Learning to recommend descriptive tags for questions in social forums

10.1145/2559157ACM Transactions on Information Systems321-ATIS

New advances in metabolic syndrome, from prevention to treatment. The role of diet and food

The definition of metabolic syndrome (MetS) has undergone several changes over the years due to the difficulty in establishing universal criteria for it. Underlying the disorders related to MetS is almost invariably a pro-inflammatory state related to altered glucose metabolism, which could lead to elevated cardiovascular risk. Indeed, the complications closely related to MetS are cardiovascular diseases (CVDs) and type 2 diabetes (T2D). It has been observed that the predisposition to metabolic syndrome is modulated by complex interactions between human microbiota, genetic factors, and diet. This review provides a summary of the last decade of literature related to three principal aspects of MetS: (i) the syndrome’s definition and classification, pathophysiology, and treatment approaches; (ii) prediction and diagnosis underlying the biomarkers identified by means of advanced methodologies (NMR, LC/GC-MS, and LC, LC-MS); and (iii) the role of foods and food components in prevention and/or treatment of MetS, demonstrating a possible role of specific foods intake in the development of MetS

Advancing Multi-Modal Deep Learning: Towards Language-Grounded Visual Understanding

Using deep learning, computer vision now rivals people at object recognition and detection, opening doors to tackle new challenges in image understanding. Among these challenges, understanding and reasoning about language grounded visual content is of fundamental importance to advancing artificial intelligence. Recently, multiple datasets and algorithms have been created as proxy tasks towards this goal, with visual question answering (VQA) being the most widely studied. In VQA, an algorithm needs to produce an answer to a natural language question about an image. However, our survey of datasets and algorithms for VQA uncovered several sources of dataset bias and sub-optimal evaluation metrics that allowed algorithms to perform well by merely exploiting superficial statistical patterns. In this dissertation, we describe new algorithms and datasets that address these issues. We developed two new datasets and evaluation metrics that enable a more accurate measurement of abilities of a VQA model, and also expand VQA to include new abilities, such as reading text, handling out-of-vocabulary words, and understanding data-visualization. We also created new algorithms for VQA that have helped advance the state-of-the-art for VQA, including an algorithm that surpasses humans on two different chart question answering datasets about bar-charts, line-graphs and pie charts. Finally, we provide a holistic overview of several yet-unsolved challenges in not only VQA but vision and language research at large. Despite enormous progress, we find that a robust understanding and integration of vision and language is still an elusive goal, and much of the progress may be misleading due to dataset bias, superficial correlations and flaws in standard evaluation metrics. We carefully study and categorize these issues for several vision and language tasks and outline several possible paths towards development of safe, robust and trustworthy AI for language-grounded visual understanding

Development of Authenticity Methods for Apple and Pear Juices

Due to its widespread global consumption and economic value, fruit juice is a common target for adulteration through debasing by unscrupulous producers. Two common methods of fruit juice adulteration are debasing with commercial sweeteners and juice-to-juice adulteration. The overarching goal of this research was to develop methods to detect the undeclared addition of less expensive commercial sweeteners to pear juice and the undeclared addition of apple to pear and pear to apple juice. Methods to detect the undeclared addition of high fructose corn syrup (HFCS), hydrolyzed inulin syrup (HIS) and total invert sugar (TIS) to commercial pear juice were developed through oligosaccharide profiling employing high performance anion exchange chromatography with pulsed amperometric detection (HPAE-PAD) and capillary gas chromatography with flame ionization detection (CGC-FID). Based on the application of these methods to intentional pear juice debasing, these three commercial sweeteners could be detected at levels of 0.5-3.0% (v/v). Coupled with the developed authenticity analysis for pear juice, the developed profiling methods were used to examine the carbohydrate/oligosaccharide profile of pear juice as a function of commercial processing. Chromatographic results showed that the majority of carbohydrate/oligosaccharide formation occurred during the mashing stage of juice production where enzymes (i.e. pectinases, hemicellulases and amylases) are employed. The remaining processing stages were found to have a minimal impact on the carbohydrate/oligosaccharide profile of commercial pear juice. Methods for the detection of juice-to-juice debasing between apple and pear juices were developed using phenolic profiling. High performance liquid chromatography with photodiode array detection (HPLC-PDA) was used to determine the phenolic profiles of commercial apple and pear juice concentrates from major world production regions. The phenolic profiles were used to identify fingerprint compounds for use in juice-to-juice adulteration detection. One phenolic marker was identified in apple juice and two in pear juice (excluding arbutin). These compounds were analyzed by UV-vis and NMR spectroscopic methods, and high resolution MS and LC-MS/MS spectrometry. Results from these analyses identified the fingerprint compounds as 4-O-p-coumarylquinic acid in commercial apple juice, and isorhamnetin-3-O¬-rutinoside and abscisic acid in commercial pear juice. The total phenolic content and antioxidant activities of the 27 apple and 32 pear juices used throughout this research were determined by the Folin-Ciocalteu (total phenolic content), HPLC-PDA (total phenolic chromatographic index), Trolox equivalent antioxidant activity (TEAC) and DPPH methods. The total phenolic content of apple and pear juices were found to be 294.7 ± 128.2 and 246.4 ± 45.1 ppm GAE and the total phenolic chromatographic indices were 128.8 ± 44.9 and 211.7 ± 57.2 ppm, respectively. The TEAC of apple and pear juices were found to be 130.8 ± 60.8 and 150.8 ± 63.9 mM Trolox/100 mL, while the DPPH radical scavenging abilities were 21.5 ± 12.1 and 13.6 ± 5.5 mL of DPPH/mL of juice, respectively

