Convolutional Neural Network for Stereotypical Motor Movement Detection in Autism

Autism Spectrum Disorders (ASDs) are often associated with specific atypical postural or motor behaviors, of which Stereotypical Motor Movements (SMMs) have a specific visibility. While the identification and the quantification of SMM patterns remain complex, its automation would provide support to accurate tuning of the intervention in the therapy of autism. Therefore, it is essential to develop automatic SMM detection systems in a real world setting, taking care of strong inter-subject and intra-subject variability. Wireless accelerometer sensing technology can provide a valid infrastructure for real-time SMM detection, however such variability remains a problem also for machine learning methods, in particular whenever handcrafted features extracted from accelerometer signal are considered. Here, we propose to employ the deep learning paradigm in order to learn discriminating features from multi-sensor accelerometer signals. Our results provide preliminary evidence that feature learning and transfer learning embedded in the deep architecture achieve higher accurate SMM detectors in longitudinal scenarios.Comment: Presented at 5th NIPS Workshop on Machine Learning and Interpretation in Neuroimaging (MLINI), 2015, (http://arxiv.org/html/1605.04435), Report-no: MLINI/2015/1

GART: The Gesture and Activity Recognition Toolkit

Presented at the 12th International Conference on Human-Computer Interaction, Beijing, China, July 2007.The original publication is available at www.springerlink.comThe Gesture and Activity Recognition Toolit (GART) is a user interface toolkit designed to enable the development of gesture-based applications. GART provides an abstraction to machine learning algorithms suitable for modeling and recognizing different types of gestures. The toolkit also provides support for the data collection and the training process. In this paper, we present GART and its machine learning abstractions. Furthermore, we detail the components of the toolkit and present two example gesture recognition applications

Upset or Collapse Detection System for ASD Children Using Smart Watch with Machine Learning Algorithm

ASD is characterised by severe and violent behavioural issues that are referred to as "meltdowns (upset) or tantrums (collapse)" and can include aggression, hyperactivity, intolerance, unpredictability and self-injury. This research work intends to develop and implement a non-invasive real-time Upset or Collapse Detection System (UCDS) for people with ASD. With a certain model of smart watch, the non-invasive biological indications such as Pulse Rate (PR), Skin Temperature (ST), and Galvanic Skin Reaction (GSR) can be artificially captured.  In order to create the UCDS, deep learning algorithms like CNN, LSTM, and the hybrid of CNN-LSTM are given the physiological signals that are captured to a server. The deep learning algorithm could recognise aberrant upset or collapse states from real-time physiological signs after being trained.  Deep learning algorithms including CNN, LSTM, and CNN-LSTM are used to train and test the proposed UCDS system, and it is discovered that hybrid CNN-LSTM beat them all with an average training and testing accuracy of 96% and a low mean absolute error (MAE) of 0.10 for training and 0.04 for testing.  Furthermore, the suggested UCDS system is supported by 93% of the ASD caretakers

Kinematic Assessment of Stereotypy in Spontaneous Movements in Infants

Movement variation constitutes a crucial feature of infant motor development. Reduced variation of spontaneous infant movements, i.e. stereotyped movements, may indicate severe neurological deficit at an early stage. Hitherto evaluation of movement variation has been mainly restricted to subjective assessment based on observation. This article introduces a method for quantitative assessment yielding an objective definition of stereotyped movements which may be used for the prognosis of neurological deficits such as cerebral palsy (CP). Movements of 3-months-old infants were recorded with an electromagnetic tracking system facilitating the analysis of joint angles of the upper and lower limb. A stereotypy score based on dynamic time warping has been developed describing movements which are self-similar in multiple degrees of freedom. For clinical evaluation, this measure was calculated in a group of infants at risk for neurological disorders (n=54) and a control group of typically developing children (n=21) on the basis of spontaneous movements at the age of three months. The stereotypy score was related to outcome at the age of 24 months in terms of CP (n=10) or no-CP (n=53). Using the stereotypy score of upper limb movements CP cases could be identified with a sensitivity of 90% and a specificity of 96%. The corresponding score of the leg movements did not allow for valid discrimination of the groups. The presented stereotypy feature is a promising candidate for a marker that may be used as a simple and noninvasive quantitative measure in the prediction of CP. The method can be adopted for the assessment of infant movement variation in research and clinical applications

