18,802 research outputs found
Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates
The study of cerebral anatomy in developing neonates is of great importance for
the understanding of brain development during the early period of life. This
dissertation therefore focuses on three challenges in the modelling of cerebral
anatomy in neonates during brain development. The methods that have been
developed all use Magnetic Resonance Images (MRI) as source data.
To facilitate study of vascular development in the neonatal period, a set of image
analysis algorithms are developed to automatically extract and model cerebral
vessel trees. The whole process consists of cerebral vessel tracking from
automatically placed seed points, vessel tree generation, and vasculature
registration and matching. These algorithms have been tested on clinical Time-of-
Flight (TOF) MR angiographic datasets.
To facilitate study of the neonatal cortex a complete cerebral cortex segmentation
and reconstruction pipeline has been developed. Segmentation of the neonatal
cortex is not effectively done by existing algorithms designed for the adult brain
because the contrast between grey and white matter is reversed. This causes pixels
containing tissue mixtures to be incorrectly labelled by conventional methods. The
neonatal cortical segmentation method that has been developed is based on a novel
expectation-maximization (EM) method with explicit correction for mislabelled
partial volume voxels. Based on the resulting cortical segmentation, an implicit
surface evolution technique is adopted for the reconstruction of the cortex in
neonates. The performance of the method is investigated by performing a detailed
landmark study.
To facilitate study of cortical development, a cortical surface registration algorithm
for aligning the cortical surface is developed. The method first inflates extracted
cortical surfaces and then performs a non-rigid surface registration using free-form
deformations (FFDs) to remove residual alignment. Validation experiments using
data labelled by an expert observer demonstrate that the method can capture local
changes and follow the growth of specific sulcus
Nonrigid reconstruction of 3D breast surfaces with a low-cost RGBD camera for surgical planning and aesthetic evaluation
Accounting for 26% of all new cancer cases worldwide, breast cancer remains
the most common form of cancer in women. Although early breast cancer has a
favourable long-term prognosis, roughly a third of patients suffer from a
suboptimal aesthetic outcome despite breast conserving cancer treatment.
Clinical-quality 3D modelling of the breast surface therefore assumes an
increasingly important role in advancing treatment planning, prediction and
evaluation of breast cosmesis. Yet, existing 3D torso scanners are expensive
and either infrastructure-heavy or subject to motion artefacts. In this paper
we employ a single consumer-grade RGBD camera with an ICP-based registration
approach to jointly align all points from a sequence of depth images
non-rigidly. Subtle body deformation due to postural sway and respiration is
successfully mitigated leading to a higher geometric accuracy through
regularised locally affine transformations. We present results from 6 clinical
cases where our method compares well with the gold standard and outperforms a
previous approach. We show that our method produces better reconstructions
qualitatively by visual assessment and quantitatively by consistently obtaining
lower landmark error scores and yielding more accurate breast volume estimates
Finite Element Based Tracking of Deforming Surfaces
We present an approach to robustly track the geometry of an object that
deforms over time from a set of input point clouds captured from a single
viewpoint. The deformations we consider are caused by applying forces to known
locations on the object's surface. Our method combines the use of prior
information on the geometry of the object modeled by a smooth template and the
use of a linear finite element method to predict the deformation. This allows
the accurate reconstruction of both the observed and the unobserved sides of
the object. We present tracking results for noisy low-quality point clouds
acquired by either a stereo camera or a depth camera, and simulations with
point clouds corrupted by different error terms. We show that our method is
also applicable to large non-linear deformations.Comment: additional experiment
Point clouds by SLAM-based mobile mapping systems: accuracy and geometric content validation in multisensor survey and stand-alone acquisition
