The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases.

Model organisms are essential experimental platforms for discovering gene functions, defining protein and genetic networks, uncovering functional consequences of human genome variation, and for modeling human disease. For decades, researchers who use model organisms have relied on Model Organism Databases (MODs) and the Gene Ontology Consortium (GOC) for expertly curated annotations, and for access to integrated genomic and biological information obtained from the scientific literature and public data archives. Through the development and enforcement of data and semantic standards, these genome resources provide rapid access to the collected knowledge of model organisms in human readable and computation-ready formats that would otherwise require countless hours for individual researchers to assemble on their own. Since their inception, the MODs for the predominant biomedical model organisms [Mus sp (laboratory mouse), Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, Danio rerio, and Rattus norvegicus] along with the GOC have operated as a network of independent, highly collaborative genome resources. In 2016, these six MODs and the GOC joined forces as the Alliance of Genome Resources (the Alliance). By implementing shared programmatic access methods and data-specific web pages with a unified "look and feel," the Alliance is tackling barriers that have limited the ability of researchers to easily compare common data types and annotations across model organisms. To adapt to the rapidly changing landscape for evaluating and funding core data resources, the Alliance is building a modern, extensible, and operationally efficient "knowledge commons" for model organisms using shared, modular infrastructure

An Evaluation of the Effects of Dredging Within the Arkansas River Navigation System - Volume I - Introduction, Summary and Conclusions, and Recommendations

The foundation for the development of the Arkansas River was laid with the authorization of many upstream reservoirs in the comprehensive River and Harbor Act of 1946 signed by President Truman. Subsequent authorizations were forthcoming and work began on many of the bank stabilization facilities in 1950 and on the major structures in 1957. The current McClellan-Kerr Arkansas River Navigation System was substantially completed in 1972. The authorized multiple-purpose plan for the Arkansas River and tributaries provided for the construction of coordinated developments in the interests of navigation, hydroelectric power, flood control, bank stabilization, and related benefits including recreation and wildlife enhancement

Higher Education outreach to widen participation: toolkits for practitioners. Overview

The toolkits are a distillation of the learning, methods and resources developed by Aimhigher and the Lifelong Learning Network programmes to support the effective strategy, management and delivery of outreach work to encourage progression to higher education for under-represented groups. The toolkits recontextualise the learning from these programmes to fit the current higher education environment. The toolkits form a suite of four (see links to right). They include: • Toolkit 1 Partnership • Toolkit 2 Targeting • Toolkit 3 Programmes • Toolkit 4 Evaluation • Resources and glossary.This is the second and updated edition, the first edition of the Toolkits was published in December 2012.Higher Education Funding Council for England (HEFCE

CAHRS hrSpectrum (November-December 2008)

HRSpec2008_12.pdf: 478 downloads, before Oct. 1, 2020