12 research outputs found

    Supporting Documentation for the 2008 Update to the Insulation Fact Sheet

    Full text link

    Evaluation of New Test Methods for Fire Fighting Clothing

    Get PDF
    Despite advancements in the development of synthetic fibers and materials that provide better insulation, fire ground burn injuries remain a significant issue. The current test methods for fire fighting clothing were investigated to determine their adequacy in evaluating the actual performance of clothing materials. This investigation uncovered several potential problems with the current test methods. A series of new, small scale, tests were used to evaluate the shortcomings of the current test methods and develop possible improvements. A small test apparatus, designed and donated by Ktech Corporation, was used to measure the thermal properties (thermal conductivity and volumetric heat capacity) of a series of fire fighting clothing materials. The thermal properties were estimated for single fabric layers, as well as ensembles, with various levels of moisture added to simulate actual end use conditions. In addition, a skin simulant sensor was used to assess the time to 2nd degree burn for exposures similar to those required in current standards for fire fighting clothing. A one dimensional heat conduction model was developed to predict the time to 2nd degree burn for the skin simulant sensor protected with outer shell materials that may be used as wildland fire fighting clothing, using the thermal property data obtained from earlier tests. An alternative method was developed to calculate the time to 2nd degree burn for ensembles evaluated with the new skin simulant sensor. The predictions for the time to 2nd degree burn obtained from the new skin simulant sensor were compared against results obtained using the sensor specified in the current test methods. The predictions for the skin simulant sensor were consistently shorter than those from the current test sensor. The current test sensor predictions for the time to 2nd degree burn were nominally 40% to 50% higher than the predictions from the skin simulant sensor during the evaluations of outer shell materials

    An In-Shoe Laser Doppler Sensor for Assessing Plantar Blood Flow in the Diabetic Foot

    Get PDF
    An in-shoe laser Doppler sensor for assessing plantar blood flow in the diabetic foot. Jonathan Edwin Cobb Plantar ulceration is a complication of the diabetic foot prevalent in adults with type 11 diabetes mellitus. Although neuropathy, microvascular disease and biornechanical factors are all implicated, the mechanism by which the tissue becomes pre-disposed to damage remains unclear. Recent theories suggest that the nutritional supply to the tissue is compromised, either by increased flow through the arteriovenous anastomoses ('capillary steal' theory) or through changes in the micro vascu I ature (haemodynamic hypothesis). Clinical data to support these ideas has been limited to assessment of the unclad foot under rest conditions. A limitation of previous studies has been the exclusion of static and dynamic tissue loading, despite extensive evidence that these biornechanical factors are essential in the development of plantar ulceration. The present study has overcome these problems by allowing assessment of plantar blood flow, in-shoe, during standing and walking. The system comprises a laser Doppler blood flux sensor operating at 780nm, load sensor, measurement shoe, instrumentation, and analysis software. In-vitro calibration was performed using standard techniques. An in-vivo study of a small group of diabetic subjects indicated differences in the blood flux response between diabetic neuropaths, diabetics with vascular complications and a control group. For example, following a loading period of 120s, relative increases in response from rest to peak were: Control (150% to 259%), Vascular (-70% to 242%), Neuropathic (109%-174%) and recovery times to 50% of the peak response were: Control (33s to 45s), Vascular (43s to >120s), Neuropathic (>120s). Dynamic re-perfusion rates (arbitrary units per millisecond) obtained for the swing phase of gait were: Control (6.1 a. u/ms to 7.9 a. u/ms), Vascular (4 a. u/ms to 6.2 a. u/ms), Neuropathic (2.3 a. u/ms to 4.5 a. u/ms)

    Marine Drug Research in China: Selected Papers from the 15-NASMD Conference

    Get PDF
    The Book covers this whole field, from the discovery of structurally new and bioactive natural products (including biomacromolecules), from marine macro-/micro-organisms, to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, both in vitro and in vivo, along with the synthesis and/or structural optimization of marine-derived lead compounds and their structure–activity relationships. Taken together, this Special Issue reprint not only provides inspiration for the discovery of marine-derived novel bioactive compounds, but also sheds light on the further research and development of marine candidate drugs

    Bryn Mawr Alumnae Bulletin, 1940

    Get PDF
    https://repository.brynmawr.edu/bmc_alumnae/1030/thumbnail.jp

    Bryn Mawr Alumnae Bulletin, 1940

    Get PDF
    https://repository.brynmawr.edu/bmc_alumnae/1030/thumbnail.jp
    corecore