Integrated Electronics for Wireless Imaging Microsystems with CMUT Arrays

Integration of transducer arrays with interface electronics in the form of single-chip CMUT-on-CMOS has emerged into the field of medical ultrasound imaging and is transforming this field. It has already been used in several commercial products such as handheld full-body imagers and it is being implemented by commercial and academic groups for Intravascular Ultrasound and Intracardiac Echocardiography. However, large attenuation of ultrasonic waves transmitted through the skull has prevented ultrasound imaging of the brain. This research is a prime step toward implantable wireless microsystems that use ultrasound to image the brain by bypassing the skull. These microsystems offer autonomous scanning (beam steering and focusing) of the brain and transferring data out of the brain for further processing and image reconstruction. The objective of the presented research is to develop building blocks of an integrated electronics architecture for CMUT based wireless ultrasound imaging systems while providing a fundamental study on interfacing CMUT arrays with their associated integrated electronics in terms of electrical power transfer and acoustic reflection which would potentially lead to more efficient and high-performance systems. A fully wireless architecture for ultrasound imaging is demonstrated for the first time. An on-chip programmable transmit (TX) beamformer enables phased array focusing and steering of ultrasound waves in the transmit mode while its on-chip bandpass noise shaping digitizer followed by an ultra-wideband (UWB) uplink transmitter minimizes the effect of path loss on the transmitted image data out of the brain. A single-chip application-specific integrated circuit (ASIC) is de- signed to realize the wireless architecture and interface with array elements, each of which includes a transceiver (TRX) front-end with a high-voltage (HV) pulser, a high-voltage T/R switch, and a low-noise amplifier (LNA). Novel design techniques are implemented in the system to enhance the performance of its building blocks. Apart from imaging capability, the implantable wireless microsystems can include a pressure sensing readout to measure intracranial pressure. To do so, a power-efficient readout for pressure sensing is presented. It uses pseudo-pseudo differential readout topology to cut down the static power consumption of the sensor for further power savings in wireless microsystems. In addition, the effect of matching and electrical termination on CMUT array elements is explored leading to new interface structures to improve bandwidth and sensitivity of CMUT arrays in different operation regions. Comprehensive analysis, modeling, and simulation methodologies are presented for further investigation.Ph.D

A HARDWARE-SOFTWARE CO-DESIGNED WEARABLE FOR REAL-TIME PHYSIOLOGICAL DATA COLLECTION AND SIGNAL QUALITY ASSESSMENT

In the future, Smart and Connected Communities (S&CC) will use distributed wireless sensors and embedded computing platforms to produce meaningful data that can help individuals, and communities. Here, we presented a scanner, a data reliability estimation algorithm and Electrocardiogram (ECG) beat classification algorithm which contributes to the S&CC framework .In part 1, we report the design, prototyping, and functional validation of a low-power, small, and portable signal acquisition device for these sensors. The scanner was fully tested, characterized, and validated in the lab, as well as through deployment to users homes. As a test case, we show results of the scanner measuring WRAP temperature sensors with relative error within the 0.01% range. The scanner measurement shows distinguish temperature of 1F difference and excellent linear dependence between actual and measured resistance (R2 = 0.998). This device hasdemonstrated the possibility of a small, low-power portable scanner for WRAP sensors.Additionally, we explored the statistical data reliability metric (DReM) to explain the quality of bio-signal quantitatively on a scale between 0.0 -1.0. As proof of concept, we analyzed the ECG signal. Our DReM prediction algorithm measures the reliability of the ECG signals effectively with low Root mean square error = 0.010 and Mean absolute error = 0.008 and coefficient of determination R2 value of 0.990. Finally, we tested our model against the opinions of three independent judges and presented R2 value to determine the agreement between judgments vs our prediction model.We concluded our contribution to the S&CC framework by analyzing ECG beat classification with a pipeline of classifiers that focuses on improving the models performance on identifying minority classes (ventricular ectopic beat, supraventricular ectopic beat). Moreover, we intended to minimize morphological distortion introduced due to indiscriminate use of filtering techniques on ECG signals. Our approach shows an average positive predictive value 95.21%, sensitivity of95.28%, and F-1 score 95.76% respectively