The paper provides some operative replies to evaluate the effectiveness and the critical issues of the simultaneous localisation and mapping (SLAM)-based mobile mapping system (MMS) called ZEB by GeoSLAMâ„¢ https://geoslam.com/technology/. In these last years, this type of handheld 3D mapping technology has increasingly developed the framework of portable solutions for close-range mapping systems that have mainly been devoted to mapping the indoor building spaces of enclosed or underground environments, such as forestry applications and tunnels or mines. The research introduces a set of test datasets related to the documentation of landscape contexts or the 3D modelling of architectural complexes. These datasets are used to validate the accuracy and informative content richness about ZEB point clouds in stand-alone solutions and in cases of combined applications of this technology with multisensor survey approaches. In detail, the proposed validation method follows the fulfilment of the endorsed approach by use of root mean square error (RMSE) evaluation and deviation analysis assessment of point clouds between SLAM-based data and 3D point cloud surfaces computed by more precise measurement methods to evaluate the accuracy of the proposed approach. Furthermore, this study specifies the suitable scale for possible handlings about these peculiar point clouds and uses the profile extraction method in addition to feature analyses such as corner and plane deviation analysis of architectural elements. Finally, because of the experiences reported in the literature and performed in this work, a possible reversal is suggested. If in the 2000s, most studies focused on intelligently reducing the light detection and ranging (LiDAR) point clouds where they presented redundant and not useful information, contrariwise, in this sense, the use of MMS methods is proposed to be firstly considered and then to increase the information only wherever needed with more accurate high-scale methods
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State of the Art of Level Set Methods in Segmentation and Registration of Medical Imaging Modalities
Segmentation of medical images is an important step in various applications such as visualization, quantitative analysis and image-guided surgery. Numerous segmentation methods have been developed in the past two decades for extraction of organ contours on medical images. Low-level segmentation methods, such as pixel-based clustering, region growing, and filter-based edge detection, require additional pre-processing and post-processing as well as considerable amounts of expert intervention or information of the objects of interest. Furthermore the subsequent analysis of segmented objects is hampered by the primitive, pixel or voxel level representations from those region-based segmentation. Deformable models, on the other hand, provide an explicit representation of the boundary and the shape of the object. They combine several desirable features such as inherent connectivity and smoothness, which counteract noise and boundary irregularities, as well as the ability to incorporate knowledge about the object of interest. However, parametric deformable models have two main limitations. First, in situations where the initial model and desired object boundary differ greatly in size and shape, the model must be re-parameterized dynamically to faithfully recover the object boundary. The second limitation is that it has difficulty dealing with topological adaptation such as splitting or merging model parts, a useful property for recovering either multiple objects or objects with unknown topology. This difficulty is caused by the fact that a new parameterization must be constructed whenever topology change occurs, which requires sophisticated schemes. Level set deformable models, also referred to as geometric deformable models, provide an elegant solution to address the primary limitations of parametric deformable models. These methods have drawn a great deal of attention since their introduction in 1988. Advantages of the contour implicit formulation of the deformable model over parametric formulation include: (1) no parameterization of the contour, (2) topological flexibility, (3) good numerical stability, (4) straightforward extension of the 2D formulation to n-D. Recent reviews on the subject include papers from Suri. In this chapter we give a general overview of the level set segmentation methods with emphasize on new frameworks recently introduced in the context of medical imaging problems. We then introduce novel approaches that aim at combining segmentation and registration in a level set formulation. Finally we review a selective set of clinical works with detailed validation of the level set methods for several clinical applications
Geometric Convolutional Neural Network for Analyzing Surface-Based Neuroimaging Data
The conventional CNN, widely used for two-dimensional images, however, is not
directly applicable to non-regular geometric surface, such as a cortical
thickness. We propose Geometric CNN (gCNN) that deals with data representation
over a spherical surface and renders pattern recognition in a multi-shell mesh
structure. The classification accuracy for sex was significantly higher than
that of SVM and image based CNN. It only uses MRI thickness data to classify
gender but this method can expand to classify disease from other MRI or fMRI
dataComment: 29 page
Model of a Vascular C-Arm for 3D Augmented Fluoroscopy in Interventional Radiology
International audienceThis paper deals with the modeling of a vascular C-arm to generate 3D augmented fuoroscopic images in an interventional radiology context. A methodology based on the use of a multi-image calibration is proposed to assess the physical behavior of the C-arm. From the knowledge of the main characteristics of the C-arm, realistic models of the acquisition geometry are proposed. Their accuracy was evaluated and experiments showed that the C-arm geometry can be predicted with a mean 2D reprojection error of 0.5 mm. The interest of 3D augmented uoroscopy is also assessed on a clinical case
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