12 research outputs found

    Earth Resources: A continuing bibliography with indexes

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    This bibliography lists 623 reports, articles, and other documents introduced into the NASA scientific and technical information system between April 1 and June 30, 1983. Emphasis is placed on the use of remote sensing and geophysical instrumentation in spacecraft and aircraft to survey and inventory natural resources and urban areas. Subject matter is grouped according to agriculture and forestry, environmental changes and cultural resources, geodesy and cartography, geology and mineral resources, hydrology and water management, data processing and distribution systems, instrumentation and sensors, and economic analysis

    Retrieval of the Fine-Mode Aerosol Optical Depth over East China Using a Grouped Residual Error Sorting (GRES) Method from Multi-Angle and Polarized Satellite Data

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    The fine-mode aerosol optical depth (AODf) is an important parameter for the environment and climate change study, which mainly represents the anthropogenic aerosols component. The Polarization and Anisotropy of Reflectances for Atmospheric Science coupled with Observations from a Lidar (PARASOL) instrument can detect polarized signal from multi-angle observation and the polarized signal mainly comes from the radiation contribution of the fine-mode aerosols, which provides an opportunity to obtain AODf directly. However, the currently operational algorithm of Laboratoire d’Optique Atmosphérique (LOA) has a poor AODf retrieval accuracy over East China on high aerosol loading days. This study focused on solving this issue and proposed a grouped residual error sorting (GRES) method to determine the optimal aerosol model in AODf retrieval using the traditional look-up table (LUT) approach and then the AODf retrieval accuracy over East China was improved. The comparisons between the GRES retrieved and the Aerosol Robotic Network (AERONET) ground-based AODf at Beijing, Xianghe, Taihu and Hong_Kong_PolyU sites produced high correlation coefficients (r) of 0.900, 0.933, 0.957 and 0.968, respectively. The comparisons of the GRES retrieved AODf and PARASOL AODf product with those of the AERONET observations produced a mean absolute error (MAE) of 0.054 versus 0.104 on high aerosol loading days (AERONET mean AODf at 865 nm = 0.283). An application using the GRES method for total AOD (AODt) retrieval also showed a good expandability for multi-angle aerosol retrieval of this method

    Drug development progress in duchenne muscular dystrophy

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    Duchenne muscular dystrophy (DMD) is a severe, progressive, and incurable X-linked disorder caused by mutations in the dystrophin gene. Patients with DMD have an absence of functional dystrophin protein, which results in chronic damage of muscle fibers during contraction, thus leading to deterioration of muscle quality and loss of muscle mass over time. Although there is currently no cure for DMD, improvements in treatment care and management could delay disease progression and improve quality of life, thereby prolonging life expectancy for these patients. Furthermore, active research efforts are ongoing to develop therapeutic strategies that target dystrophin deficiency, such as gene replacement therapies, exon skipping, and readthrough therapy, as well as strategies that target secondary pathology of DMD, such as novel anti-inflammatory compounds, myostatin inhibitors, and cardioprotective compounds. Furthermore, longitudinal modeling approaches have been used to characterize the progression of MRI and functional endpoints for predictive purposes to inform Go/No Go decisions in drug development. This review showcases approved drugs or drug candidates along their development paths and also provides information on primary endpoints and enrollment size of Ph2/3 and Ph3 trials in the DMD space

    URI Undergraduate and Graduate Course Catalog 2015-2016

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1067/thumbnail.jp

    URI Undergraduate and Graduate Course Catalog 2014-2015

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1066/thumbnail.jp

    URI Undergraduate and Graduate Course Catalog 2016-2017

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1068/thumbnail.jp

    URI Undergraduate and Graduate Course Catalog 2018-2019

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1070/thumbnail.jp

    URI Undergraduate and Graduate Course Catalog 2019-2020

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1071/thumbnail.jp

    URI Undergraduate and Graduate Course Catalog 2017-2018

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    This is a downloadable PDF version of the University of Rhode Island course catalog.https://digitalcommons.uri.edu/course-catalogs/1069/thumbnail.jp
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