Self-paced Convolutional Neural Network for Computer Aided Detection in Medical Imaging Analysis

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various computer vision problems, there has been increasing work applying deep learning to medical image analysis. However, the development of a robust and reliable deep learning model for computer-aided diagnosis is still highly challenging due to the combination of the high heterogeneity in the medical images and the relative lack of training samples. Specifically, annotation and labeling of the medical images is much more expensive and time-consuming than other applications and often involves manual labor from multiple domain experts. In this work, we propose a multi-stage, self-paced learning framework utilizing a convolutional neural network (CNN) to classify Computed Tomography (CT) image patches. The key contribution of this approach is that we augment the size of training samples by refining the unlabeled instances with a self-paced learning CNN. By implementing the framework on high performance computing servers including the NVIDIA DGX1 machine, we obtained the experimental result, showing that the self-pace boosted network consistently outperformed the original network even with very scarce manual labels. The performance gain indicates that applications with limited training samples such as medical image analysis can benefit from using the proposed framework.Comment: accepted by 8th International Workshop on Machine Learning in Medical Imaging (MLMI 2017

Bootstrapped CNNs for Building Segmentation on RGB-D Aerial Imagery

Detection of buildings and other objects from aerial images has various applications in urban planning and map making. Automated building detection from aerial imagery is a challenging task, as it is prone to varying lighting conditions, shadows and occlusions. Convolutional Neural Networks (CNNs) are robust against some of these variations, although they fail to distinguish easy and difficult examples. We train a detection algorithm from RGB-D images to obtain a segmented mask by using the CNN architecture DenseNet.First, we improve the performance of the model by applying a statistical re-sampling technique called Bootstrapping and demonstrate that more informative examples are retained. Second, the proposed method outperforms the non-bootstrapped version by utilizing only one-sixth of the original training data and it obtains a precision-recall break-even of 95.10% on our aerial imagery dataset.Comment: Published at ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Science