Machine Learning and Virtual Reality on Body Movements¿ Behaviors to Classify Children with Autism Spectrum Disorder

[EN] Autism spectrum disorder (ASD) is mostly diagnosed according to behavioral symptoms in sensory, social, and motor domains. Improper motor functioning, during diagnosis, involves the qualitative evaluation of stereotyped and repetitive behaviors, while quantitative methods that classify body movements' frequencies of children with ASD are less addressed. Recent advances in neuroscience, technology, and data analysis techniques are improving the quantitative and ecological validity methods to measure specific functioning in ASD children. On one side, cutting-edge technologies, such as cameras, sensors, and virtual reality can accurately detect and classify behavioral biomarkers, as body movements in real-life simulations. On the other, machine-learning techniques are showing the potential for identifying and classifying patients' subgroups. Starting from these premises, three real-simulated imitation tasks have been implemented in a virtual reality system whose aim is to investigate if machine-learning methods on movement features and frequency could be useful in discriminating ASD children from children with typical neurodevelopment. In this experiment, 24 children with ASD and 25 children with typical neurodevelopment participated in a multimodal virtual reality experience, and changes in their body movements were tracked by a depth sensor camera during the presentation of visual, auditive, and olfactive stimuli. The main results showed that ASD children presented larger body movements than TD children, and that head, trunk, and feet represent the maximum classification with an accuracy of 82.98%. Regarding stimuli, visual condition showed the highest accuracy (89.36%), followed by the visual-auditive stimuli (74.47%), and visual-auditive-olfactory stimuli (70.21%). Finally, the head showed the most consistent performance along with the stimuli, from 80.85% in visual to 89.36% in visual-auditive-olfactory condition. The findings showed the feasibility of applying machine learning and virtual reality to identify body movements' biomarkers that could contribute to improving ASD diagnosis.This work was supported by the Spanish Ministry of Economy, Industry, and Competitiveness funded project "Immersive virtual environment for the evaluation and training of children with autism spectrum disorder: T Room" (IDI-20170912) and by the Generalitat Valenciana funded project REBRAND (PROMETEO/2019/105). Furthermore, this work was co-founded by the European Union through the Operational Program of the European Regional development Fund (ERDF) of the Valencian Community 2014-2020 (IDIFEDER/2018/029).Alcañiz Raya, ML.; Marín-Morales, J.; Minissi, ME.; Teruel Garcia, G.; Abad, L.; Chicchi-Giglioli, IA. (2020). Machine Learning and Virtual Reality on Body Movements¿ Behaviors to Classify Children with Autism Spectrum Disorder. Journal of Clinical Medicine. 9(5):1-20. https://doi.org/10.3390/jcm9051260S12095https://www.who.int/news-room/fact-sheets/detail/autism-spectrum-disordersAnagnostou, E., Zwaigenbaum, L., Szatmari, P., Fombonne, E., Fernandez, B. A., Woodbury-Smith, M., … Scherer, S. W. (2014). Autism spectrum disorder: advances in evidence-based practice. Canadian Medical Association Journal, 186(7), 509-519. doi:10.1503/cmaj.121756Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., & Pickles, A. (2006). Autism From 2 to 9 Years of Age. Archives of General Psychiatry, 63(6), 694. doi:10.1001/archpsyc.63.6.694Schmidt, L., Kirchner, J., Strunz, S., Broźus, J., Ritter, K., Roepke, S., & Dziobek, I. (2015). Psychosocial Functioning and Life Satisfaction in Adults With Autism Spectrum Disorder Without Intellectual Impairment. Journal of Clinical Psychology, 71(12), 1259-1268. doi:10.1002/jclp.22225Turner, M. (1999). Annotation: Repetitive Behaviour in Autism: A Review of Psychological Research. Journal of Child Psychology and Psychiatry, 40(6), 839-849. doi:10.1111/1469-7610.00502Lewis, M. H., & Bodfish, J. W. (1998). Repetitive