Development of a Corpus for User­based Scientific Question Answering

Tese de mestrado, Bioinformática e Biologia Computacional, Universidade de Lisboa, Faculdade de Ciências, 2021In recent years Question & Answering (QA) tasks became particularly relevant in the research field of natural language understanding. However, the lack of good quality datasets has been an important limiting factor in the quest for better models. Particularly in the biomedical domain, the scarcity of gold standard labelled datasets has been a recognized obstacle given its idiosyncrasies and complexities often require the participation of skilled domain¬specific experts in producing such datasets. To address this issue, a method for automatically gather Question¬Answer pairs from online QA biomedical forums has been suggested yielding a corpus named BiQA. The authors describe several strategies to validate this new dataset but a human manual verification has not been conducted. With this in mind, this dissertation was set out with the objectives of performing a manual verification of a sample of 1200 questions of BiQA and also to expanding these questions, by adding features, into a new corpus of text ¬ BiQA2 ¬ with the goal of contributing with a new corpusfor biomedical QA research. Regarding the manual verification of BiQA, a methodology for its characterization was laid out and allowed the identification of an array of potential problems related to the nature of its questions and answers aptness for which possible improvement solutions were presented. Concomitantly, the proposed new BiQA2 corpus ¬ created upon the validated questions and answers from the perused samples from BiQA ¬ builds new features similar to those observed in other biomedical corpus such as the BioASQ dataset. Both BiQA and BiQA2 were applied to deep learning strategies previously submitted to the BioASQ competition to assess their performance as a source of training data. Although the results achieved with the models created using BiQA2 exhibit limited capability pertaining to the BioASQ challenge, they also show some potential to contribute positively to model training in tasks such as Document re-ranking and answering to ‘yes/no’ questions

A Cross-domain and Cross-language Knowledge-based Representation of Text and its Meaning

