Automatic Classification of Human Epithelial Type 2 Cell Indirect Immunofluorescence Images using Cell Pyramid Matching

This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol. The IIF protocol on HEp-2 cells has been the hallmark method to identify the presence of ANAs, due to its high sensitivity and the large range of antigens that can be detected. However, it suffers from numerous shortcomings, such as being subjective as well as time and labour intensive. Computer Aided Diagnostic (CAD) systems have been developed to address these problems, which automatically classify a HEp-2 cell image into one of its known patterns (eg. speckled, homogeneous). Most of the existing CAD systems use handpicked features to represent a HEp-2 cell image, which may only work in limited scenarios. We propose a novel automatic cell image classification method termed Cell Pyramid Matching (CPM), which is comprised of regional histograms of visual words coupled with the Multiple Kernel Learning framework. We present a study of several variations of generating histograms and show the efficacy of the system on two publicly available datasets: the ICPR HEp-2 cell classification contest dataset and the SNPHEp-2 dataset.Comment: arXiv admin note: substantial text overlap with arXiv:1304.126

KCRC-LCD: Discriminative Kernel Collaborative Representation with Locality Constrained Dictionary for Visual Categorization

We consider the image classification problem via kernel collaborative representation classification with locality constrained dictionary (KCRC-LCD). Specifically, we propose a kernel collaborative representation classification (KCRC) approach in which kernel method is used to improve the discrimination ability of collaborative representation classification (CRC). We then measure the similarities between the query and atoms in the global dictionary in order to construct a locality constrained dictionary (LCD) for KCRC. In addition, we discuss several similarity measure approaches in LCD and further present a simple yet effective unified similarity measure whose superiority is validated in experiments. There are several appealing aspects associated with LCD. First, LCD can be nicely incorporated under the framework of KCRC. The LCD similarity measure can be kernelized under KCRC, which theoretically links CRC and LCD under the kernel method. Second, KCRC-LCD becomes more scalable to both the training set size and the feature dimension. Example shows that KCRC is able to perfectly classify data with certain distribution, while conventional CRC fails completely. Comprehensive experiments on many public datasets also show that KCRC-LCD is a robust discriminative classifier with both excellent performance and good scalability, being comparable or outperforming many other state-of-the-art approaches

Improving Bag-of-Words model with spatial information

Bag-of-Words (BOW) models have recently become popular for the task of object recognition, owing to their good performance and simplicity. Much work has been proposed over the years to improve the BOW model, where the Spatial Pyramid Matching technique is the most notable. In this work, we propose three novel techniques to capture more re_ned spatial information between image features than that provided by the Spatial Pyramids. Our techniques demonstrate a performance gain over the Spatial Pyramid representation of the BOW model

DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs

In this work we address the task of semantic image segmentation with Deep Learning and make three main contributions that are experimentally shown to have substantial practical merit. First, we highlight convolution with upsampled filters, or 'atrous convolution', as a powerful tool in dense prediction tasks. Atrous convolution allows us to explicitly control the resolution at which feature responses are computed within Deep Convolutional Neural Networks. It also allows us to effectively enlarge the field of view of filters to incorporate larger context without increasing the number of parameters or the amount of computation. Second, we propose atrous spatial pyramid pooling (ASPP) to robustly segment objects at multiple scales. ASPP probes an incoming convolutional feature layer with filters at multiple sampling rates and effective fields-of-views, thus capturing objects as well as image context at multiple scales. Third, we improve the localization of object boundaries by combining methods from DCNNs and probabilistic graphical models. The commonly deployed combination of max-pooling and downsampling in DCNNs achieves invariance but has a toll on localization accuracy. We overcome this by combining the responses at the final DCNN layer with a fully connected Conditional Random Field (CRF), which is shown both qualitatively and quantitatively to improve localization performance. Our proposed "DeepLab" system sets the new state-of-art at the PASCAL VOC-2012 semantic image segmentation task, reaching 79.7% mIOU in the test set, and advances the results on three other datasets: PASCAL-Context, PASCAL-Person-Part, and Cityscapes. All of our code is made publicly available online.Comment: Accepted by TPAM