66,417 research outputs found
Learning to Rank Academic Experts in the DBLP Dataset
Expert finding is an information retrieval task that is concerned with the
search for the most knowledgeable people with respect to a specific topic, and
the search is based on documents that describe people's activities. The task
involves taking a user query as input and returning a list of people who are
sorted by their level of expertise with respect to the user query. Despite
recent interest in the area, the current state-of-the-art techniques lack in
principled approaches for optimally combining different sources of evidence.
This article proposes two frameworks for combining multiple estimators of
expertise. These estimators are derived from textual contents, from
graph-structure of the citation patterns for the community of experts, and from
profile information about the experts. More specifically, this article explores
the use of supervised learning to rank methods, as well as rank aggregation
approaches, for combing all of the estimators of expertise. Several supervised
learning algorithms, which are representative of the pointwise, pairwise and
listwise approaches, were tested, and various state-of-the-art data fusion
techniques were also explored for the rank aggregation framework. Experiments
that were performed on a dataset of academic publications from the Computer
Science domain attest the adequacy of the proposed approaches.Comment: Expert Systems, 2013. arXiv admin note: text overlap with
arXiv:1302.041
Strategies for Searching Video Content with Text Queries or Video Examples
The large number of user-generated videos uploaded on to the Internet
everyday has led to many commercial video search engines, which mainly rely on
text metadata for search. However, metadata is often lacking for user-generated
videos, thus these videos are unsearchable by current search engines.
Therefore, content-based video retrieval (CBVR) tackles this metadata-scarcity
problem by directly analyzing the visual and audio streams of each video. CBVR
encompasses multiple research topics, including low-level feature design,
feature fusion, semantic detector training and video search/reranking. We
present novel strategies in these topics to enhance CBVR in both accuracy and
speed under different query inputs, including pure textual queries and query by
video examples. Our proposed strategies have been incorporated into our
submission for the TRECVID 2014 Multimedia Event Detection evaluation, where
our system outperformed other submissions in both text queries and video
example queries, thus demonstrating the effectiveness of our proposed
approaches
Assessing the Prosody of Non-Native Speakers of English: Measures and Feature Sets
In this paper, we describe a new database with audio recordings of non-native (L2) speakers of English, and the perceptual evaluation experiment conducted with native English speakers for assessing the prosody of each recording. These annotations are then used to compute the gold standard using different methods, and a series of regression experiments is conducted to evaluate their impact on the performance of a regression model predicting the degree of Abstract naturalness of L2 speech. Further, we compare the relevance of different feature groups modelling prosody in general (without speech tempo), speech rate and pauses modelling speech tempo (fluency), voice quality, and a variety of spectral features. We also discuss the impact of various fusion strategies on performance.Overall, our results demonstrate that the prosody of non-native speakers of English as L2 can be reliably assessed using supra- segmental audio features; prosodic features seem to be the most important ones
A Deep Spatio-Temporal Fuzzy Neural Network for Passenger Demand Prediction
In spite of its importance, passenger demand prediction is a highly
challenging problem, because the demand is simultaneously influenced by the
complex interactions among many spatial and temporal factors and other external
factors such as weather. To address this problem, we propose a Spatio-TEmporal
Fuzzy neural Network (STEF-Net) to accurately predict passenger demands
incorporating the complex interactions of all known important factors. We
design an end-to-end learning framework with different neural networks modeling
different factors. Specifically, we propose to capture spatio-temporal feature
interactions via a convolutional long short-term memory network and model
external factors via a fuzzy neural network that handles data uncertainty
significantly better than deterministic methods. To keep the temporal relations
when fusing two networks and emphasize discriminative spatio-temporal feature
interactions, we employ a novel feature fusion method with a convolution
operation and an attention layer. As far as we know, our work is the first to
fuse a deep recurrent neural network and a fuzzy neural network to model
complex spatial-temporal feature interactions with additional uncertain input
features for predictive learning. Experiments on a large-scale real-world
dataset show that our model achieves more than 10% improvement over the
state-of-the-art approaches.Comment: https://epubs.siam.org/doi/abs/10.1137/1.9781611975673.1
INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE
Transcriptomic profiling and gene expression signatures have been widely applied as effective approaches for enhancing the molecular classification, diagnosis, prognosis or prediction of therapeutic response towards personalized therapy for cancer patients. Thanks to modern genome-wide profiling technology, scientists are able to build engines leveraging massive genomic variations and integrating with clinical data to identify “at risk” individuals for the sake of prevention, diagnosis and therapeutic interventions. In my graduate work for my Ph.D. thesis, I have investigated genomic sequencing data mining to comprehensively characterise molecular classifications and aberrant genomic events associated with clinical prognosis and treatment response, through applying high-dimensional omics genomic data to promote the understanding of gene signatures and somatic molecular alterations contributing to cancer progression and clinical outcomes. Following this motivation, my dissertation has been focused on the following three topics in translational genomics.
