Proactive Data Download and User Demand Shaping for Data Networks

In this work, we propose and study optimal proactive resource allocation and demand shaping for data networks. Motivated by the recent findings on the predictability of human behavior patterns in data networks, and the emergence of highly capable handheld devices, our design aims to smooth out the network traffic over time and minimize the data delivery costs. Our framework utilizes proactive data services as well as smart content recommendation schemes for shaping the demand. Proactive data services take place during the off-peak hours based on a statistical prediction of a demand profile for each user, whereas smart content recommendation assigns modified valuations to data items so as to render the users' demand less uncertain. Hence, our recommendation scheme aims to boost the performance of proactive services within the allowed flexibility of user requirements. We conduct theoretical performance analysis that quantifies the leveraged cost reduction through the proposed framework. We show that the cost reduction scales at the same rate as the cost function scales with the number of users. Further, we prove that \emph{demand shaping} through smart recommendation strictly reduces the incurred cost even below that of proactive downloads without recommendation

Does screening for diabetes in at-risk patients improve long-term outcomes?

No randomized clinical trials or prospective studies have demonstrated adequate evidence to screen individuals for diabetes mellitus. A recently published meta-analysis for the United States Preventative Services Task Force (USPSTF) stated that "until we have better evidence about its benefits, harms, and costs, the role of screening as a strategy to reduce the burden of suffering of diabetes will remain uncertain"� (strength of recommendation [SOR]: B, based on inconclusive studies). The group of patients most likely to benefit from diabetes screening are patients with hypertension (SOR: B), or those whose risk for coronary heart disease is such that a diagnosis of diabetes would mandate addition of aspirin or lipid-lowering agents (SOR: C)

A Fuzzy Tree Matching-Based Personalized E-Learning Recommender System

© 1993-2012 IEEE. The rapid development of e-learning systems provides learners with great opportunities to access learning activities online, and this greatly supports and enhances the learning practices. However, an issue reduces the success of application of e-learning systems; too many learning activities (such as various leaning materials, subjects, and learning resources) are emerging in an e-learning system, making it difficult for individual learners to select proper activities for their particular situations/requirements because there is no personalized service function. Recommender systems, which aim to provide personalized recommendations for products or services, can be used to solve this issue. However, e-learning systems need to be able to handle certain special requirements: 1) leaning activities and learners' profiles often present tree structures; 2) learning activities contain vague and uncertain data, such as the uncertain categories that the learning activities belong to; 3) there are pedagogical issues, such as the precedence relations between learning activities. To deal with the three requirements, this study first proposes a fuzzy tree-structured learning activity model, and a learner profile model to comprehensively describe the complex learning activities and learner profiles. In the two models, fuzzy category trees and related similarity measures are presented to infer the semantic relations between learning activities or learner requirements. Since it is impossible to have two completely same trees, in practice, a fuzzy tree matching method is carefully discussed. A fuzzy tree matching-based hybrid learning activity recommendation approach is then developed. This approach takes advantage of both the knowledge-based and collaborative filtering-based recommendation approaches, and considers both the semantic and collaborative filtering similarities between learners. Finally, an e-learning recommender system prototype is well designed and developed based on the proposed models and recommendation approach. Experiments are done to evaluate the proposed recommendation approach, and the experimental results demonstrate the good accuracy performance of the proposed approach. A comprehensive case study about learning activity recommendation further demonstrates the effectiveness of the fuzzy tree matching-based personalized e-learning recommender system in practice

The influence of national culture on the attitude towards mobile recommender systems

This is the post-print version of the final paper published in Technological Forecasting and Social Change. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.This study aimed to identify factors that influence user attitudes towards mobile recommender systems and to examine how these factors interact with cultural values to affect attitudes towards this technology. Based on the theory of reasoned action, belief factors for mobile recommender systems are identified in three dimensions: functional, contextual, and social. Hypotheses explaining different impacts of cultural values on the factors affecting attitudes were also proposed. The research model was tested based on data collected in China, South Korea, and the United Kingdom. Findings indicate that functional and social factors have significant impacts on user attitudes towards mobile recommender systems. The relationships between belief factors and attitudes are moderated by two cultural values: collectivism and uncertainty avoidance. The theoretical and practical implications of applying theory of reasoned action and innovation diffusion theory to explain the adoption of new technologies in societies with different cultures are also discussed.National Research Foundation of Korea Grant funded by the Korean governmen