behavior disorders in autism. Mental Retardation and Developmental Disabilities Research Reviews, 4(2), 80-89. doi:10.1002/(sici)1098-2779(1998)4:23.0.co;2-0Mahone, E. M., Bridges, D., Prahme, C., & Singer, H. S. (2004). Repetitive arm and hand movements (complex motor stereotypies) in children. The Journal of Pediatrics, 145(3), 391-395. doi:10.1016/j.jpeds.2004.06.014MacDonald, R., Green, G., Mansfield, R., Geckeler, A., Gardenier, N., Anderson, J., … Sanchez, J. (2007). Stereotypy in young children with autism and typically developing children. Research in Developmental Disabilities, 28(3), 266-277. doi:10.1016/j.ridd.2006.01.004Singer, H. S. (2009). Motor Stereotypies. Seminars in Pediatric Neurology, 16(2), 77-81. doi:10.1016/j.spen.2009.03.008Lidstone, J., Uljarević, M., Sullivan, J., Rodgers, J., McConachie, H., Freeston, M., … Leekam, S. (2014). Relations among restricted and repetitive behaviors, anxiety and sensory features in children with autism spectrum disorders. Research in Autism Spectrum Disorders, 8(2), 82-92. doi:10.1016/j.rasd.2013.10.001GOLDMAN, S., WANG, C., SALGADO, M. W., GREENE, P. E., KIM, M., & RAPIN, I. (2009). Motor stereotypies in children with autism and other developmental disorders. Developmental Medicine & Child Neurology, 51(1), 30-38. doi:10.1111/j.1469-8749.2008.03178.xLord, C., Rutter, M., & Le Couteur, A. (1994). Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659-685. doi:10.1007/bf02172145Volkmar, F. R., State, M., & Klin, A. (2009). Autism and autism spectrum disorders: diagnostic issues for the coming decade. Journal of Child Psychology and Psychiatry, 50(1-2), 108-115. doi:10.1111/j.1469-7610.2008.02010.xReaven, J. A., Hepburn, S. L., & Ross, R. G. (2008). Use of the ADOS and ADI-R in Children with Psychosis: Importance of Clinical Judgment. Clinical Child Psychology and Psychiatry, 13(1), 81-94. doi:10.1177/1359104507086343Torres, E. B., Brincker, M., Isenhower, R. W., Yanovich, P., Stigler, K. A., Nurnberger, J. I., … José, J. V. (2013). Autism: the micro-movement perspective. Frontiers in Integrative Neuroscience, 7. doi:10.3389/fnint.2013.00032Möricke, E., Buitelaar, J. K., & Rommelse, N. N. J. (2015). Do We Need Multiple Informants When Assessing Autistic Traits? The Degree of Report Bias on Offspring, Self, and Spouse Ratings. Journal of Autism and Developmental Disorders, 46(1), 164-175. doi:10.1007/s10803-015-2562-yCHAYTOR, N., SCHMITTEREDGECOMBE, M., & BURR, R. (2006). Improving the ecological validity of executive functioning assessment. Archives of Clinical Neuropsychology, 21(3), 217-227. doi:10.1016/j.acn.2005.12.002Brunswik, E. (1955). Representative design and probabilistic theory in a functional psychology. Psychological Review, 62(3), 193-217. doi:10.1037/h0047470Gillberg, C., & Rasmussen, P. (1994). Brief report: Four case histories and a literature review of williams syndrome and autistic behavior. Journal of Autism and Developmental Disorders, 24(3), 381-393. doi:10.1007/bf02172235Parsons, S. (2016). Authenticity in Virtual Reality for assessment and intervention in autism: A conceptual review. Educational Research Review, 19, 138-157. doi:10.1016/j.edurev.2016.08.001Francis, K. (2005). Autism interventions: a critical update. Developmental Medicine & Child Neurology, 47(7), 493-499. doi:10.1017/s0012162205000952Albinali, F., Goodwin, M. S., & Intille, S. S. (2009). Recognizing stereotypical motor movements in the laboratory and classroom. Proceedings of the 11th international conference on Ubiquitous computing. doi:10.1145/1620545.1620555Pyles, D. A. M., Riordan, M. M., & Bailey, J. S. (1997). The stereotypy analysis: An instrument for examining environmental variables associated with differential rates of stereotypic behavior. Research in Developmental Disabilities, 18(1), 11-38. doi:10.1016/s0891-4222(96)00034-0Nosek, B. A., Hawkins, C. B., & Frazier, R. S. (2011). Implicit social cognition: from measures to mechanisms. Trends in Cognitive Sciences, 15(4), 152-159. doi:10.1016/j.tics.2011.01.005Forscher, P. S., Lai, C. K., Axt, J. R., Ebersole, C. R., Herman, M., Devine, P. G., & Nosek, B. A. (2019). A