346,274 research outputs found

    SCF E3 Ligase Substrates Switch from CAN-D to Can-ubiquitylate

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    Liu et al. (2018) report a mathematical model predicting how the cellular repertoire of SCF E3 ligases is assembled by “adaptive exchange on demand,” with the limited pool of CUL1 scanning the vast sea of F-box proteins for those with substrates demanding ubiquitylation

    Council of the Baltic Sea States: The Role of a Sustainable and Prosperous Region in Bringing Science Diplomacy Forward. EL-CSID Working Paper Issue 2018/19 • July 2018

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    2017 has been a year full of promising major milestones for the future EU Science Diplomacy Strategy. At the beginning of 2017, the Directorate-General for Research and Innovation (DG RTD) of the European Commission released a thought-provoking report Tools for an EU science diplomacy (Van Langenhove, 2017). This publication was accompanied with a recognition among some parts of the academic circles and practitioners that the "Union is in process of reinforcing its diplomacy for science (the classical international S&T cooperation), while developing a genuine science for diplomacy" (López de San Román & Schunz, 2018, p. 262). Later on others have called the subsequent developments a worldwide "jump on the “science diplomacy” bandwagon" (Penca, 2018, p. 1). In the Baltic Sea Region setting, on 20 June 2017, the Reykjavík Ministerial of the Council of the Baltic Sea States (CBSS) took place and resulted in a Declaration on the Occasion of the 25th Anniversary of the CBSS (CBSS, 2017), as well as the endorsement of Realizing the Vision: Baltic 2030 Action Plan (CBSS Secretariat, 2017), which serves as "a solid basis for concrete CBSS action to meet the Sustainable Development Goals at regional level" (CBSS, 2017, p. 2). The report Tools for an EU science diplomacy outlines promising recommendations for further assembly of cases, which might serve as reference points or potential sources of inspiration once crafting the main structures and guidance enshrined in the upcoming 'EU Science Diplomacy Strategy'. As it will be outlined in subsequent paragraphs, the CBSS-endorsed multilateral cooperation initiatives have spurred various macro-regional dynamics of implicit science diplomacy,1 which might serve as a source of inspiration in the crafting of certain elements for the forthcoming strategy

    First data on microflora of loggerhead sea turtle (Caretta caretta) nests from the coastlines of Sicily

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    Caretta caretta is threatened by many dangers in the Mediterranean basin, but most are human-related. The purposes of this research were: (i) to investigate microflora in samples from six loggerhead sea turtle nests located on the Sicilian coast and (ii) to understand microbial diversity associated with nests, with particular attention to bacteria and fungi involved in failed hatchings. During the 2016 and 2018 summers, 456 eggs and seven dead hatchling from six nests were collected. We performed bacteriological and mycological analyses on 88 egg samples and seven dead hatchlings, allowing us to isolate: Fusarium spp. (80.6%), Aeromonas hydrophila (55.6%), Aspergillus spp. (27.2%) and Citrobacter freundii (9%). Two Fusarium species were identified by microscopy and were confirmed by PCR and internal transcribed spacer sequencing. Statistical analyses showed significant differences between nests and the presence/absence of microflora, whereas no significant differences were observed between eggs and nests. This is the first report that catalogues microflora from C. caretta nests/eggs in the Mediterranean Sea and provides key information on potential pathogens that may affect hatching success. Moreover, our results suggest the need for wider investigations over extensive areas to identify other microflora, and to better understand hatching failures and mortality related to microbial contamination in this important turtle species

    Protected Planet Report 2018

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    In 2010, Parties to the Convention on Biological Diversity (CBD) adopted a Strategic Plan for Biodiversity 2011-2020, including its 20 Aichi Biodiversity Targets, in order to address biodiversity loss, ensure the sustainable use of natural resources, and equitable sharing of benefits. The Protected Planet Report 2018 provides an update of progress towards Aichi Biodiversity Target 11 at the global scale. Each chapter of the report examines a specific element of Target 11. The findings in the report are based on data held in the World Database on Protected Areas (WDPA) as of July 2018. For the first time, the printed Protected Planet Report is complemented by an online version, regularly updated with all the latest data, which can be explored at the following address: www.livereport.protectedplanet.net. Since the Strategic Plan was adopted, there has been significant progress towards achieving elements of Aichi Target 11, particularly in terms of land and sea coverage. However, significant efforts are needed to achieve other elements of the target

