HYDRA: Hybrid Deep Magnetic Resonance Fingerprinting

Purpose: Magnetic resonance fingerprinting (MRF) methods typically rely on dictio-nary matching to map the temporal MRF signals to quantitative tissue parameters. Such approaches suffer from inherent discretization errors, as well as high computational complexity as the dictionary size grows. To alleviate these issues, we propose a HYbrid Deep magnetic ResonAnce fingerprinting approach, referred to as HYDRA. Methods: HYDRA involves two stages: a model-based signature restoration phase and a learning-based parameter restoration phase. Signal restoration is implemented using low-rank based de-aliasing techniques while parameter restoration is performed using a deep nonlocal residual convolutional neural network. The designed network is trained on synthesized MRF data simulated with the Bloch equations and fast imaging with steady state precession (FISP) sequences. In test mode, it takes a temporal MRF signal as input and produces the corresponding tissue parameters. Results: We validated our approach on both synthetic data and anatomical data generated from a healthy subject. The results demonstrate that, in contrast to conventional dictionary-matching based MRF techniques, our approach significantly improves inference speed by eliminating the time-consuming dictionary matching operation, and alleviates discretization errors by outputting continuous-valued parameters. We further avoid the need to store a large dictionary, thus reducing memory requirements. Conclusions: Our approach demonstrates advantages in terms of inference speed, accuracy and storage requirements over competing MRF method

A regularized deep matrix factorized model of matrix completion for image restoration

It has been an important approach of using matrix completion to perform image restoration. Most previous works on matrix completion focus on the low-rank property by imposing explicit constraints on the recovered matrix, such as the constraint of the nuclear norm or limiting the dimension of the matrix factorization component. Recently, theoretical works suggest that deep linear neural network has an implicit bias towards low rank on matrix completion. However, low rank is not adequate to reflect the intrinsic characteristics of a natural image. Thus, algorithms with only the constraint of low rank are insufficient to perform image restoration well. In this work, we propose a Regularized Deep Matrix Factorized (RDMF) model for image restoration, which utilizes the implicit bias of the low rank of deep neural networks and the explicit bias of total variation. We demonstrate the effectiveness of our RDMF model with extensive experiments, in which our method surpasses the state of art models in common examples, especially for the restoration from very few observations. Our work sheds light on a more general framework for solving other inverse problems by combining the implicit bias of deep learning with explicit regularization

Image Restoration Using Very Deep Convolutional Encoder-Decoder Networks with Symmetric Skip Connections

In this paper, we propose a very deep fully convolutional encoding-decoding framework for image restoration such as denoising and super-resolution. The network is composed of multiple layers of convolution and de-convolution operators, learning end-to-end mappings from corrupted images to the original ones. The convolutional layers act as the feature extractor, which capture the abstraction of image contents while eliminating noises/corruptions. De-convolutional layers are then used to recover the image details. We propose to symmetrically link convolutional and de-convolutional layers with skip-layer connections, with which the training converges much faster and attains a higher-quality local optimum. First, The skip connections allow the signal to be back-propagated to bottom layers directly, and thus tackles the problem of gradient vanishing, making training deep networks easier and achieving restoration performance gains consequently. Second, these skip connections pass image details from convolutional layers to de-convolutional layers, which is beneficial in recovering the original image. Significantly, with the large capacity, we can handle different levels of noises using a single model. Experimental results show that our network achieves better performance than all previously reported state-of-the-art methods.Comment: Accepted to Proc. Advances in Neural Information Processing Systems (NIPS'16). Content of the final version may be slightly different. Extended version is available at http://arxiv.org/abs/1606.0892