National Center for Biomedical Ontology: Advancing biomedicine through structured organization of scientific knowledge

The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease

Dimensions of Internet Commerce Trust

Trust is a central construct and plays a critical role in understanding Internet consumer behavior. This research seeks to directly address the subject of Internet Commerce Trust (ICT) by developing a valid, reliable, and generalizable scale to measure this multifaceted subject. Two separate studies reveal a common five-factor structure. These dimensions are labeled (1) Certification, (2) Resources and Capabilities, (3) Shopping Method, (4) Reliability, and (5) Communication Viability. An accurate measurement of ICT will serve as a viable control factor in future studies of Internet consumer behaviors, segmentation analyses, and in marketing strategy research

A new model for cross-cultural web design

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.People from different cultures use web interface in different ways, expect different visual representation, navigation, interaction, mental model, and layouts etc., and have different communication patterns and expectation. In the context of globalisation, web localisation becomes a powerful strategy to acquire an audience in a global market. Therefore, web developers and designers have to make adaptations to fit the needs of people from different cultures, and the way cultural factors are integrated into web interface design needs to be improved. Most previous research lacks an appropriate way to apply cultural factors into web development. No empirical study of the web interface has been carried out to support the cross-cultural web design model. It is noted that no single model can support all cross-cultural web communication but a new model is needed to bridge the gap and improve the limitations. Thus the research aim was to build a new model of cross-cultural web design to contribute to effective communication. Following an extensive literature review, a local web audit was conducted, then a series of experiments with users to gather and evaluate data and build and validate the new model. A new model, based on a study of British and Taiwanese users, was formulated and validated demonstrating that content and message remain the core of web design but the performance of the selected users is influenced by the cultural dimension and cultural preferences and this, in turn impacts on the effectiveness of the web communication. For the British user sample, ease of using the website was seen to be strongly related to desirability. Taiwanese users showed preference for visual pleasure but no relationship between efficient performance and desirability. The resultant model contributes to the knowledge of how to design effective web interfaces for British and Taiwanese cultures and is replicable for the purpose of comparing approaches to designing for other cultures

Alter ego, state of the art on user profiling: an overview of the most relevant organisational and behavioural aspects regarding User Profiling.

This report gives an overview of the most relevant organisational and\ud behavioural aspects regarding user profiling. It discusses not only the\ud most important aims of user profiling from both an organisation’s as\ud well as a user’s perspective, it will also discuss organisational motives\ud and barriers for user profiling and the most important conditions for\ud the success of user profiling. Finally recommendations are made and\ud suggestions for further research are given

Localization of Crowdfunding Platforms : The Influencing Role of Culture, Institutions and Geography

Master's thesis Business Administration BE501 - University of Agder 2019This master thesis examines the role played by culture, geography and institutions onEuropean crowdfunding platform’s decision to localize their content towards international markets. The authors conducted a binary logistic regression analysis is based on 470 observations of platform-country dyads collected from 269 European crowdfunding platforms and supplemented by additional sources of macro level indicators. Of the eleven hypotheses, social trust, geographical distance, high-context culture, rule of law and the investment orientation on platform have an effect on the decision to localize the platforms. IT infrastructure and the cultural dimensions of individualism, uncertainty avoidance, as well as a compounded variable of cultural distance, did not impact the same decision. The study’s findings are limited contextually to European crowdfunding platforms offering lending, equity, donation and reward-based models. Other micro-factors or countries of operation may exhibit different patterns than what is presented in this thesis. The study is one of the first in the field of localization andcrowdfunding, opening up for new discussions and insights. The results constitute and challenge the pre-existing theory on website localization. This thesis’ findings suggest that the context of this research is of significant impact as cultural adaptation has been highlighted to be one of the key factors to succeed in foreign markets in other industries

Digital Research Cycles: How Attitudes Toward Content, Culture And Technology Affect Web Development.