    Life in Hampton Roads Survey Press Release #6: Sea Level Rise and Flooding

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    [Introductory paragraph] This report examines regional measures of environmental risk perceptions from the 2018 Life In Hampton Roads survey (LIHR 2018) conducted by the Old Dominion University Social Science Research Center. Data from prior years is also provided when available to show comparisons in responses over time. Responses were weighted by city population, race, age, gender, and phone usage (cell versus land-line) to be representative of the Hampton Roads region. For additional information on survey methodology, and analyses of other issues, please see the SSRC website at www.odu.edu/ssrc. The 2018 Life in Hampton Roads survey included a series of questions to determine how people in Hampton Roads felt about sea level rise and flooding, which supports a research focus of the University in this area. The survey asked the respondents to give their opinion on a variety of questions ranging from sea level rise to prevalence of recurrent flooding and other flood related topics

    Investing in America\u27s Surface Transportation Infrastructure: The Need for a Multi-Year Reauthorization Bill: Hearing Before the S. Comm. on Env\u27t & Pub. Works, 116th Cong., July 10, 2019

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    The Fourth National Climate Assessment, released in November 2018, described the serious impacts of climate change already being felt throughout the U.S., and made clear that the risks to communities all across the country are growing rapidly. These findings, along with those in the 2018 Intergovernmental Panel on Climate Change (IPCC) report should serve as an immediate call to action. Even if we manage to limit planetary warming to just 2 degrees Celsius, the world will still face increased chances of economic and social upheaval from more severe flooding, droughts, heatwaves, and other climate impacts as well as devastating environmental consequences, the IPCC report warns. The consensus from leading scientific research academies within the United States and internationally is clear: multiple lines of evidence indicate, and have indicated for years, that our atmosphere is warming, sea levels are rising, the magnitude and frequency of certain extreme weather events is increasing, and that human activity is the primary driver of climate change. As described in the IPCC Special Report, the consensus is that countries around the world must rapidly decarbonize their economies, cutting greenhouse gas emissions in half by 2030 and to near zero by 2050. The U.S. Department of Defense, and leaders within the defense and national security communities, have also recognized climate change as a “national security issue” that requires adapting military operations and planning to ensure readiness. Despite our understanding of the consequences we will face and the urgency to act, U.S. GHG emissions from fossil fuel combustion increased by 2.7 percent in 2018, according the Rhodium Group. Clearly more action is needed. While we all recognize the importance of transportation in our daily lives and for our economy, it is also important to recognize that the transportation sector is the largest contributor of GHG emissions in the United States, and is already facing significant impacts from climate change. There is an urgent need, therefore, to transition to a low-carbon and more resilient transportation system. Such a transition would not only reduce emissions and fight climate change, it also would bring additional important benefits, including protecting public health by reducing conventional air pollution, providing more mobility options, and driving innovation and economic growth through policy action and through public and private investment

    Feasibility Framing: Media Responses to the 2018 Intergovernmental Panel on Climate Change Special Report

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    With an associated warming of 0.85°C documented between 1880 and 2012, climate change has altered the frequency of extreme weather events, contributed to rising sea level, impacted biodiversity, and has become a growing concern (Allen et al. 53). Created in 1988, the Intergovernmental Panel on Climate Change (IPCC) compiles research on climate change for the use of policymaking. While the IPCC targets policymakers, the public generally learns science through media outlets (Schmidt et al.). On 8 October 2018, the IPCC released a special report titled, “Global Warming at 1.5°C.” Media outlets quickly responded to this report
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