A 0.18µm CMOS UWB wireless transceiver for medical sensing applications

Recently, there is a new trend of demand of a biomedical device that can continuously monitor patient’s vital life index such as heart rate variability (HRV) and respiration rate. This desired device would be compact, wearable, wireless, networkable and low-power to enable proactive home monitoring of vital signs. This device should have a radar sensor portion and a wireless communication link all integrated in one small set. The promising technology that can satisfy these requirements is the impulse radio based Ultra-wideband (IR-UWB) technology. Since Federal Communications Commission (FCC) released the 3.1GHz-10.6GHz frequency band for UWB applications in 2002 [1], IR-UWB has received significant attention for applications in target positioning and wireless communications. IR-UWB employs extremely narrow Gaussian monocycle pulses or any other forms of short RF pulses to represent information. In this project, an integrated wireless UWB transceiver for the 3.1GHz-10.6GHz IR-UWB medical sensor was developed in the 0.18µm CMOS technology. This UWB transceiver can be employed for both radar sensing and communication purposes. The transceiver applies the On-Off Keying (OOK) modulation scheme to transmit short Gaussian pulse signals. The transmitter output power level is adjustable. The fully integrated UWB transceiver occupies a core area of 0.752mm^2 and the total die area of 1.274mm^2 with the pad ring inserted. The transceiver was simulated with overall power consumption of 40mW for radar sensing. The receiver is very sensitive to weak signals with a sensitivity of -73.01dBm. The average power of a single pulse is 9.8µW. The pulses are not posing any harm to human tissues. The sensing resolution and the target positioning precision are presumably sufficient for heart movement detection purpose in medical applications. This transceiver can also be used for high speed wireless data communications. The data transmission rate of 200 Mbps was achieved with an overall power consumption of 57mW. A combination of sensing and communications can be used to build a low power sensor

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Department of Electrical EngineeringA Sensor system is advanced along sensor technologies are developed. The performance improvement of sensor system can be expected by using the internet of things (IoT) communication technology and artificial neural network (ANN) for data processing and computation. Sensors or systems exchanged the data through this wireless connectivity, and various systems and applications are possible to implement by utilizing the advanced technologies. And the collected data is computed using by the ANN and the efficiency of system can be also improved. Gas monitoring system is widely need from the daily life to hazardous workplace. Harmful gas can cause a respiratory disease and some gas include cancer-causing component. Even though it may cause dangerous situation due to explosion. There are various kinds of hazardous gas and its characteristics that effect on human body are different each gas. The optimal design of gas monitoring system is necessary due to each gas has different criteria such as the permissible concentration and exposure time. Therefore, in this thesis, conventional sensor system configuration, operation, and limitation are described and gas monitoring system with wireless connectivity and neural network is proposed to improve the overall efficiency. As I already mentioned above, dangerous concentration and permissible exposure time are different depending on gas types. During the gas monitoring, gas concentration is lower than a permissible level in most of case. Thus, the gas monitoring is enough with low resolution for saving the power consumption in this situation. When detecting the gas, the high-resolution is required for the accurate concentration detecting. If the gas type is varied in the above situation, the amount of calculation increases exponentially. Therefore, in the conventional systems, target specifications are decided by the highest requirement in the whole situation, and it occurs increasing the cost and complexity of readout integrated circuit (ROIC) and system. In order to optimize the specification, the ANN and adaptive ROIC are utilized to compute the complex situation and huge data processing. Thus, gas monitoring system with learning-based algorithm is proposed to improve its efficiency. In order to optimize the operation depending on situation, dual-mode ROIC that monitoring mode and precision mode is implemented. If the present gas concentration is decided to safe, monitoring mode is operated with minimal detecting accuracy for saving the power consumption. The precision mode is switched when the high-resolution or hazardous situation are detected. The additional calibration circuits are necessary for the high-resolution implementation, and it has more power consumption and design complexity. A high-resolution Analog-to-digital converter (ADC) is kind of challenges to design with efficiency way. Therefore, in order to reduce the effective resolution of ADC and power consumption, zooming correlated double sampling (CDS) circuit and prediction successive approximation register (SAR) ADC are proposed for performance optimization into precision mode. A Microelectromechanical systems (MEMS) based gas sensor has high-integration and high sensitivity, but the calibration is needed to improve its low selectivity. Conventionally, principle component analysis (PCA) is used to classify the gas types, but this method has lower accuracy in some case and hard to verify in real-time. Alternatively, ANN is powerful algorithm to accurate sensing through collecting the data and training procedure and it can be verified the gas type and concentration in real-time. ROIC was fabricated in complementary metal-oxide-semiconductor (CMOS) 180-nm process and then the efficiency of the system with adaptive ROIC and ANN algorithm was experimentally verified into gas monitoring system prototype. Also, Bluetooth supports wireless connectivity to PC and mobile and pattern recognition and prediction code for SAR ADC is performed in MATLAB. Real-time gas information is monitored by Android-based application in smartphone. The dual-mode operation, optimization of performance and prediction code are adjusted with microcontroller unit (MCU). Monitoring mode is improved by x2.6 of figure-of-merits (FoM) that compared with previous resistive interface.clos