meta-analysis of procedures to change implicit measures. Journal of Personality and Social Psychology, 117(3), 522-559. doi:10.1037/pspa0000160LeDoux, J. E., & Pine, D. S. (2016). Using Neuroscience to Help Understand Fear and Anxiety: A Two-System Framework. American Journal of Psychiatry, 173(11), 1083-1093. doi:10.1176/appi.ajp.2016.16030353Fenning, R. M., Baker, J. K., Baucom, B. R., Erath, S. A., Howland, M. A., & Moffitt, J. (2017). Electrodermal Variability and Symptom Severity in Children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 47(4), 1062-1072. doi:10.1007/s10803-016-3021-0Nikula, R. (1991). Psychological Correlates of Nonspecific Skin Conductance Responses. Psychophysiology, 28(1), 86-90. doi:10.1111/j.1469-8986.1991.tb03392.xAlcañiz Raya, M., Chicchi Giglioli, I. A., Marín-Morales, J., Higuera-Trujillo, J. L., Olmos, E., Minissi, M. E., … Abad, L. (2020). Application of Supervised Machine Learning for Behavioral Biomarkers of Autism Spectrum Disorder Based on Electrodermal Activity and Virtual Reality. Frontiers in Human Neuroscience, 14. doi:10.3389/fnhum.2020.00090Cunningham, W. A., Raye, C. L., & Johnson, M. K. (2004). Implicit and Explicit Evaluation: fMRI Correlates of Valence, Emotional Intensity, and Control in the Processing of Attitudes. Journal of Cognitive Neuroscience, 16(10), 1717-1729. doi:10.1162/0898929042947919Kopton, I. M., & Kenning, P. (2014). Near-infrared spectroscopy (NIRS) as a new tool for neuroeconomic research. Frontiers in Human Neuroscience, 8. doi:10.3389/fnhum.2014.00549Nickel, P., & Nachreiner, F. (2003). Sensitivity and Diagnosticity of the 0.1-Hz Component of Heart Rate Variability as an Indicator of Mental Workload. Human Factors: The Journal of the Human Factors and Ergonomics Society, 45(4), 575-590. doi:10.1518/hfes.45.4.575.27094Di Martino, A., Yan, C.-G., Li, Q., Denio, E., Castellanos, F. X., Alaerts, K., … Milham, M. P. (2013). The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism. Molecular Psychiatry, 19(6), 659-667. doi:10.1038/mp.2013.78Van Hecke, A. V., Lebow, J., Bal, E., Lamb, D., Harden, E., Kramer, A., … Porges, S. W. (2009). Electroencephalogram and Heart Rate Regulation to Familiar and Unfamiliar People in Children With Autism Spectrum Disorders. Child Development, 80(4), 1118-1133. doi:10.1111/j.1467-8624.2009.01320.xCoronato, A., De Pietro, G., & Paragliola, G. (2014). A situation-aware system for the detection of motion disorders of patients with Autism Spectrum Disorders. Expert Systems with Applications, 41(17), 7868-7877. doi:10.1016/j.eswa.2014.05.011Goodwin, M. S., Intille, S. S., Albinali, F., & Velicer, W. F. (2010). Automated Detection of Stereotypical Motor Movements. Journal of Autism and Developmental Disorders, 41(6), 770-782. doi:10.1007/s10803-010-1102-zRodrigues, J. L., Gonçalves, N., Costa, S., & Soares, F. (2013). Stereotyped movement recognition in children with ASD. Sensors and Actuators A: Physical, 202, 162-169. doi:10.1016/j.sna.2013.04.019Crippa, A., Salvatore, C., Perego, P., Forti, S., Nobile, M., Molteni, M., & Castiglioni, I. (2015). Use of Machine Learning to Identify Children with Autism and Their Motor Abnormalities. Journal of Autism and Developmental Disorders, 45(7), 2146-2156. doi:10.1007/s10803-015-2379-8Wedyan, M., Al-Jumaily, A., & Crippa, A. (2019). Using machine learning to perform early diagnosis of Autism Spectrum Disorder based on simple upper limb movements. International Journal of Hybrid Intelligent Systems, 15(4), 195-206. doi:10.3233/his-190278Parsons, S., Mitchell, P., & Leonard, A. (2004). The Use and Understanding of Virtual Environments by Adolescents with Autistic Spectrum Disorders. Journal of Autism and Developmental Disorders, 34(4), 449-466. doi:10.1023/b:jadd.0000037421.98517.8dParsons, T. D., Rizzo, A. A., Rogers, S., & York, P. (2009). Virtual reality in paediatric rehabilitation: A review. Developmental Neurorehabilitation, 12(4), 224-238. doi:10.1080/17518420902991719Bowman, D. A., Gabbard, J. L., & Hix, D. (2002). A Survey of Usability Evaluation in Virtual Environments: