Rib suppression in frontal chest radiographs: A blind source separation approach

Chest radiographs play an important role in the diagnosis of lung cancer. Detection of pulmonary nodules in chest radiographs forms the basis of early detection. Due to its sparse bone structure and overlapping of the nodule with ribs and clavicles the nodule is difficult to detect in conventional chest radiographs. We present a technique based on Independent Component Analysis (ICA) for the suppression of posterior ribs and clavicles which will en-hance the visibility of the nodules and aid the radiologist in diagnosis. 1

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology

Tuberculosis diagnosis from pulmonary chest x-ray using deep learning.

Doctoral Degree. University of KwaZulu-Natal, Durban.Tuberculosis (TB) remains a life-threatening disease, and it is one of the leading causes of mortality in developing countries. This is due to poverty and inadequate medical resources. While treatment for TB is possible, it requires an accurate diagnosis first. Several screening tools are available, and the most reliable is Chest X-Ray (CXR), but the radiological expertise for accurately interpreting the CXR images is often lacking. Over the years, CXR has been manually examined; this process results in delayed diagnosis, is time-consuming, expensive, and is prone to misdiagnosis, which could further spread the disease among individuals. Consequently, an algorithm could increase diagnosis efficiency, improve performance, reduce the cost of manual screening and ultimately result in early/timely diagnosis. Several algorithms have been implemented to diagnose TB automatically. However, these algorithms are characterized by low accuracy and sensitivity leading to misdiagnosis. In recent years, Convolutional Neural Networks (CNN), a class of Deep Learning, has demonstrated tremendous success in object detection and image classification task. Hence, this thesis proposed an efficient Computer-Aided Diagnosis (CAD) system with high accuracy and sensitivity for TB detection and classification. The proposed model is based firstly on novel end-to-end CNN architecture, then a pre-trained Deep CNN model that is fine-tuned and employed as a features extractor from CXR. Finally, Ensemble Learning was explored to develop an Ensemble model for TB classification. The Ensemble model achieved a new stateof- the-art diagnosis accuracy of 97.44% with a 99.18% sensitivity, 96.21% specificity and 0.96% AUC. These results are comparable with state-of-the-art techniques and outperform existing TB classification models.Author's Publications listed on page iii

Deep Learning in Chest Radiography: From Report Labeling to Image Classification

Chest X-ray (CXR) is the most common examination performed by a radiologist. Through CXR, radiologists must correctly and immediately diagnose a patient’s thorax to avoid the progression of life-threatening diseases. Not only are certified radiologists hard to find but also stress, fatigue, and lack of experience all contribute to the quality of an examination. As a result, providing a technique to aid radiologists in reading CXRs and a tool to help bridge the gap for communities without adequate access to radiological services would yield a huge advantage for patients and patient care. This thesis considers one essential task, CXR image classification, with Deep Learning (DL) technologies from the following three aspects: understanding the intersection of CXR interpretation and DL; extracting multiple image labels from radiology reports to facilitate the training of DL classifiers; and developing CXR classifiers using DL. First, we explain the core concepts and categorize the existing data and literature for researchers entering this field for ease of reference. Using CXRs and DL for medical image diagnosis is a relatively recent field of study because large, publicly available CXR datasets have not been around for very long. Second, we contribute to labeling large datasets with multi-label image annotations extracted from CXR reports. We describe the development of a DL-based report labeler named CXRlabeler, focusing on inductive sequential transfer learning. Lastly, we explain the design of three novel Convolutional Neural Network (CNN) classifiers, i.e., MultiViewModel, Xclassifier, and CovidXrayNet, for binary image classification, multi-label image classification, and multi-class image classification, respectively. This dissertation showcases significant progress in the field of automated CXR interpretation using DL; all source code used is publicly available. It provides methods and insights that can be applied to other medical image interpretation tasks

Recent Advances in Forensic Anthropological Methods and Research

Forensic anthropology, while still relatively in its infancy compared to other forensic science disciplines, adopts a wide array of methods from many disciplines for human skeletal identification in medico-legal and humanitarian contexts. The human skeleton is a dynamic tissue that can withstand the ravages of time given the right environment and may be the only remaining evidence left in a forensic case whether a week or decades old. Improved understanding of the intrinsic and extrinsic factors that modulate skeletal tissues allows researchers and practitioners to improve the accuracy and precision of identification methods ranging from establishing a biological profile such as estimating age-at-death, and population affinity, estimating time-since-death, using isotopes for geolocation of unidentified decedents, radiology for personal identification, histology to assess a live birth, to assessing traumatic injuries and so much more

CT Scanning

Since its introduction in 1972, X-ray computed tomography (CT) has evolved into an essential diagnostic imaging tool for a continually increasing variety of clinical applications. The goal of this book was not simply to summarize currently available CT imaging techniques but also to provide clinical perspectives, advances in hybrid technologies, new applications other than medicine and an outlook on future developments. Major experts in this growing field contributed to this book, which is geared to radiologists, orthopedic surgeons, engineers, and clinical and basic researchers. We believe that CT scanning is an effective and essential tools in treatment planning, basic understanding of physiology, and and tackling the ever-increasing challenge of diagnosis in our society

Advances on Scoliogeny, Diagnosis and Management of Scoliosis and Spinal Disorders

This book contains research articles on the advances in the aetiology of idiopathic scoliosis (IS), the spinal growth related to the implementation of growth modulation for the surgical treatment of early-onset IS, the non-surgical treatment of IS using Physiotheraputic Scoliosis Specific Exercises, and braces. Additionally, it focuses on issues related to surgical treatment, issues related to body posture and the quality of life of this sensitive group of people. The high quality of published papers in this Special Issue of the JCM serve these objectives

Validated respiratory drug deposition predictions from 2D and 3D medical images with statistical shape models and convolutional neural networks

37 pages main text (including frontmatter). 9 figures. Additional supplementary material. [v1] Thu, 2 Mar 2023 07:47:07 UTC (14,131 KB). The file archived on this institutional repository is an arXiv preprint. It may not have been certified by peer review.For the one billion sufferers of respiratory disease, managing their disease with inhalers crucially influences their quality of life. Generic treatment plans could be improved with the aid of computational models that account for patient-specific features such as breathing pattern, lung pathology and morphology. Therefore, we aim to develop and validate an automated computational framework for patient-specific deposition modelling. To that end, an image processing approach is proposed that could produce 3D patient respiratory geometries from 2D chest X-rays and 3D CT images. We evaluated the airway and lung morphology produced by our image processing framework, and assessed deposition compared to in vivo data. The 2D-to-3D image processing reproduces airway diameter to 9% median error compared to ground truth segmentations, but is sensitive to outliers of up to 33% due to lung outline noise. Predicted regional deposition gave 5% median error compared to in vivo measurements. The proposed framework is capable of providing patient-specific deposition measurements for varying treatments, to determine which treatment would best satisfy the needs imposed by each patient (such as disease and lung/airway morphology). Integration of patient-specific modelling into clinical practice as an additional decision-making tool could optimise treatment plans and lower the burden of respiratory diseases.Simulations reported in this study were performed on Oracle cloud computing platform, funded by Open Clouds Research Environments (OCRE) ‘Cloud Funding for Research’. JW was funded by a 2019 PhD Scholarship from the Carnegie-Trust for the Universities of Scotland. The in vivo deposition data used in this study was obtained from a project sponsored by Air Liquide