Tesis por compendioNatural Language Processing (NLP) is a field of computer science, artificial intelligence, and computational linguistics concerned with the interactions between computers and human languages. One of its most challenging aspects involves enabling computers to derive meaning from human natural language. To do so, several meaning or context representations have been proposed with competitive performance. However, these representations still have room for improvement when working in a cross-domain or cross-language scenario. In this thesis we study the use of knowledge graphs as a cross-domain and cross-language representation of text and its meaning. A knowledge graph is a graph that expands and relates the original concepts belonging to a set of words. We obtain its characteristics using a wide-coverage multilingual semantic network as knowledge base. This allows to have a language coverage of hundreds of languages and millions human-general and -specific concepts. As starting point of our research we employ knowledge graph-based features - along with other traditional ones and meta-learning - for the NLP task of single- and cross-domain polarity classification. The analysis and conclusions of that work provide evidence that knowledge graphs capture meaning in a domain-independent way. The next part of our research takes advantage of the multilingual semantic network and focuses on cross-language Information Retrieval (IR) tasks. First, we propose a fully knowledge graph-based model of similarity analysis for cross-language plagiarism detection. Next, we improve that model to cover out-of-vocabulary words and verbal tenses and apply it to cross-language document retrieval, categorisation, and plagiarism detection. Finally, we study the use of knowledge graphs for the NLP tasks of community questions answering, native language identification, and language variety identification. The contributions of this thesis manifest the potential of knowledge graphs as a cross-domain and cross-language representation of text and its meaning for NLP and IR tasks. These contributions have been published in several international conferences and journals.El Procesamiento del Lenguaje Natural (PLN) es un campo de la informática, la inteligencia artificial y la lingüística computacional centrado en las interacciones entre las máquinas y el lenguaje de los humanos. Uno de sus mayores desafíos implica capacitar a las máquinas para inferir el significado del lenguaje natural humano. Con este propósito, diversas representaciones del significado y el contexto han sido propuestas obteniendo un rendimiento competitivo. Sin embargo, estas representaciones todavía tienen un margen de mejora en escenarios transdominios y translingües. En esta tesis estudiamos el uso de grafos de conocimiento como una representación transdominio y translingüe del texto y su significado. Un grafo de conocimiento es un grafo que expande y relaciona los conceptos originales pertenecientes a un conjunto de palabras. Sus propiedades se consiguen gracias al uso como base de conocimiento de una red semántica multilingüe de amplia cobertura. Esto permite tener una cobertura de cientos de lenguajes y millones de conceptos generales y específicos del ser humano. Como punto de partida de nuestra investigación empleamos características basadas en grafos de conocimiento - junto con otras tradicionales y meta-aprendizaje - para la tarea de PLN de clasificación de la polaridad mono- y transdominio. El análisis y conclusiones de ese trabajo muestra evidencias de que los grafos de conocimiento capturan el significado de una forma independiente del dominio. La siguiente parte de nuestra investigación aprovecha la capacidad de la red semántica multilingüe y se centra en tareas de Recuperación de Información (RI). Primero proponemos un modelo de análisis de similitud completamente basado en grafos de conocimiento para detección de plagio translingüe. A continuación, mejoramos ese modelo para cubrir palabras fuera de vocabulario y tiempos verbales, y lo aplicamos a las tareas translingües de recuperación de documentos, clasificación, y detección de plagio. Por último, estudiamos el uso de grafos de conocimiento para las tareas de PLN de respuesta de preguntas en comunidades, identificación del lenguaje nativo, y identificación de la variedad del lenguaje. Las contribuciones de esta tesis ponen de manifiesto el potencial de los grafos de conocimiento como representación transdominio y translingüe del texto y su significado en tareas de PLN y RI. Estas contribuciones han sido publicadas en diversas revistas y conferencias internacionales.El Processament del Llenguatge Natural (PLN) és un camp de la informàtica, la intel·ligència artificial i la lingüística computacional centrat en les interaccions entre les màquines i el llenguatge dels humans. Un dels seus majors reptes implica capacitar les màquines per inferir el significat del llenguatge natural humà. Amb aquest propòsit, diverses representacions del significat i el context han estat proposades obtenint un rendiment competitiu. No obstant això, aquestes representacions encara tenen un marge de millora en escenaris trans-dominis i trans-llenguatges. En aquesta tesi estudiem l'ús de grafs de coneixement com una representació trans-domini i trans-llenguatge del text i el seu significat. Un graf de coneixement és un graf que expandeix i relaciona els conceptes originals pertanyents a un conjunt de paraules. Les seves propietats s'aconsegueixen gràcies a l'ús com a base de coneixement d'una xarxa semàntica multilingüe d'àmplia cobertura. Això permet tenir una cobertura de centenars de llenguatges i milions de conceptes generals i específics de l'ésser humà. Com a punt de partida de la nostra investigació emprem característiques basades en grafs de coneixement - juntament amb altres tradicionals i meta-aprenentatge - per a la tasca de PLN de classificació de la polaritat mono- i trans-domini. L'anàlisi i conclusions d'aquest treball mostra evidències que els grafs de coneixement capturen el significat d'una forma independent del domini. La següent part de la nostra investigació aprofita la capacitat\hyphenation{ca-pa-ci-tat} de la xarxa semàntica multilingüe i se centra en tasques de recuperació d'informació (RI). Primer proposem un model d'anàlisi de similitud completament basat en grafs de coneixement per a detecció de plagi trans-llenguatge. A continuació, vam millorar aquest model per cobrir paraules fora de vocabulari i temps verbals, i ho apliquem a les tasques trans-llenguatges de recuperació de documents, classificació, i detecció de plagi. Finalment, estudiem l'ús de grafs de coneixement per a les tasques de PLN de resposta de preguntes en comunitats, identificació del llenguatge natiu, i identificació de la varietat del llenguatge. Les contribucions d'aquesta tesi posen de manifest el potencial dels grafs de coneixement com a representació trans-domini i trans-llenguatge del text i el seu significat en tasques de PLN i RI. Aquestes contribucions han estat publicades en diverses revistes i conferències internacionals.Franco Salvador, M. (2017). A Cross-domain and Cross-language Knowledge-based Representation of Text and its Meaning [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/84285TESISCompendi

COMPLEX QUESTION ANSWERING BASED ON A SEMANTIC DOMAIN MODEL OF CLINICAL MEDICINE

Much research in recent years has focused on question answering. Due to significant advances in answering simple fact-seeking questions, research is moving towards resolving complex questions. An approach adopted by many researchers is to decompose a complex question into a series of fact-seeking questions and reuse techniques developed for answering simple questions. This thesis presents an alternative novel approach to domain-specific complex question answering based on consistently applying a semantic domain model to question and document understanding as well as to answer extraction and generation. This study uses a semantic domain model of clinical medicine to encode (a) a clinician's information need expressed as a question on the one hand and (b) the meaning of scientific publications on the other to yield a common representation. It is hypothesized that this approach will work well for (1) finding documents that contain answers to clinical questions and (2) extracting these answers from the documents. The domain of clinical question answering was selected primarily because of its unparalleled resources that permit providing a proof by construction for this hypothesis. In addition, a working prototype of a clinical question answering system will support research in informed clinical decision making. The proposed methodology is based on the semantic domain model developed within the paradigm of Evidence Based Medicine. Three basic components of this model - the clinical task, a framework for capturing a synopsis of a clinical scenario that generated the question, and strength of evidence presented in an answer - are identified and discussed in detail. Algorithms and methods were developed that combine knowledge-based and statistical techniques to extract the basic components of the domain model from abstracts of biomedical articles. These algorithms serve as a foundation for the prototype end-to-end clinical question answering system that was built and evaluated to test the hypotheses. Evaluation of the system on test collections developed in the course of this work and based on real life clinical questions demonstrates feasibility of complex question answering and high accuracy information retrieval using a semantic domain model