Classification and Comparison of Methods. Presence: Teleoperators and Virtual Environments, 11(4), 404-424. doi:10.1162/105474602760204309Pastorelli, E., & Herrmann, H. (2013). A Small-scale, Low-budget Semi-immersive Virtual Environment for Scientific Visualization and Research. Procedia Computer Science, 25, 14-22. doi:10.1016/j.procs.2013.11.003Cobb, S. V. G., Nichols, S., Ramsey, A., & Wilson, J. R. (1999). Virtual Reality-Induced Symptoms and Effects (VRISE). Presence: Teleoperators and Virtual Environments, 8(2), 169-186. doi:10.1162/105474699566152Wallace, S., Parsons, S., Westbury, A., White, K., White, K., & Bailey, A. (2010). Sense of presence and atypical social judgments in immersive virtual environments. Autism, 14(3), 199-213. doi:10.1177/1362361310363283Lorenzo, G., Lledó, A., Arráez-Vera, G., & Lorenzo-Lledó, A. (2018). The application of immersive virtual reality for students with ASD: A review between 1990–2017. Education and Information Technologies, 24(1), 127-151. doi:10.1007/s10639-018-9766-7Bailenson, J. N., Yee, N., Merget, D., & Schroeder, R. (2006). The Effect of Behavioral Realism and Form Realism of Real-Time Avatar Faces on Verbal Disclosure, Nonverbal Disclosure, Emotion Recognition, and Copresence in Dyadic Interaction. Presence: Teleoperators and Virtual Environments, 15(4), 359-372. doi:10.1162/pres.15.4.359Cipresso, P., Giglioli, I. A. C., Raya, M. A., & Riva, G. (2018). The Past, Present, and Future of Virtual and Augmented Reality Research: A Network and Cluster Analysis of the Literature. Frontiers in Psychology, 9. doi:10.3389/fpsyg.2018.02086Cummings, J. J., & Bailenson, J. N. (2015). How Immersive Is Enough? A Meta-Analysis of the Effect of Immersive Technology on User Presence. Media Psychology, 19(2), 272-309. doi:10.1080/15213269.2015.1015740Skalski, P., & Tamborini, R. (2007). The Role of Social Presence in Interactive Agent-Based Persuasion. Media Psychology, 10(3), 385-413. doi:10.1080/15213260701533102Slater, M. (2009). Place illusion and plausibility can lead to realistic behaviour in immersive virtual environments. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1535), 3549-3557. doi:10.1098/rstb.2009.0138Baños, R. M., Botella, C., Garcia-Palacios, A., Villa, H., Perpiña, C., & Alcañiz, M. (2000). Presence and Reality Judgment in Virtual Environments: A Unitary Construct? CyberPsychology & Behavior, 3(3), 327-335. doi:10.1089/10949310050078760Bente, G., Rüggenberg, S., Krämer, N. C., & Eschenburg, F. (2008). Avatar-Mediated Networking: Increasing Social Presence and Interpersonal Trust in Net-Based Collaborations. Human Communication Research, 34(2), 287-318. doi:10.1111/j.1468-2958.2008.00322.xHeeter, C. (1992). Being There: The Subjective Experience of Presence. Presence: Teleoperators and Virtual Environments, 1(2), 262-271. doi:10.1162/pres.1992.1.2.262Sanchez-Vives, M. V., & Slater, M. (2005). From presence to consciousness through virtual reality. Nature Reviews Neuroscience, 6(4), 332-339. doi:10.1038/nrn1651Mohr, D. C., Burns, M. N., Schueller, S. M., Clarke, G., & Klinkman, M. (2013). Behavioral Intervention Technologies: Evidence review and recommendations for future research in mental health. General Hospital Psychiatry, 35(4), 332-338. doi:10.1016/j.genhosppsych.2013.03.008Neguț, A., Matu, S.-A., Sava, F. A., & David, D. (2016). Virtual reality measures in neuropsychological assessment: a meta-analytic review. The Clinical Neuropsychologist, 30(2), 165-184. doi:10.1080/13854046.2016.1144793Riva, G. (2005). Virtual Reality in Psychotherapy: Review. CyberPsychology & Behavior, 8(3), 220-230. doi:10.1089/cpb.2005.8.220Valmaggia, L. R., Latif, L., Kempton, M. J., & Rus-Calafell, M. (2016). Virtual reality in the psychological treatment for mental health problems: An systematic review of recent evidence. Psychiatry Research, 236, 189-195. doi:10.1016/j.psychres.2016.01.015Mesa-Gresa, P., Gil-Gómez, H., Lozano-Quilis, J.-A., & Gil-Gómez, J.