It has been estimated that one third of the world\u27s population does not have access to adequate health care. Some 1.6 billion people live in countries experiencing concentrated acquired immune deficiency syndrome (AIDS) epidemics. Many countries in Africa--and other low-income countries--are in dire need of help providing adequate health care services to their citizens. They require more hands-on care from Western health workers--and training so more African health workers can eventually care for their own citizens. But these countries also need assistance acquiring and implementing both texts--the body of medical information potentially available to them--and technology--the means by which that information can be conveyed. This dissertation looks at these issues and others from a multi-faceted approach. It combines a survey of the developers of Web sites designed for use by health workers in low-income countries and a proposal for a novel approach to communication theory, which could help improve health communication and other social marketing practices. It also includes an extensive review of literature regarding a number of topics related to these issues. To improve healthcare services in low-income countries, several things should occur. First, more health workers--and others--could visit African countries and other places to provide free, hands-on medical care, as this researcher\u27s group did in Uganda. Such trips are ideal occasions for studying the cultural differences between mzungu (white man) and the Ugandan people. A number of useful medical texts have been written for health workers in low-income countries. Others will be published as new health information becomes available. But on what medium will they be published? Computers? Personal digital assistants? During the past 10 years the Internet became an ideal venue for conveying information. Unfortunately, people in target countries such as Uganda encounter cultural differences when such new technologies are diffused. This dissertation looks at cultural and technological difficulties encountered by people in low-income countries who attempt to diffuse information and communication technologies (ICT). Once a technology has been successfully adopted, someone will look for ways to use it to help others. There are hundreds of sites on the Internet--built by Web developers in Western countries--that are designed for use by health workers in low-income countries. However, these Web developers also experience cultural and technological differences, based on their knowledge of and attitudes toward best practices in their field. This research includes a survey of Web developers which determined their attitudes toward best practices in their field and tested this researcher\u27s hypothesis that there is no significant difference among the developers\u27 attitudes toward the content on their sites, their audience\u27s cultural needs and the various technological needs their audience has. It was found that the Web developers agree with 17 of 18 perceived best practices and that there is a significant difference between Web developers\u27 attitudes toward their audience\u27s technological needs and their attitudes toward quality content and the audience\u27s cultural needs. Creation of the survey herein resulted in this researcher generating a new way of thinking about communication theory--called digital research cycles. The survey was based on a review of literature and is rooted in the belief that any successful communication of a computer-mediated message in the information age is a behavior which is influenced by the senders\u27 and receivers\u27 attitudes and knowledge about textual style, the audience, technology and the subject matter to which the message pertains

Does Online Course Design Encourage Attrition? Assessing Usability Factors in Learning Management Systems

Online coursework offers many college students flexibility and increased earning potential that they otherwise may not have due to personal or professional responsibilities and restrictions. Unfortunately, for students with disadvantaged technology backgrounds or disabilities limited accessibility compromises these opportunities for students who already face significant challenges to the completion of their post-secondary education. In the same manner that universal design of physical spaces increases usability of buildings and other facilities for all patrons, universal design of web-based courses could improve retention of course content for all learners. In a case study based on cognitive load theory and constructivist pedagogy, the researcher investigated the experience of postsecondary students with varying levels of technology background with user interface design of online courses, and how that design may inhibit the ability of these students to learn course content due to usability and accessibility issues. It was found that for students with the least technology background, course design could be an absolute barrier to successful course completion. Additionally, online courses with design features that deviate from common HTML standards and W3C norms can frustrate experienced users and also result in increased course attrition

Perceptions of Urban Pollution of River Dependent Rural Communities and Their Impact: A Case Study in Bangladesh

This study considers the Old Brahmaputra River, Bangladesh, as a case study regarding community perceptions on urban pollution and its impact on rural communities. In doing so, in-depth individual interviews (n = 195), key informant interviews (n = 7), and focus group discussions (n = 7) were conducted by emphasizing different perspectives on urban pollution and its effects on people related to losses of fisheries resources, agricultural production, human health, and livelihood transformation. The findings illustrate that poor urban solid waste management and direct sewage discharge degrade rivers daily. The most vulnerable rural communities are directly dependent upon the river, including fishermen, farmers, and boatmen. Specific measures such as an effluent treatment plant should be established near the river, and households and commercial drains should be cut off from the direct connection with the river. Alternative income-generating activities for the stakeholders are suggested to safeguard the river from urban pollution and the wellbeing of the stakeholders