Smart Sensor Networks For Sensor-Neural Interface

One in every fifty Americans suffers from paralysis, and approximately 23% of paralysis cases are caused by spinal cord injury. To help the spinal cord injured gain functionality of their paralyzed or lost body parts, a sensor-neural-actuator system is commonly used. The system includes: 1) sensor nodes, 2) a central control unit, 3) the neural-computer interface and 4) actuators. This thesis focuses on a sensor-neural interface and presents the research related to circuits for the sensor-neural interface. In Chapter 2, three sensor designs are discussed, including a compressive sampling image sensor, an optical force sensor and a passive scattering force sensor. Chapter 3 discusses the design of the analog front-end circuit for the wireless sensor network system. A low-noise low-power analog front-end circuit in 0.5μm CMOS technology, a 12-bit 1MS/s successive approximation register (SAR) analog-to-digital converter (ADC) in 0.18μm CMOS process and a 6-bit asynchronous level-crossing ADC realized in 0.18μm CMOS process are presented. Chapter 4 shows the design of a low-power impulse-radio ultra-wide-band (IR-UWB) transceiver (TRx) that operates at a data rate of up to 10Mbps, with a power consumption of 4.9pJ/bit transmitted for the transmitter and 1.12nJ/bit received for the receiver. In Chapter 5, a wireless fully event-driven electrogoniometer is presented. The electrogoniometer is implemented using a pair of ultra-wide band (UWB) wireless smart sensor nodes interfacing with low power 3-axis accelerometers. The two smart sensor nodes are configured into a master node and a slave node, respectively. An experimental scenario data analysis shows higher than 90% reduction of the total data throughput using the proposed fully event-driven electrogoniometer to measure joint angle movements when compared with a synchronous Nyquist-rate sampling system. The main contribution of this thesis includes: 1) the sensor designs that emphasize power efficiency and data throughput efficiency; 2) the fully event-driven wireless sensor network system design that minimizes data throughput and optimizes power consumption

NASA Tech Briefs, October 2007

Topics covered include; Wirelessly Interrogated Position or Displacement Sensors; Ka-Band Radar Terminal Descent Sensor; Metal/Metal Oxide Differential Electrode pH Sensors; Improved Sensing Coils for SQUIDs; Inductive Linear-Position Sensor/Limit-Sensor Units; Hilbert-Curve Fractal Antenna With Radiation- Pattern Diversity; Single-Camera Panoramic-Imaging Systems; Interface Electronic Circuitry for an Electronic Tongue; Inexpensive Clock for Displaying Planetary or Sidereal Time; Efficient Switching Arrangement for (N + 1)/N Redundancy; Lightweight Reflectarray Antenna for 7.115 and 32 GHz; Opto-Electronic Oscillator Using Suppressed Phase Modulation; Alternative Controller for a Fiber-Optic Switch; Strong, Lightweight, Porous Materials; Nanowicks; Lightweight Thermal Protection System for Atmospheric Entry; Rapid and Quiet Drill; Hydrogen Peroxide Concentrator; MMIC Amplifiers for 90 to 130 GHz; Robot Would Climb Steep Terrain; Measuring Dynamic Transfer Functions of Cavitating Pumps; Advanced Resistive Exercise Device; Rapid Engineering of Three-Dimensional, Multicellular Tissues With Polymeric Scaffolds; Resonant Tunneling Spin Pump; Enhancing Spin Filters by Use of Bulk Inversion Asymmetry; Optical Magnetometer Incorporating Photonic Crystals; WGM-Resonator/Tapered-Waveguide White-Light Sensor Optics; Raman-Suppressing Coupling for Optical Parametric Oscillator; CO2-Reduction Primary Cell for Use on Venus; Cold Atom Source Containing Multiple Magneto- Optical Traps; POD Model Reconstruction for Gray-Box Fault Detection; System for Estimating Horizontal Velocity During Descent; Software Framework for Peer Data-Management Services; Autogen Version 2.0; Tracking-Data-Conversion Tool; NASA Enterprise Visual Analysis; Advanced Reference Counting Pointers for Better Performance; C Namelist Facility; and Efficient Mosaicking of Spitzer Space Telescope Images

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 43)

Abstracts are provided for 128 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1993 through Jun. 1993. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application