-A. (2018). Effectiveness of Virtual Reality for Children and Adolescents with Autism Spectrum Disorder: An Evidence-Based Systematic Review. Sensors, 18(8), 2486. doi:10.3390/s18082486Cheng, Y., & Ye, J. (2010). Exploring the social competence of students with autism spectrum conditions in a collaborative virtual learning environment – The pilot study. Computers & Education, 54(4), 1068-1077. doi:10.1016/j.compedu.2009.10.011Jarrold, W., Mundy, P., Gwaltney, M., Bailenson, J., Hatt, N., McIntyre, N., … Swain, L. (2013). Social Attention in a Virtual Public Speaking Task in Higher Functioning Children With Autism. Autism Research, 6(5), 393-410. doi:10.1002/aur.1302Forgeot d’Arc, B., Ramus, F., Lefebvre, A., Brottier, D., Zalla, T., Moukawane, S., … Delorme, R. (2014). Atypical Social Judgment and Sensitivity to Perceptual Cues in Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 46(5), 1574-1581. doi:10.1007/s10803-014-2208-5Maskey, M., Lowry, J., Rodgers, J., McConachie, H., & Parr, J. R. (2014). Reducing Specific Phobia/Fear in Young People with Autism Spectrum Disorders (ASDs) through a Virtual Reality Environment Intervention. PLoS ONE, 9(7), e100374. doi:10.1371/journal.pone.0100374Baron-Cohen, S., Ashwin, E., Ashwin, C., Tavassoli, T., & Chakrabarti, B. (2009). Talent in autism: hyper-systemizing, hyper-attention to detail and sensory hypersensitivity. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1522), 1377-1383. doi:10.1098/rstb.2008.0337Tomchek, S. D., Huebner, R. A., & Dunn, W. (2014). Patterns of sensory processing in children with an autism spectrum disorder. Research in Autism Spectrum Disorders, 8(9), 1214-1224. doi:10.1016/j.rasd.2014.06.006Boyd, B. A., Baranek, G. T., Sideris, J., Poe, M. D., Watson, L. R., Patten, E., & Miller, H. (2010). Sensory features and repetitive behaviors in children with autism and developmental delays. Autism Research, n/a-n/a. doi:10.1002/aur.124Gabriels, R. L., Agnew, J. A., Miller, L. J., Gralla, J., Pan, Z., Goldson, E., … Hooks, E. (2008). Is there a relationship between restricted, repetitive, stereotyped behaviors and interests and abnormal sensory response in children with autism spectrum disorders? Research in Autism Spectrum Disorders, 2(4), 660-670. doi:10.1016/j.rasd.2008.02.002Cao, Z., Hidalgo, G., Simon, T., Wei, S.-E., & Sheikh, Y. (2021). OpenPose: Realtime Multi-Person 2D Pose Estimation Using Part Affinity Fields. IEEE Transactions on Pattern Analysis and Machine Intelligence, 43(1), 172-186. doi:10.1109/tpami.2019.2929257Schölkopf, B., Smola, A. J., Williamson, R. C., & Bartlett, P. L. (2000). New Support Vector Algorithms. Neural Computation, 12(5), 1207-1245. doi:10.1162/089976600300015565Yan, K., & Zhang, D. (2015). Feature selection and analysis on correlated gas sensor data with recursive feature elimination. Sensors and Actuators B: Chemical, 212, 353-363. doi:10.1016/j.snb.2015.02.025Chang, C.-C., & Lin, C.-J. (2011). LIBSVM. ACM Transactions on Intelligent Systems and Technology, 2(3), 1-27. doi:10.1145/1961189.1961199O’Neill, M., & Jones, R. S. P. (1997). Journal of Autism and Developmental Disorders, 27(3), 283-293. doi:10.1023/a:1025850431170Foss-Feig, J. H., Kwakye, L. D., Cascio, C. J., Burnette, C. P., Kadivar, H., Stone, W. L., & Wallace, M. T. (2010). An extended multisensory temporal binding window in autism spectrum disorders. Experimental Brain Research, 203(2), 381-389. doi:10.1007/s00221-010-2240-4Courchesne, E., Lincoln, A. J., Kilman, B. A., & Galambos, R. (1985). Event-related brain potential correlates of the processing of novel visual and auditory information in autism. Journal of Autism and Developmental Disorders, 15(1), 55-76. doi:10.1007/bf01837899Russo, N., Foxe, J. J., Brandwein, A. B., Altschuler, T., Gomes, H., & Molholm, S. (2010). Multisensory processing in children with autism: high-density electrical mapping of auditory-somatosensory integration. Autism Research, 3(5), 253-267. doi:10.1002/aur.152Ament, K., Mejia, A., Buhlman, R., Erklin, S., Caffo, B., Mostofsky, S., & Wodka, E. (2014). Evidence for Specificity of Motor Impairments in Catching and Balance in Children with Autism. Journal of Autism and Developmental Disorders, 45(3), 742-751. doi:10.1007/s10803-014-2229-

