317 research outputs found
Locally Adaptive Frames in the Roto-Translation Group and their Applications in Medical Imaging
Locally adaptive differential frames (gauge frames) are a well-known
effective tool in image analysis, used in differential invariants and
PDE-flows. However, at complex structures such as crossings or junctions, these
frames are not well-defined. Therefore, we generalize the notion of gauge
frames on images to gauge frames on data representations defined on the extended space of positions and
orientations, which we relate to data on the roto-translation group ,
. This allows to define multiple frames per position, one per
orientation. We compute these frames via exponential curve fits in the extended
data representations in . These curve fits minimize first or second
order variational problems which are solved by spectral decomposition of,
respectively, a structure tensor or Hessian of data on . We include
these gauge frames in differential invariants and crossing preserving PDE-flows
acting on extended data representation and we show their advantage compared
to the standard left-invariant frame on . Applications include
crossing-preserving filtering and improved segmentations of the vascular tree
in retinal images, and new 3D extensions of coherence-enhancing diffusion via
invertible orientation scores
Left-invariant evolutions of wavelet transforms on the Similitude Group
Enhancement of multiple-scale elongated structures in noisy image data is
relevant for many biomedical applications but commonly used PDE-based
enhancement techniques often fail at crossings in an image. To get an overview
of how an image is composed of local multiple-scale elongated structures we
construct a multiple scale orientation score, which is a continuous wavelet
transform on the similitude group, SIM(2). Our unitary transform maps the space
of images onto a reproducing kernel space defined on SIM(2), allowing us to
robustly relate Euclidean (and scaling) invariant operators on images to
left-invariant operators on the corresponding continuous wavelet transform.
Rather than often used wavelet (soft-)thresholding techniques, we employ the
group structure in the wavelet domain to arrive at left-invariant evolutions
and flows (diffusion), for contextual crossing preserving enhancement of
multiple scale elongated structures in noisy images. We present experiments
that display benefits of our work compared to recent PDE techniques acting
directly on the images and to our previous work on left-invariant diffusions on
orientation scores defined on Euclidean motion group.Comment: 40 page
Curvature Based Biomarkers for Diabetic Retinopathy via Exponential Curve Fits in SE(2)
We propose a robust and fully automatic method for the analysis of vessel tortuosity. Our method does not rely on pre-segmentation of vessels, but instead acts directly on retinal image data. The method is based on theory of best-fit exponential curves in the roto-translation group SE(2). We lift 2D images to 3D functions called orientation scores by including an orientation dimension in the domain. In the extended domain of positions and orientations (identified with SE(2)) we study exponential curves, whose spatial projections have constant curvature. By locally fitting such curves to data in orientation scores, via our new iterative stabilizing refinement method, we are able to assign to each location a curvature and confidence value. These values are then used to define global tortuosity measures. The method is validated on synthetic and retinal images. We show that the tortuosity measures can serve as effective biomarkers for diabetes and different stages of diabetic retinopathy
Nilpotent Approximations of Sub-Riemannian Distances for Fast Perceptual Grouping of Blood Vessels in 2D and 3D
We propose an efficient approach for the grouping of local orientations
(points on vessels) via nilpotent approximations of sub-Riemannian distances in
the 2D and 3D roto-translation groups and . In our distance
approximations we consider homogeneous norms on nilpotent groups that locally
approximate , and which are obtained via the exponential and logarithmic
map on . In a qualitative validation we show that the norms provide
accurate approximations of the true sub-Riemannian distances, and we discuss
their relations to the fundamental solution of the sub-Laplacian on .
The quantitative experiments further confirm the accuracy of the
approximations. Quantitative results are obtained by evaluating perceptual
grouping performance of retinal blood vessels in 2D images and curves in
challenging 3D synthetic volumes. The results show that 1) sub-Riemannian
geometry is essential in achieving top performance and 2) that grouping via the
fast analytic approximations performs almost equally, or better, than
data-adaptive fast marching approaches on and .Comment: 18 pages, 9 figures, 3 tables, in review at JMI
Geodesic Tracking via New Data-driven Connections of Cartan Type for Vascular Tree Tracking
We introduce a data-driven version of the plus Cartan connection on the
homogeneous space of 2D positions and orientations. We formulate
a theorem that describes all shortest and straight curves (parallel velocity
and parallel momentum, respectively) with respect to this new data-driven
connection and corresponding Riemannian manifold. Then we use these shortest
curves for geodesic tracking of complex vasculature in multi-orientation image
representations defined on . The data-driven Cartan connection
characterizes the Hamiltonian flow of all geodesics. It also allows for
improved adaptation to curvature and misalignment of the (lifted) vessel
structure that we track via globally optimal geodesics. We compute these
geodesics numerically via steepest descent on distance maps on
that we compute by a new modified anisotropic fast-marching method.
Our experiments range from tracking single blood vessels with fixed endpoints
to tracking complete vascular trees in retinal images. Single vessel tracking
is performed in a single run in the multi-orientation image representation,
where we project the resulting geodesics back onto the underlying image. The
complete vascular tree tracking requires only two runs and avoids prior
segmentation, placement of extra anchor points, and dynamic switching between
geodesic models.
Altogether we provide a geodesic tracking method using a single, flexible,
transparent, data-driven geodesic model providing globally optimal curves which
correctly follow highly complex vascular structures in retinal images.
All experiments in this article can be reproduced via documented Mathematica
notebooks available at GitHub
(https://github.com/NickyvdBerg/DataDrivenTracking)
Delineation of line patterns in images using B-COSFIRE filters
Delineation of line patterns in images is a basic step required in various
applications such as blood vessel detection in medical images, segmentation of
rivers or roads in aerial images, detection of cracks in walls or pavements,
etc. In this paper we present trainable B-COSFIRE filters, which are a model of
some neurons in area V1 of the primary visual cortex, and apply it to the
delineation of line patterns in different kinds of images. B-COSFIRE filters
are trainable as their selectivity is determined in an automatic configuration
process given a prototype pattern of interest. They are configurable to detect
any preferred line structure (e.g. segments, corners, cross-overs, etc.), so
usable for automatic data representation learning. We carried out experiments
on two data sets, namely a line-network data set from INRIA and a data set of
retinal fundus images named IOSTAR. The results that we achieved confirm the
robustness of the proposed approach and its effectiveness in the delineation of
line structures in different kinds of images.Comment: International Work Conference on Bioinspired Intelligence, July
10-13, 201
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