Tautomeric mutation: A quantum spin modelling

A quantum spin model representing tautomeric mutation is proposed for any DNA molecule. Based on this model, the quantum mechanical calculations for mutational rate and complementarity restoring repair rate in the replication processes are carried out. A possible application to a real biological system is discussed.Comment: 7 pages (no figures

Quasistatic granular material rheology from particle simulations

We report on the quasistatic behaviour of model granular materials, as probed by DEM simulations of isotropic compression and triaxial compression tests, focussing on the macroscopic behaviour dependence on control parameters expressed in dimensionless forms that combine contact laws with test conditions, and on the influence of the initial state. A discussion of the microscopic origins of strain, which in some situations of small strains and stable contact networks are due to contact deflections, and in other cases results from the continuous breaking and repairing of networks under varying loads provides a useful classification of rheological regimes. Some guidelines for parameter choices in numerical simulations, and for some homogenization approaches, are inferre

Dynamic Analysis can be Improved with Automatic Test Suite Refactoring

Context: Developers design test suites to automatically verify that software meets its expected behaviors. Many dynamic analysis techniques are performed on the exploitation of execution traces from test cases. However, in practice, there is only one trace that results from the execution of one manually-written test case. Objective: In this paper, we propose a new technique of test suite refactoring, called B-Refactoring. The idea behind B-Refactoring is to split a test case into small test fragments, which cover a simpler part of the control flow to provide better support for dynamic analysis. Method: For a given dynamic analysis technique, our test suite refactoring approach monitors the execution of test cases and identifies small test cases without loss of the test ability. We apply B-Refactoring to assist two existing analysis tasks: automatic repair of if-statements bugs and automatic analysis of exception contracts. Results: Experimental results show that test suite refactoring can effectively simplify the execution traces of the test suite. Three real-world bugs that could previously not be fixed with the original test suite are fixed after applying B-Refactoring; meanwhile, exception contracts are better verified via applying B-Refactoring to original test suites. Conclusions: We conclude that applying B-Refactoring can effectively improve the purity of test cases. Existing dynamic analysis tasks can be enhanced by test suite refactoring