Wearable assistive technologies for autism : opportunities and challenges

Autism is a lifelong developmental condition that affects how people perceive the world and interact with others. Challenges with typical social engagement, common in the autism experience, can have a significant negative impact on the quality of life of individuals and families living with autism. Recent advances in sensing, intelligent, and interactive technologies can enable new forms of assistive and augmentative technologies to support social interactions. However, researchers have not yet demonstrated effectiveness of these technologies in long-term real-world use. This paper presents an overview of social and sensory challenges of autism, which offer great opportunities and challenges for the design and development of assistive technologies. We review the existing work on developing wearable technologies for autism particularly to assist social interactions, analyse their potential and limitations, and discuss future research directions.PostprintPeer reviewe

Child's play: activity recognition for monitoring children's developmental progress with augmented toys

The way in which infants play with objects can be indicative of their developmental progress and may serve as an early indicator for developmental delays. However, the observation of children interacting with toys for the purpose of quantitative analysis can be a difficult task. To better quantify how play may serve as an early indicator, researchers have conducted retrospective studies examining the differences in object play behaviors among infants. However, such studies require that researchers repeatedly inspect videos of play often at speeds much slower than real-time to indicate points of interest. The research presented in this dissertation examines whether a combination of sensors embedded within toys and automatic pattern recognition of object play behaviors can help expedite this process. For my dissertation, I developed the Child'sPlay system which uses augmented toys and statistical models to automatically provide quantitative measures of object play interactions, as well as, provide the PlayView interface to view annotated play data for later analysis. In this dissertation, I examine the hypothesis that sensors embedded in objects can provide sufficient data for automatic recognition of certain exploratory, relational, and functional object play behaviors in semi-naturalistic environments and that a continuum of recognition accuracy exists which allows automatic indexing to be useful for retrospective review. I designed several augmented toys and used them to collect object play data from more than fifty play sessions. I conducted pattern recognition experiments over this data to produce statistical models that automatically classify children's object play behaviors. In addition, I conducted a user study with twenty participants to determine if annotations automatically generated from these models help improve performance in retrospective review tasks. My results indicate that these statistical models increase user performance and decrease perceived effort when combined with the PlayView interface during retrospective review. The presence of high quality annotations are preferred by users and promotes an increase in the effective retrieval rates of object play behaviors.Ph.D.Committee Chair: Starner, Thad E.; Committee Co-Chair: Abowd, Gregory D.; Committee Member: Arriaga, Rosa; Committee Member: Jackson, Melody Moore; Committee Member: Lukowicz, Paul; Committee Member: Rehg, James M