More specifically the dissertation deals with dereverberation techniques, i.e., signal processing techniques to reduce the detrimental effects of reflections. In the dissertation, novel single- and multimicrophone speech dereverberation algorithms are developed that aim at the suppression of late reverberation, i.e., at estimation of the early speech component. This is done via so-called spectral enhancement techniques that require a specific measure of the late reverberant signal. This measure, called spectral variance, can be estimated directly from the received (possibly noisy) reverberant signal(s) using a statistical reverberation model and a limited amount of a priori knowledge about the acoustic channel(s) between the source and the microphone(s). In our work an existing single-channel statistical reverberation model serves as a starting point. The model is characterized by one parameter that depends on the acoustic characteristics of the environment. We show that the spectral variance estimator that is based on this model, can only be used when the source-microphone distance is larger than the so-called critical distance. This is, crudely speaking, the distance where the direct sound power is equal to the total reflective power. A generalization of the statistical reverberation model in which the direct sound is incorporated is developed. This model requires one additional parameter that is related to the ratio between the direct sound energy and the sound energy of all reflections. The generalized model is used to derive a novel spectral variance estimator. When the novel estimator is used for dereverberation rather than the existing estimator, and the source-microphone distance is smaller than the critical distance, the dereverberation performance is significantly increased. Single-microphone systems only exploit the temporal and spectral diversity of the received signal. Reverberation, of course, also induces spatial diversity. To additionally exploit this diversity, multiple microphones must be used, and their outputs must be combined by a suitable spatial processor such as the so-called delay and sum beamformer. It is not a priori evident whether spectral enhancement is best done before or after the spatial processor. For this reason we investigate both possibilities, as well as a merge of the spatial processor and the spectral enhancement technique. An advantage of the latter option is that the spectral variance estimator can be further improved. Our experiments show that the use of multiple microphones affords a significant improvement of the perceptual speech quality. The applicability of the theory developed in this dissertation is demonstrated using a hands-free communication system. Since hands-free systems are often used in a noisy and reverberant environment, the received microphone signal does not only contain the desired signal but also interferences such as room reverberation that is caused by the desired source, background noise, and a far-end echo signal that results from a sound that is produced by the loudspeaker. Usually an acoustic echo canceller is used to cancel the far-end echo. Additionally a post-processor is used to suppress background noise and residual echo, i.e., echo which could not be cancelled by the echo canceller. In this work a novel structure and post-processor for an acoustic echo canceller are developed. The post-processor suppresses late reverberation caused by the desired source, residual echo, and background noise. The late reverberation and late residual echo are estimated using the generalized statistical reverberation model. Experimental results convincingly demonstrate the benefits of the proposed system for suppressing late reverberation, residual echo and background noise. The proposed structure and post-processor have a low computational complexity, a highly modular structure, can be seamlessly integrated into existing hands-free communication systems, and affords a significant increase of the listening comfort and speech intelligibility

Speech Enhancement By Exploiting The Baseband Phase Structure Of Voiced Speech For Effective Non-Stationary Noise Estimation

Speech enhancement is one of the most important and challenging issues in the speech communication and signal processing field. It aims to minimize the effect of additive noise on the quality and intelligibility of the speech signal. Speech quality is the measure of noise remaining after the processing on the speech signal and of how pleasant the resulting speech sounds, while intelligibility refers to the accuracy of understanding speech. Speech enhancement algorithms are designed to remove the additive noise with minimum speech distortion.The task of speech enhancement is challenging due to lack of knowledge about the corrupting noise. Hence, the most challenging task is to estimate the noise which degrades the speech. Several approaches has been adopted for noise estimation which mainly fall under two categories: single channel algorithms and multiple channel algorithms. Due to this, the speech enhancement algorithms are also broadly classified as single and multiple channel enhancement algorithms.In this thesis, speech enhancement is studied in acoustic and modulation domains along with both amplitude and phase enhancement. We propose a noise estimation technique based on the spectral sparsity, detected by using the harmonic property of voiced segment of the speech. We estimate the frame to frame phase difference for the clean speech from available corrupted speech. This estimated frame-to-frame phase difference is used as a means of detecting the noise-only frequency bins even in voiced frames. This gives better noise estimation for the highly non-stationary noises like babble, restaurant and subway noise. This noise estimation along with the phase difference as an additional prior is used to extend the standard spectral subtraction algorithm. We also verify the effectiveness of this noise estimation technique when used with the Minimum Mean Squared Error Short Time Spectral Amplitude Estimator (MMSE STSA) speech enhancement algorithm. The combination of MMSE STSA and spectral subtraction results in further improvement of speech quality