1,808 research outputs found
Retinal Vessel Segmentation Using the 2-D Morlet Wavelet and Supervised Classification
We present a method for automated segmentation of the vasculature in retinal
images. The method produces segmentations by classifying each image pixel as
vessel or non-vessel, based on the pixel's feature vector. Feature vectors are
composed of the pixel's intensity and continuous two-dimensional Morlet wavelet
transform responses taken at multiple scales. The Morlet wavelet is capable of
tuning to specific frequencies, thus allowing noise filtering and vessel
enhancement in a single step. We use a Bayesian classifier with
class-conditional probability density functions (likelihoods) described as
Gaussian mixtures, yielding a fast classification, while being able to model
complex decision surfaces and compare its performance with the linear minimum
squared error classifier. The probability distributions are estimated based on
a training set of labeled pixels obtained from manual segmentations. The
method's performance is evaluated on publicly available DRIVE and STARE
databases of manually labeled non-mydriatic images. On the DRIVE database, it
achieves an area under the receiver operating characteristic (ROC) curve of
0.9598, being slightly superior than that presented by the method of Staal et
al.Comment: 9 pages, 7 figures and 1 table. Accepted for publication in IEEE
Trans Med Imag; added copyright notic
Detection of curved lines with B-COSFIRE filters: A case study on crack delineation
The detection of curvilinear structures is an important step for various
computer vision applications, ranging from medical image analysis for
segmentation of blood vessels, to remote sensing for the identification of
roads and rivers, and to biometrics and robotics, among others. %The visual
system of the brain has remarkable abilities to detect curvilinear structures
in noisy images. This is a nontrivial task especially for the detection of thin
or incomplete curvilinear structures surrounded with noise. We propose a
general purpose curvilinear structure detector that uses the brain-inspired
trainable B-COSFIRE filters. It consists of four main steps, namely nonlinear
filtering with B-COSFIRE, thinning with non-maximum suppression, hysteresis
thresholding and morphological closing. We demonstrate its effectiveness on a
data set of noisy images with cracked pavements, where we achieve
state-of-the-art results (F-measure=0.865). The proposed method can be employed
in any computer vision methodology that requires the delineation of curvilinear
and elongated structures.Comment: Accepted at Computer Analysis of Images and Patterns (CAIP) 201
Joint segmentation and classification of retinal arteries/veins from fundus images
Objective Automatic artery/vein (A/V) segmentation from fundus images is
required to track blood vessel changes occurring with many pathologies
including retinopathy and cardiovascular pathologies. One of the clinical
measures that quantifies vessel changes is the arterio-venous ratio (AVR) which
represents the ratio between artery and vein diameters. This measure
significantly depends on the accuracy of vessel segmentation and classification
into arteries and veins. This paper proposes a fast, novel method for semantic
A/V segmentation combining deep learning and graph propagation.
Methods A convolutional neural network (CNN) is proposed to jointly segment
and classify vessels into arteries and veins. The initial CNN labeling is
propagated through a graph representation of the retinal vasculature, whose
nodes are defined as the vessel branches and edges are weighted by the cost of
linking pairs of branches. To efficiently propagate the labels, the graph is
simplified into its minimum spanning tree.
Results The method achieves an accuracy of 94.8% for vessels segmentation.
The A/V classification achieves a specificity of 92.9% with a sensitivity of
93.7% on the CT-DRIVE database compared to the state-of-the-art-specificity and
sensitivity, both of 91.7%.
Conclusion The results show that our method outperforms the leading previous
works on a public dataset for A/V classification and is by far the fastest.
Significance The proposed global AVR calculated on the whole fundus image
using our automatic A/V segmentation method can better track vessel changes
associated to diabetic retinopathy than the standard local AVR calculated only
around the optic disc.Comment: Preprint accepted in Artificial Intelligence in Medicin
A robust lesion boundary segmentation algorithm using level set methods
This paper addresses the issue of accurate lesion segmentation in retinal imagery, using level set methods and
a novel stopping mechanism - an elementary features scheme. Specifically, the curve propagation is guided
by a gradient map built using a combination of histogram equalization and robust statistics. The stopping
mechanism uses elementary features gathered as the curve deforms over time, and then using a lesionness
measure, defined herein, ’looks back in time’ to find the point at which the curve best fits the real object.
We compare the proposed method against five other
segmentation algorithms performed on 50 randomly selected images of exudates with a database of clinician
demarcated boundaries as ground truth
Lesion boundary segmentation using level set methods
This paper addresses the issue of accurate lesion segmentation in retinal imagery, using level set methods and
a novel stopping mechanism - an elementary features scheme. Specifically, the curve propagation is guided by a gradient map built using a combination of histogram equalization and robust statistics. The stopping mechanism uses elementary features gathered as the curve deforms over time, and then using a lesionness measure, defined herein, ’looks back in time’ to find the point at which the curve best fits the real object. We implement the level set using a fast upwind scheme and compare the proposed method against five other
segmentation algorithms performed on 50 randomly selected images of exudates with a database of clinician
marked-up boundaries as ground truth
Human treelike tubular structure segmentation: A comprehensive review and future perspectives
Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large collections of 2D and 3D images have been made available by medical imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), Optical coherence tomography (OCT) and ultrasound in which the spatial arrangement can be observed. Segmentation of these structures in medical imaging is of great importance since the analysis of the structure provides insights into disease diagnosis, treatment planning, and prognosis. Manually labelling extensive data by radiologists is often time-consuming and error-prone. As a result, automated or semi-automated computational models have become a popular research field of medical imaging in the past two decades, and many have been developed to date. In this survey, we aim to provide a comprehensive review of currently publicly available datasets, segmentation algorithms, and evaluation metrics. In addition, current challenges and future research directions are discussed
Automated retinal analysis
Diabetes is a chronic disease affecting over 2% of the population in the UK [1]. Long-term complications of diabetes can affect many different systems of the body including the retina of the eye. In the retina, diabetes can lead to a disease called diabetic retinopathy, one of the leading causes of blindness in the working population of industrialised countries. The risk of visual loss from diabetic retinopathy can be reduced if treatment is given at the onset of sight-threatening retinopathy. To detect early indicators of the disease, the UK National Screening Committee have recommended that diabetic patients should receive annual screening by digital colour fundal photography [2]. Manually grading retinal images is a subjective and costly process requiring highly skilled staff. This thesis describes an automated diagnostic system based oil image processing and neural network techniques, which analyses digital fundus images so that early signs of sight threatening retinopathy can be identified. Within retinal analysis this research has concentrated on the development of four algorithms: optic nerve head segmentation, lesion segmentation, image quality assessment and vessel width measurements. This research amalgamated these four algorithms with two existing techniques to form an integrated diagnostic system. The diagnostic system when used as a 'pre-filtering' tool successfully reduced the number of images requiring human grading by 74.3%: this was achieved by identifying and excluding images without sight threatening maculopathy from manual screening
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