Towards the implementation of a preference-and uncertain-aware solver using answer set programming

Logic programs with possibilistic ordered disjunction (or LPPODs) are a recently defined logic-programming framework based on logic programs with ordered disjunction and possibilistic logic. The framework inherits the properties of such formalisms and merging them, it supports a reasoning which is nonmonotonic, preference-and uncertain-aware. The LPPODs syntax allows to specify 1) preferences in a qualitative way, and 2) necessity values about the certainty of program clauses. As a result at semantic level, preferences and necessity values can be used to specify an order among program solutions. This class of program therefore fits well in the representation of decision problems where a best option has to be chosen taking into account both preferences and necessity measures about information. In this paper we study the computation and the complexity of the LPPODs semantics and we describe the algorithm for its implementation following on Answer Set Programming approach. We describe some decision scenarios where the solver can be used to choose the best solutions by checking whether an outcome is possibilistically preferred over another considering preferences and uncertainty at the same time.Postprint (published version

A prospective adaptive utility trial to validate performance of a novel urine exosome gene expression assay to predict high-grade prostate cancer in patients with prostate-specific antigen 2-10ng/ml at initial biopsy

BACKGROUND: Discriminating indolent from clinically significant prostate cancer (PCa) in the initial biopsy setting remains an important issue. Prospectively evaluated diagnostic assays are necessary to ensure efficacy and clinical adoption. OBJECTIVE: Performance and utility assessment of ExoDx Prostate (IntelliScore) (EPI) urine exosome gene expression assay versus standard clinical parameters for discriminating Grade Group (GG) ≥2 PCa from GG1 PCa and benign disease on initial biopsy. DESIGN, SETTING, AND PARTICIPANTS: A two-phase adaptive clinical utility study (NCT03031418) comparing EPI results with biopsy outcomes in men, with age ≥50 yr and prostate-specific antigen (PSA) 2-10ng/ml, scheduled for initial prostate biopsy. After EPI performance assessment during phase I, a clinical implementation document (ie, CarePath) was developed for utilizing the EPI test in phase II, where the biopsy decision is uncertain. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Performance evaluation of the EPI test in patients enrolled in phase I and publication of a consensus CarePath for phase II. RESULTS AND LIMITATIONS: In a total of 503 patients, with median age of 64 yr, median PSA 5.4ng/ml, 14% African American, 70% Caucasian, 53% positive biopsy rate (22% GG1, 17% GG2, and 15% ≥ GG3), EPI was superior to an optimized model of standard clinical parameters with an area under the curve (AUC) 0.70 versus 0.62, respectively, comparable with previously published results (n=519 patients, EPI AUC 0.71). Validated cut-point 15.6 would avoid 26% of unnecessary prostate biopsies and 20% of total biopsies, with negative predictive value (NPV) 89% and missing 7% of ≥GG2 PCa. Alternative cut-point 20 would avoid 40% of unnecessary biopsies and 31% of total biopsies, with NPV 89% and missing 11% of ≥GG2 PCa. The clinical investigators reached consensus recommending use of the 15.6 cut-point for phase II. Outcome of the decision impact cohort in phase II will be reported separately. CONCLUSIONS: EPI is a noninvasive, easy-to-use, gene expression urine assay, which has now been successfully validated in over 1000 patients across two prospective validation trials to stratify risk of ≥GG2 from GG1 cancer and benign disease. The test improves identification of patients with higher grade disease and would reduce the total number of unnecessary biopsies. PATIENT SUMMARY: It is challenging to predict which men are likely to have high-grade prostate cancer (PCa) at initial biopsy with prostate-specific antigen 2-10ng/ml. This study further demonstrates that the ExoDx Prostate (IntelliScore) test can predict ≥GG2 PCa at initial biopsy and defer unnecessary biopsies better than existing risk calculator\u27s and standard clinical data