1) Characterization of transcriptomic plasticity and its association with the tumor microenvironment in glioblastoma (GBM). I have integrated transcriptomic, genomic, protein and clinical data to increase the accuracy of GBM classification, and identify the association between the GBM mesenchymal subtype and reduced tumorpurity, accompanied with increased presence of tumor-associated microglia. Then I have tackled the sole source of microglial as intrinsic tumor bulk but not their corresponding neurosphere cells through both transcriptional and protein level analysis using a panel of sphere-forming glioma cultures and their parent GBM samples.FurthermoreI have demonstrated my hypothesis through longitudinal analysis of paired primary and recurrent GBM samples that the phenotypic alterations of GBM subtypes are not due to intrinsic proneural-to-mesenchymal transition in tumor cells, rather it is intertwined with increased level of microglia upon disease recurrence. Collectively I have elucidated the critical role of tumor microenvironment (Microglia and macrophages from central nervous system) contributing to the intra-tumor heterogeneity and accurate classification of GBM patients based on transcriptomic profiling, which will not only significantly impact on clinical perspective but also pave the way for preclinical cancer research.
2) Identification of prognostic gene signatures that stratify adult diffuse glioma patientsharboring1p/19q co-deletions. I have compared multiple statistical methods and derived a gene signature significantly associated with survival by applying a machine learning algorithm. Then I have identified inflammatory response and acetylation activity that associated with malignant progression of 1p/19q co-deleted glioma. In addition, I showed this signature translates to other types of adult diffuse glioma, suggesting its universality in the pathobiology of other subset gliomas. My efforts on integrative data analysis of this highly curated data set usingoptimizedstatistical models will reflect the pending update to WHO classification system oftumorsin the central nervous system (CNS).
3) Comprehensive characterization of somatic fusion transcripts in Pan-Cancers. I have identified a panel of novel fusion transcripts across all of TCGA cancer types through transcriptomic profiling. Then I have predicted fusion proteins with kinase activity and hub function of pathway network based on the annotation of genetically mobile domains and functional domain architectures. I have evaluated a panel of in -frame gene fusions as potential driver mutations based on network fusion centrality hypothesis. I have also characterised the emerging complexity of genetic architecture in fusion transcripts through integrating genomic structure and somatic variants and delineating the distinct genomic patterns of fusion events across different cancer types. Overall my exploration of the pathogenetic impact and clinical relevance of candidate gene fusions have provided fundamental insights into the management of a subset of cancer patients by predicting the oncogenic signalling and specific drug targets encoded by these fusion genes.
Taken together, the translational genomic research I have conducted during my Ph.D. study will shed new light on precision medicine and contribute to the cancer research community. The novel classification concept, gene signature and fusion transcripts I have identified will address several hotly debated issues in translational genomics, such as complex interactions between tumor bulks and their adjacent microenvironments, prognostic markers for clinical diagnostics and personalized therapy, distinct patterns of genomic structure alterations and oncogenic events in different cancer types, therefore facilitating our understanding of genomic alterations and moving us towards the development of precision medicine
IceBreaker: Solving Cold Start Problem for Video Recommendation Engines
Internet has brought about a tremendous increase in content of all forms and,
in that, video content constitutes the major backbone of the total content
being published as well as watched. Thus it becomes imperative for video
recommendation engines such as Hulu to look for novel and innovative ways to
recommend the newly added videos to their users. However, the problem with new
videos is that they lack any sort of metadata and user interaction so as to be
able to rate the videos for the consumers. To this effect, this paper
introduces the several techniques we develop for the Content Based Video
Relevance Prediction (CBVRP) Challenge being hosted by Hulu for the ACM
Multimedia Conference 2018. We employ different architectures on the CBVRP
dataset to make use of the provided frame and video level features and generate
predictions of videos that are similar to the other videos. We also implement
several ensemble strategies to explore complementarity between both the types
of provided features. The obtained results are encouraging and will impel the
boundaries of research for multimedia based video recommendation systems
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