Sensor assembly, method, and device for monitoring shear force and pressure on a structure

Shear force and pressure on a structure are simultaneously monitored using signals received from sensors with antennas on the structure. For example, sensors and systems for monitoring shear force and pressure have applications including ulcer prevention associated with structures including shoes, prosthetics, wheel-chairs, and beds of bed-bound patients.Board of Regents, University of Texas Syste

Performance optimization of lateral-mode thin-film piezoelectric-on-substrate resonant systems

The main focus of this dissertation is to characterize and improve the performance of thin-film piezoelectric-on-substrate (TPoS) lateral-mode resonators and filters. TPoS is a class of piezoelectric MEMS devices which benefits from the high coupling coefficient of the piezoelectric transduction mechanism while taking advantage of superior acoustic properties of a substrate. The use of lateral-mode TPoS designs allows for fabrication of dispersed-frequency filters on a single substrate, thus significantly reducing the size and manufacturing cost of devices. TPoS filters also offer a lower temperature coefficient of frequency, and better power handling capability compared to rival technologies all in a very small footprint. Design and fabrication process of the TPoS devices is discussed. Both silicon and diamond substrates are utilized for fabrication of TPoS devices and results are compared. Specifically, the superior acoustic properties of nanocrystalline diamond in scaling the frequency and energy density of the resonators is highlighted in comparison with silicon. The performance of TPoS devices in a variety of applications is reported. These applications include lateral-mode TPoS filters with record low IL values (as low as 2dB) and fractional bandwidth up to 1%, impedance transformers, very low phase noise oscillators, and passive wireless temperature sensors

A Novel Power-Efficient Wireless Multi-channel Recording System for the Telemonitoring of Electroencephalography (EEG)

This research introduces the development of a novel EEG recording system that is modular, batteryless, and wireless (untethered) with the supporting theoretical foundation in wireless communications and related design elements and circuitry. Its modular construct overcomes the EEG scaling problem and makes it easier for reconfiguring the hardware design in terms of the number and placement of electrodes and type of standard EEG system contemplated for use. In this development, portability, lightweight, and applicability to other clinical applications that rely on EEG data are sought. Due to printer tolerance, the 3D printed cap consists of 61 electrode placements. This recording capacity can however extend from 21 (as in the international 10-20 systems) up to 61 EEG channels at sample rates ranging from 250 to 1000 Hz and the transfer of the raw EEG signal using a standard allocated frequency as a data carrier. The main objectives of this dissertation are to (1) eliminate the need for heavy mounted batteries, (2) overcome the requirement for bulky power systems, and (3) avoid the use of data cables to untether the EEG system from the subject for a more practical and less restrictive setting. Unpredictability and temporal variations of the EEG input make developing a battery-free and cable-free EEG reading device challenging. Professional high-quality and high-resolution analog front ends are required to capture non-stationary EEG signals at microvolt levels. The primary components of the proposed setup are the wireless power transmission unit, which consists of a power amplifier, highly efficient resonant-inductive link, rectification, regulation, and power management units, as well as the analog front end, which consists of an analog to digital converter, pre-amplification unit, filtering unit, host microprocessor, and the wireless communication unit. These must all be compatible with the rest of the system and must use the least amount of power possible while minimizing the presence of noise and the attenuation of the recorded signal A highly efficient resonant-inductive coupling link is developed to decrease power transmission dissipation. Magnetized materials were utilized to steer electromagnetic flux and decrease route and medium loss while transmitting the required energy with low dissipation. Signal pre-amplification is handled by the front-end active electrodes. Standard bio-amplifier design approaches are combined to accomplish this purpose, and a thorough investigation of the optimum ADC, microcontroller, and transceiver units has been carried out. We can minimize overall system weight and power consumption by employing battery-less and cable-free EEG readout system designs, consequently giving patients more comfort and freedom of movement. Similarly, the solutions are designed to match the performance of medical-grade equipment. The captured electrical impulses using the proposed setup can be stored for various uses, including classification, prediction, 3D source localization, and for monitoring and diagnosing different brain disorders. All the proposed designs and supporting mathematical derivations were validated through empirical and software-simulated experiments. Many of the proposed designs, including the 3D head cap, the wireless power transmission unit, and the pre-amplification unit, are already fabricated, and the schematic circuits and simulation results were based on Spice, Altium, and high-frequency structure simulator (HFSS) software. The fully integrated head cap to be fabricated would require embedding the active electrodes into the 3D headset and applying current technological advances to miniaturize some of the design elements developed in this dissertation